Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0

Arthritis has a high prevalence globally and includes over 100 types, the most common of which are rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and inflammatory arthritis. All types of arthritis share common features of the disease, including monocyte infiltration, inflammation, synovi...

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書誌詳細
フォーマット:	Online
言語:	英語
出版事項:	MDPI - Multidisciplinary Digital Publishing Institute 2023
主題:	rheumatoid arthritis exercise therapy autoimmune disorder treadmill running exercise articular cartilage collagen-induced arthritis pro-inflammatory cytokine connexin 43 osteoporosis microenvironment inflammation mesenchymal stem/stromal cells bone injury repair/regeneration microparticles joint inflammatory diseases Wnt signaling Dkk-1 biologics ankylosing spondylitis axial spondyloarthritis bone homeostasis osteoarthritis aging PTOA gene expression RNA-seq cartilage degeneration scRNA-seq chondrocytes animal model pain melatonin angiotensin II arthritis bone erosion tumor necrosis factor renin-angiotensin system angiotensin II type 1 receptor psoriatic arthritis osteoclastogenesis miR-941 WNT16 polymorphism genetic predisposition mutation methotrexate interleukin targeted therapy interstitial lung disease subclinical involvement ACPA pulmonary function testing CPET surfactant protein D DLCO HRCT lymph node stromal cells tolerance autoimmunity citrullination macrophages PADI2 inflammatory cytokines adhesion apoptosis L5 macrophage foam cell CD11c expression atherosclerosis rheumatoid arthritis (RA) synovium cytokines HHV-7 PCR ELISA immunohistochemistry adipocyte infrapatellar fat pad anterior cruciate ligament cartilage whole transcriptome sequencing biomarker CRISPR/Cas9 miRNA genome editing autoimmune arthritis Nkx2-3 B cell activation Spondyloarthritis ankylosing arthritis interleukin-17 interleukin-23 tibial compression gut microbiome antibiotics LPS adults juvenile immune laser blood irradiation low-level laser systemic naïve rheumatoid arthritis CD4+ T-lymphocytes methotrexate response IFNγ, IL-17A STAT expression osteonecrosis taurine mitochondrial function glucocorticoid discoidin domain receptors 1 (Ddr1) osteoarthritis (OA) autophagy terminal differentiation Treg Th17 microRNA transcriptional factor JAK/STAT Janus kinase inhibitors cardiovascular system heart failure thromboembolic lipid profile disturbances treatment molecular mechanisms biomarkers prevention collagen triple helix repeat containing 1 CTHRC1 cartilage destruction fibroblast-like synoviocytes thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
オンライン･アクセス:	ONIX_20230623_9783036575926_107
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Research of Pathogenesis and Novel Therapeutics in Arthritis 2.0

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