In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research

This Special Issue published one editorial, eight articles and four reviews from approximately one hundred authors. It aimed to provide cutting-edge research on pre-clinical development and the clinical translation of radiopharmaceuticals within the molecular imaging community. The Special Issue cov...

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collection Directory of Open Access Books
description This Special Issue published one editorial, eight articles and four reviews from approximately one hundred authors. It aimed to provide cutting-edge research on pre-clinical development and the clinical translation of radiopharmaceuticals within the molecular imaging community. The Special Issue covered radioligand development, existing radiotracer optimization, imaging agent evaluation in animal models, the clinical production of radiopharmaceuticals, and investigative research on the use of molecular imaging probes in human subjects. We appreciate all the authors’ significant contributions to this Special Issue and hope the readers will enjoy the content.
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institution Directory of Open Access Books
language eng
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1007942024-03-28T03:33:17Z In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research Yue, Xuyi nanoparticle multimodal imaging photoacoustic heterobivalent peptide Alzheimer’s disease amyloid-beta animal model astrocyte blood–brain barrier imaging metabolism microglia neuroinflammation neurotransmitter receptors positron emission tomography synaptic density vascular imaging FDG PET/CT microvasculature imaging ABC-transporter drug-induced liver injury hepatotoxicity organic anion-transporting polypeptide pharmacokinetics liver function SLC-transporter V/Q PET/CT [68Ga]Ga-MAA 68Ga-labelled carbon nanoparticles glioblastoma fluorescence guided surgery 5-ALA fluorescein NIR-AZA magnetic resonance imaging high resolution hybrid imaging psychiatric disorders extracellular vesicles (EVs) umbilical cord mesenchymal stem cell (UCMSC) diabetes I-124 positron emission tomography (PET) intravenous (I.V.) administration intra-arterial (I.A.) administration biodistribution fluorine-18 PET oxime PSMA lipophilicity radiometals copper-61 liquid targets post-processing [61Cu]Cu-DOTA-NOC [61Cu]Cu-DOTA-TOC [61Cu]Cu-DOTA-TATE FAP 99mTc-FAP inhibitor 99mTc-labeled iFAP tumor microenvironment SPECT GluN1/2B receptors NMDA [3H]ifenprodil σ1 and σ2 receptors receptor occupancy PET imaging drug development neurodegenerative diseases n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This Special Issue published one editorial, eight articles and four reviews from approximately one hundred authors. It aimed to provide cutting-edge research on pre-clinical development and the clinical translation of radiopharmaceuticals within the molecular imaging community. The Special Issue covered radioligand development, existing radiotracer optimization, imaging agent evaluation in animal models, the clinical production of radiopharmaceuticals, and investigative research on the use of molecular imaging probes in human subjects. We appreciate all the authors’ significant contributions to this Special Issue and hope the readers will enjoy the content. 2023-06-23T09:42:20Z 2023-06-23T09:42:20Z 2023 book ONIX_20230623_9783036573915_26 9783036573915 9783036573908 https://directory.doabooks.org/handle/20.500.12854/100794 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7256 https://mdpi.com/books/pdfview/book/7256 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-7390-8 10.3390/books978-3-0365-7390-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036573915 9783036573908 220 Basel open access
spellingShingle nanoparticle
multimodal imaging
photoacoustic
heterobivalent peptide
Alzheimer’s disease
amyloid-beta
animal model
astrocyte
blood–brain barrier
imaging
metabolism
microglia
neuroinflammation
neurotransmitter receptors
positron emission tomography
synaptic density
vascular imaging
