Cytogenetics of Domestic Animals: Clinical, Molecular and Evolutionary Aspects
The present Special Issue refers to the last 30 years of contributions to the application of cytogenetics to domestic animals, as clearly reported in the five-paper review. In addition, eight original contributions regarding the cytogenetics of several animal species are included. In each contributi...
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| Μορφή: | Online |
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| Γλώσσα: | Αγγλικά |
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MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Διαθέσιμο Online: | ONIX_20230714_9783036575889_2 |
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| description | The present Special Issue refers to the last 30 years of contributions to the application of cytogenetics to domestic animals, as clearly reported in the five-paper review. In addition, eight original contributions regarding the cytogenetics of several animal species are included. In each contribution, several thematic areas and various cytogenetic techniques are proposed to better demonstrate the potentiality of this biological technology in the genetic improvement of livestock. Special attention was paid to the presence of chromosomal abnormalities in domestic animals and their effects on reproduction, suggesting the routine use of karyotype analyses on reproducers to drastically reduce the effects on reproduction and the economic losses encountered by breeders. In addition to classical cytogenetic analyses such as chromosome banding, the use of molecular cytogenetics, especially the FISH mapping technique, with both specific molecular markers (generally BAC clones) and chromosome painting probes were emphasized in all papers to better study the following: (a) Chromosomal abnormalities; (b) The chromosomal evolution of species; (c) Physical gene mapping in light of genomic sequences in the most important domestic species. Finally, a specific review is dedicated to molecular cytogenetics, in which examples of applied molecular techniques, including the FISH technique, comparative genomic hybridization array, and PCR-based method, are reported. |
| format | Online |
| id | doab-20.500.12854ir-101303 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1013032024-03-28T03:30:37Z Cytogenetics of Domestic Animals: Clinical, Molecular and Evolutionary Aspects Iannuzzi, Leopoldo Parma, Pietro chromosome abnormality cattle river buffalo sheep goat fertility horse chromosome aberration aneuploidy translocation structural rearrangements sex reversal chimerism molecular cytogenetics FISH CGH cancer cytogenetics centric fusion disorder of sex development freemartinism intersexualism mosaicism reciprocal translocation clinical cytogenetics genomics domestic pig Thraupidae micro and macrochromosomes inter and intrachromosomal rearrangements genetic organization SSRs BAC mapping comparative cytogenetics chromosome fission chromosome fusion genome assembly karyotype karyotyping STR genotyping parental origin congenital abnormalities neurologic disorders Down syndrome Pony of Esperia chromosome instability (CIN) intestinal strongylosis eggs per gram (EPG) chromosome aberrations (CAs) endogenous retrovirus FISH-mapping cytogenetic map intersexuality XX/XY chimerism SOX9 SRY AMELX AMELY ZFX ZFY chromosomal abnormalities genomic prevalence SNP-array cytogenetics small supernumerary marker chromosome sSMC laser microdissection heterochromatin NOR Asian elephant savanna elephant animal cytogenetics FISH mapping PCR thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences The present Special Issue refers to the last 30 years of contributions to the application of cytogenetics to domestic animals, as clearly reported in the five-paper review. In addition, eight original contributions regarding the cytogenetics of several animal species are included. In each contribution, several thematic areas and various cytogenetic techniques are proposed to better demonstrate the potentiality of this biological technology in the genetic improvement of livestock. Special attention was paid to the presence of chromosomal abnormalities in domestic animals and their effects on reproduction, suggesting the routine use of karyotype analyses on reproducers to drastically reduce the effects on reproduction and the economic losses encountered by breeders. In addition to classical cytogenetic analyses such as chromosome banding, the use of molecular cytogenetics, especially the FISH mapping technique, with both specific molecular markers (generally BAC clones) and chromosome painting probes were emphasized in all papers to better study the following: (a) Chromosomal abnormalities; (b) The chromosomal evolution of species; (c) Physical gene mapping in light of genomic sequences in the most important domestic species. Finally, a specific review is dedicated to molecular cytogenetics, in which examples of applied molecular techniques, including the FISH technique, comparative genomic hybridization array, and PCR-based method, are reported. 2023-07-14T14:22:45Z 2023-07-14T14:22:45Z 2023 book ONIX_20230714_9783036575889_2 9783036575889 9783036575896 https://directory.doabooks.org/handle/20.500.12854/101303 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7396 https://mdpi.com/books/pdfview/book/7396 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-7589-6 10.3390/books978-3-0365-7589-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036575889 9783036575896 232 Basel open access |
