Translational Aspects of Cardiovascular Biology
This reprint, edited by Prof. Gaetano Santulli, MD, PhD, collects the most up-to-date peer-reviewed scientific papers dealing with cardiovascular medicine, from basic science to pre-clinical and clinical investigations, highlighting the fundamental importance of translational medicine in the challen...
Wedi'i Gadw mewn:
| Fformat: | Online |
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| Iaith: | Saesneg |
| Cyhoeddwyd: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Pynciau: | |
| Mynediad Ar-lein: | ONIX_20230623_9783036575759_61 |
| Tagiau: |
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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| _version_ | 1869527455538085888 |
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| collection | Directory of Open Access Books |
| description | This reprint, edited by Prof. Gaetano Santulli, MD, PhD, collects the most up-to-date peer-reviewed scientific papers dealing with cardiovascular medicine, from basic science to pre-clinical and clinical investigations, highlighting the fundamental importance of translational medicine in the challenging quest for new therapies to cure cardiovascular disease. Indeed, cardiovascular disease is the leading cause of death worldwide, and the search for novel mechanisms and therapeutics is desperately needed. Therefore, both basic and translational studies in the cardiovascular field represent a paramount strategy to identify novel therapeutic targets and improve the quality of life of patients with cardiovascular disorders. |
| format | Online |
| id | doab-20.500.12854ir-100829 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1008292024-03-31T13:11:20Z Translational Aspects of Cardiovascular Biology Santulli, Gaetano cardiovascular disease vaccine clinical trials translational medicine atherosclerosis oxLDL phosphorylcholine RBP-4 insulin resistance severity of CAD T2D atherosclerotic CAD endothelial dysfunction hypoxia HIF-1α mitochondria oxidative stress inflammation cardiovascular diseases cancer therapeutic target extracellular NAD+ metabolism extracellular NMN metabolism vascular endothelial cells CD38 CD73 myocardial infarction neuregulin glial growth factor 2 pre-clinical therapy skeletal muscle gene expression RNA sequencing inflammatory bowel disease limb ischemia endothelial function ROS acute myocardial infarction diabetes lactic acid carbonic anhydrase CD34 endothelial cells ERG hypothermic oxygenated perfusion liver transplantation machine perfusion nestin VEGFR IDH1 foam cell macrophage ferroptosis NRF2 atrial fibrillation obesity immune infiltration biomarkers cardiac fibrosis lncRNAs TGF-β ECMs exosome red blood cells chemotherapy anemia microcirculation laser diffraction osmotic fragility test microfluidics valvular heart disease degenerative aortic valve stenosis irisin periostin osteoglycin IL-18 HMGB-1 PCSK9 blood–brain barrier blood pressure cerebrovascular disease hBMECs hypertension HUVEC microRNA miRNA miR-4432-3p n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJD Cardiovascular medicine This reprint, edited by Prof. Gaetano Santulli, MD, PhD, collects the most up-to-date peer-reviewed scientific papers dealing with cardiovascular medicine, from basic science to pre-clinical and clinical investigations, highlighting the fundamental importance of translational medicine in the challenging quest for new therapies to cure cardiovascular disease. Indeed, cardiovascular disease is the leading cause of death worldwide, and the search for novel mechanisms and therapeutics is desperately needed. Therefore, both basic and translational studies in the cardiovascular field represent a paramount strategy to identify novel therapeutic targets and improve the quality of life of patients with cardiovascular disorders. 2023-06-23T09:46:09Z 2023-06-23T09:46:09Z 2023 book ONIX_20230623_9783036575759_61 9783036575759 9783036575742 https://directory.doabooks.org/handle/20.500.12854/100829 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7292 https://mdpi.com/books/pdfview/book/7292 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-7574-2 10.3390/books978-3-0365-7574-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036575759 9783036575742 240 Basel open access |
