Advanced Research on Animal Venoms in China
Recently, Chinese researchers have made significant progress in animal venom research in comprehending the diversity and complexity of these molecules and their potential applications in medicine, biotechnology, and as research tools. Advancements in 'omics' technologies such as proteomics, genomics...
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| Formato: | Online |
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| Idioma: | inglês |
| Publicado em: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Acesso em linha: | ONIX_20230623_9783036574349_40 |
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| _version_ | 1869525002856955904 |
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| collection | Directory of Open Access Books |
| description | Recently, Chinese researchers have made significant progress in animal venom research in comprehending the diversity and complexity of these molecules and their potential applications in medicine, biotechnology, and as research tools. Advancements in 'omics' technologies such as proteomics, genomics, and transcriptomics have empowered Chinese researchers to identify and analyze venom-coded genes and proteins, revealing a kaleidoscope of novel peptide toxins with diverse functions and activities. The reprint focus on the perspective on some of the most recent and dynamic contributions of animal toxins research by Chinese researchers. The purpose of this reprint is to provide the latest work by Chinese researchers on the discovery of animal toxins, the mechanism underlining their actions, the mining of drug leads from peptide toxins, and the diagnosis and treatment of bites or stings by venomous animals. |
| format | Online |
| id | doab-20.500.12854ir-100808 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1008082024-03-31T13:08:16Z Advanced Research on Animal Venoms in China Lai, Ren Lu, Qiumin lung cancer antimicrobial peptide scorpion venom tumor Pyemotes genome annotation protein toxin scorpion venom antimicrobial peptides Scorpio maurus palmatus Smp24 A549 apoptosis autophagy necrosis cell cycle arrest Captive Chinese cobra Ontogeny Snake venom Proteomics Transcriptomics intraspecific differentiation Mesobuthus martensii sexual dimorphism transcriptome antitumor peptide membrane disruption mitochondrial dysfunction frogs peptides skin wounds HSF cells HUVEC cells voltage-gated sodium channel Nav1.4 Nav1.5 analgesic-antitumor peptide subtype selectivity adverse drug reaction molecular dynamics neurotoxicity myotoxicity Russell’s viper Daboia siamensis Varespladib antivenom tree frogs skin secretion paxilline KCNK18 defensive strategy pore-forming toxin red-belly toad Bombina maxima hippocampal neuronal cell pyroptosis cognitive function n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology Recently, Chinese researchers have made significant progress in animal venom research in comprehending the diversity and complexity of these molecules and their potential applications in medicine, biotechnology, and as research tools. Advancements in 'omics' technologies such as proteomics, genomics, and transcriptomics have empowered Chinese researchers to identify and analyze venom-coded genes and proteins, revealing a kaleidoscope of novel peptide toxins with diverse functions and activities. The reprint focus on the perspective on some of the most recent and dynamic contributions of animal toxins research by Chinese researchers. The purpose of this reprint is to provide the latest work by Chinese researchers on the discovery of animal toxins, the mechanism underlining their actions, the mining of drug leads from peptide toxins, and the diagnosis and treatment of bites or stings by venomous animals. 2023-06-23T09:44:21Z 2023-06-23T09:44:21Z 2023 book ONIX_20230623_9783036574349_40 9783036574349 9783036574356 https://directory.doabooks.org/handle/20.500.12854/100808 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7271 https://mdpi.com/books/pdfview/book/7271 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-7435-6 10.3390/books978-3-0365-7435-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036574349 9783036574356 210 Basel open access |
| spellingShingle | lung cancer antimicrobial peptide scorpion venom tumor Pyemotes genome annotation protein toxin scorpion venom antimicrobial peptides Scorpio maurus palmatus Smp24 A549 apoptosis autophagy necrosis cell cycle arrest Captive Chinese cobra Ontogeny Snake venom Proteomics Transcriptomics intraspecific differentiation Mesobuthus martensii sexual dimorphism transcriptome antitumor peptide membrane disruption mitochondrial dysfunction frogs peptides skin wounds HSF cells HUVEC cells voltage-gated sodium channel Nav1.4 Nav1.5 analgesic-antitumor peptide subtype selectivity adverse drug reaction molecular dynamics neurotoxicity myotoxicity Russell’s viper Daboia siamensis Varespladib antivenom tree frogs skin secretion paxilline KCNK18 defensive strategy pore-forming toxin red-belly toad Bombina maxima hippocampal neuronal cell pyroptosis cognitive function n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology Advanced Research on Animal Venoms in China |
| title | Advanced Research on Animal Venoms in China |
| title_full | Advanced Research on Animal Venoms in China |
| title_fullStr | Advanced Research on Animal Venoms in China |
| title_full_unstemmed | Advanced Research on Animal Venoms in China |
| title_short | Advanced Research on Animal Venoms in China |
| title_sort | advanced research on animal venoms in china |
| topic | lung cancer antimicrobial peptide scorpion venom tumor Pyemotes genome annotation protein toxin scorpion venom antimicrobial peptides Scorpio maurus palmatus Smp24 A549 apoptosis autophagy necrosis cell cycle arrest Captive Chinese cobra Ontogeny Snake venom Proteomics Transcriptomics intraspecific differentiation Mesobuthus martensii sexual dimorphism transcriptome antitumor peptide membrane disruption mitochondrial dysfunction frogs peptides skin wounds HSF cells HUVEC cells voltage-gated sodium channel Nav1.4 Nav1.5 analgesic-antitumor peptide subtype selectivity adverse drug reaction molecular dynamics neurotoxicity myotoxicity Russell’s viper Daboia siamensis Varespladib antivenom tree frogs skin secretion paxilline KCNK18 defensive strategy pore-forming toxin red-belly toad Bombina maxima hippocampal neuronal cell pyroptosis cognitive function n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology |
| topic_facet | lung cancer antimicrobial peptide scorpion venom tumor Pyemotes genome annotation protein toxin scorpion venom antimicrobial peptides Scorpio maurus palmatus Smp24 A549 apoptosis autophagy necrosis cell cycle arrest Captive Chinese cobra Ontogeny Snake venom Proteomics Transcriptomics intraspecific differentiation Mesobuthus martensii sexual dimorphism transcriptome antitumor peptide membrane disruption mitochondrial dysfunction frogs peptides skin wounds HSF cells HUVEC cells voltage-gated sodium channel Nav1.4 Nav1.5 analgesic-antitumor peptide subtype selectivity adverse drug reaction molecular dynamics neurotoxicity myotoxicity Russell’s viper Daboia siamensis Varespladib antivenom tree frogs skin secretion paxilline KCNK18 defensive strategy pore-forming toxin red-belly toad Bombina maxima hippocampal neuronal cell pyroptosis cognitive function n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology::MKGT Medical toxicology |
| url | ONIX_20230623_9783036574349_40 |