| spellingShingle | chromosome abnormality cattle river buffalo sheep goat fertility horse chromosome aberration aneuploidy translocation structural rearrangements sex reversal chimerism molecular cytogenetics FISH CGH cancer cytogenetics centric fusion disorder of sex development freemartinism intersexualism mosaicism reciprocal translocation clinical cytogenetics genomics domestic pig Thraupidae micro and macrochromosomes inter and intrachromosomal rearrangements genetic organization SSRs BAC mapping comparative cytogenetics chromosome fission chromosome fusion genome assembly karyotype karyotyping STR genotyping parental origin congenital abnormalities neurologic disorders Down syndrome Pony of Esperia chromosome instability (CIN) intestinal strongylosis eggs per gram (EPG) chromosome aberrations (CAs) endogenous retrovirus FISH-mapping cytogenetic map intersexuality XX/XY chimerism SOX9 SRY AMELX AMELY ZFX ZFY chromosomal abnormalities genomic prevalence SNP-array cytogenetics small supernumerary marker chromosome sSMC laser microdissection heterochromatin NOR Asian elephant savanna elephant animal cytogenetics FISH mapping PCR thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Cytogenetics of Domestic Animals: Clinical, Molecular and Evolutionary Aspects |
| title | Cytogenetics of Domestic Animals: Clinical, Molecular and Evolutionary Aspects |
| title_full | Cytogenetics of Domestic Animals: Clinical, Molecular and Evolutionary Aspects |
| title_fullStr | Cytogenetics of Domestic Animals: Clinical, Molecular and Evolutionary Aspects |
| title_full_unstemmed | Cytogenetics of Domestic Animals: Clinical, Molecular and Evolutionary Aspects |
| title_short | Cytogenetics of Domestic Animals: Clinical, Molecular and Evolutionary Aspects |
| title_sort | cytogenetics of domestic animals clinical molecular and evolutionary aspects |
| topic | chromosome abnormality cattle river buffalo sheep goat fertility horse chromosome aberration aneuploidy translocation structural rearrangements sex reversal chimerism molecular cytogenetics FISH CGH cancer cytogenetics centric fusion disorder of sex development freemartinism intersexualism mosaicism reciprocal translocation clinical cytogenetics genomics domestic pig Thraupidae micro and macrochromosomes inter and intrachromosomal rearrangements genetic organization SSRs BAC mapping comparative cytogenetics chromosome fission chromosome fusion genome assembly karyotype karyotyping STR genotyping parental origin congenital abnormalities neurologic disorders Down syndrome Pony of Esperia chromosome instability (CIN) intestinal strongylosis eggs per gram (EPG) chromosome aberrations (CAs) endogenous retrovirus FISH-mapping cytogenetic map intersexuality XX/XY chimerism SOX9 SRY AMELX AMELY ZFX ZFY chromosomal abnormalities genomic prevalence SNP-array cytogenetics small supernumerary marker chromosome sSMC laser microdissection heterochromatin NOR Asian elephant savanna elephant animal cytogenetics FISH mapping PCR thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | chromosome abnormality cattle river buffalo sheep goat fertility horse chromosome aberration aneuploidy translocation structural rearrangements sex reversal chimerism molecular cytogenetics FISH CGH cancer cytogenetics centric fusion disorder of sex development freemartinism intersexualism mosaicism reciprocal translocation clinical cytogenetics genomics domestic pig Thraupidae micro and macrochromosomes inter and intrachromosomal rearrangements genetic organization SSRs BAC mapping comparative cytogenetics chromosome fission chromosome fusion genome assembly karyotype karyotyping STR genotyping parental origin congenital abnormalities neurologic disorders Down syndrome Pony of Esperia chromosome instability (CIN) intestinal strongylosis eggs per gram (EPG) chromosome aberrations (CAs) endogenous retrovirus FISH-mapping cytogenetic map intersexuality XX/XY chimerism SOX9 SRY AMELX AMELY ZFX ZFY chromosomal abnormalities genomic prevalence SNP-array cytogenetics small supernumerary marker chromosome sSMC laser microdissection heterochromatin NOR Asian elephant savanna elephant animal cytogenetics FISH mapping PCR thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20230714_9783036575889_2 |