FDG
PET/CT
microvasculature imaging
ABC-transporter
drug-induced liver injury
hepatotoxicity
organic anion-transporting polypeptide
pharmacokinetics
liver function
SLC-transporter
V/Q PET/CT
[68Ga]Ga-MAA
68Ga-labelled carbon nanoparticles
glioblastoma
fluorescence guided surgery
5-ALA
fluorescein
NIR-AZA
magnetic resonance imaging
high resolution
hybrid imaging
psychiatric disorders
extracellular vesicles (EVs)
umbilical cord mesenchymal stem cell (UCMSC)
diabetes
I-124
positron emission tomography (PET)
intravenous (I.V.) administration
intra-arterial (I.A.) administration
biodistribution
fluorine-18
PET
oxime
PSMA
lipophilicity
radiometals
copper-61
liquid targets
post-processing
[61Cu]Cu-DOTA-NOC
[61Cu]Cu-DOTA-TOC
[61Cu]Cu-DOTA-TATE
FAP
99mTc-FAP inhibitor
99mTc-labeled iFAP
tumor microenvironment
SPECT
GluN1/2B receptors
NMDA
[3H]ifenprodil
σ1 and σ2 receptors
receptor occupancy
PET imaging
drug development
neurodegenerative diseases
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research
title In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research
title_full In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research
title_fullStr In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research
title_full_unstemmed In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research
title_short In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research
title_sort in vivo nuclear molecular imaging in drug development and pharmacological research
topic nanoparticle
multimodal imaging
photoacoustic
heterobivalent peptide
Alzheimer’s disease
amyloid-beta
animal model
astrocyte
blood–brain barrier
imaging
metabolism
microglia
neuroinflammation
neurotransmitter receptors
positron emission tomography
synaptic density
vascular imaging
FDG
PET/CT
microvasculature imaging
ABC-transporter
drug-induced liver injury
hepatotoxicity
organic anion-transporting polypeptide
pharmacokinetics
liver function
SLC-transporter
V/Q PET/CT
[68Ga]Ga-MAA
68Ga-labelled carbon nanoparticles
glioblastoma
fluorescence guided surgery
5-ALA
fluorescein
NIR-AZA
magnetic resonance imaging
high resolution
hybrid imaging
psychiatric disorders
extracellular vesicles (EVs)
umbilical cord mesenchymal stem cell (UCMSC)
diabetes
I-124
positron emission tomography (PET)
intravenous (I.V.) administration
intra-arterial (I.A.) administration
biodistribution
fluorine-18
PET
oxime
PSMA
lipophilicity
radiometals
copper-61
liquid targets
post-processing
[61Cu]Cu-DOTA-NOC
[61Cu]Cu-DOTA-TOC
[61Cu]Cu-DOTA-TATE
FAP
99mTc-FAP inhibitor
99mTc-labeled iFAP
tumor microenvironment
SPECT
GluN1/2B receptors
NMDA
[3H]ifenprodil
σ1 and σ2 receptors
receptor occupancy
PET imaging
drug development
neurodegenerative diseases
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet nanoparticle
multimodal imaging
photoacoustic
heterobivalent peptide
Alzheimer’s disease
amyloid-beta
animal model
astrocyte
blood–brain barrier
imaging
metabolism
microglia
neuroinflammation
neurotransmitter receptors
positron emission tomography
synaptic density
vascular imaging
FDG
PET/CT
microvasculature imaging
ABC-transporter
drug-induced liver injury
hepatotoxicity
organic anion-transporting polypeptide
pharmacokinetics
liver function
SLC-transporter
V/Q PET/CT
[68Ga]Ga-MAA
68Ga-labelled carbon nanoparticles
glioblastoma
fluorescence guided surgery
5-ALA
fluorescein
NIR-AZA
magnetic resonance imaging
high resolution
hybrid imaging
psychiatric disorders
extracellular vesicles (EVs)
umbilical cord mesenchymal stem cell (UCMSC)
diabetes
I-124
positron emission tomography (PET)
intravenous (I.V.) administration
intra-arterial (I.A.) administration
biodistribution
fluorine-18
PET
oxime
PSMA
lipophilicity
radiometals
copper-61
liquid targets
post-processing
[61Cu]Cu-DOTA-NOC
[61Cu]Cu-DOTA-TOC
[61Cu]Cu-DOTA-TATE
FAP
99mTc-FAP inhibitor
99mTc-labeled iFAP
tumor microenvironment
SPECT
GluN1/2B receptors
NMDA
[3H]ifenprodil
σ1 and σ2 receptors
receptor occupancy
PET imaging
drug development
neurodegenerative diseases
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20230623_9783036573915_26