| spellingShingle | cardiovascular disease vaccine clinical trials translational medicine atherosclerosis oxLDL phosphorylcholine RBP-4 insulin resistance severity of CAD T2D atherosclerotic CAD endothelial dysfunction hypoxia HIF-1α mitochondria oxidative stress inflammation cardiovascular diseases cancer therapeutic target extracellular NAD+ metabolism extracellular NMN metabolism vascular endothelial cells CD38 CD73 myocardial infarction neuregulin glial growth factor 2 pre-clinical therapy skeletal muscle gene expression RNA sequencing inflammatory bowel disease limb ischemia endothelial function ROS acute myocardial infarction diabetes lactic acid carbonic anhydrase CD34 endothelial cells ERG hypothermic oxygenated perfusion liver transplantation machine perfusion nestin VEGFR IDH1 foam cell macrophage ferroptosis NRF2 atrial fibrillation obesity immune infiltration biomarkers cardiac fibrosis lncRNAs TGF-β ECMs exosome red blood cells chemotherapy anemia microcirculation laser diffraction osmotic fragility test microfluidics valvular heart disease degenerative aortic valve stenosis irisin periostin osteoglycin IL-18 HMGB-1 PCSK9 blood–brain barrier blood pressure cerebrovascular disease hBMECs hypertension HUVEC microRNA miRNA miR-4432-3p n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJD Cardiovascular medicine Translational Aspects of Cardiovascular Biology |
| title | Translational Aspects of Cardiovascular Biology |
| title_full | Translational Aspects of Cardiovascular Biology |
| title_fullStr | Translational Aspects of Cardiovascular Biology |
| title_full_unstemmed | Translational Aspects of Cardiovascular Biology |
| title_short | Translational Aspects of Cardiovascular Biology |
| title_sort | translational aspects of cardiovascular biology |
| topic | cardiovascular disease vaccine clinical trials translational medicine atherosclerosis oxLDL phosphorylcholine RBP-4 insulin resistance severity of CAD T2D atherosclerotic CAD endothelial dysfunction hypoxia HIF-1α mitochondria oxidative stress inflammation cardiovascular diseases cancer therapeutic target extracellular NAD+ metabolism extracellular NMN metabolism vascular endothelial cells CD38 CD73 myocardial infarction neuregulin glial growth factor 2 pre-clinical therapy skeletal muscle gene expression RNA sequencing inflammatory bowel disease limb ischemia endothelial function ROS acute myocardial infarction diabetes lactic acid carbonic anhydrase CD34 endothelial cells ERG hypothermic oxygenated perfusion liver transplantation machine perfusion nestin VEGFR IDH1 foam cell macrophage ferroptosis NRF2 atrial fibrillation obesity immune infiltration biomarkers cardiac fibrosis lncRNAs TGF-β ECMs exosome red blood cells chemotherapy anemia microcirculation laser diffraction osmotic fragility test microfluidics valvular heart disease degenerative aortic valve stenosis irisin periostin osteoglycin IL-18 HMGB-1 PCSK9 blood–brain barrier blood pressure cerebrovascular disease hBMECs hypertension HUVEC microRNA miRNA miR-4432-3p n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJD Cardiovascular medicine |
| topic_facet | cardiovascular disease vaccine clinical trials translational medicine atherosclerosis oxLDL phosphorylcholine RBP-4 insulin resistance severity of CAD T2D atherosclerotic CAD endothelial dysfunction hypoxia HIF-1α mitochondria oxidative stress inflammation cardiovascular diseases cancer therapeutic target extracellular NAD+ metabolism extracellular NMN metabolism vascular endothelial cells CD38 CD73 myocardial infarction neuregulin glial growth factor 2 pre-clinical therapy skeletal muscle gene expression RNA sequencing inflammatory bowel disease limb ischemia endothelial function ROS acute myocardial infarction diabetes lactic acid carbonic anhydrase CD34 endothelial cells ERG hypothermic oxygenated perfusion liver transplantation machine perfusion nestin VEGFR IDH1 foam cell macrophage ferroptosis NRF2 atrial fibrillation obesity immune infiltration biomarkers cardiac fibrosis lncRNAs TGF-β ECMs exosome red blood cells chemotherapy anemia microcirculation laser diffraction osmotic fragility test microfluidics valvular heart disease degenerative aortic valve stenosis irisin periostin osteoglycin IL-18 HMGB-1 PCSK9 blood–brain barrier blood pressure cerebrovascular disease hBMECs hypertension HUVEC microRNA miRNA miR-4432-3p n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJD Cardiovascular medicine |
| url | ONIX_20230623_9783036575759_61 |