Marine Natural Products as Anticancer Agents 2.0
Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of n...
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| Формат: | Online |
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| Язык: | английский |
| Опубликовано: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Предметы: | |
| Online-ссылка: | ONIX_20230714_9783036575681_44 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
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| _version_ | 1869515516732768256 |
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| collection | Directory of Open Access Books |
| description | Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, “Marine Natural Products as Anticancer Agents 2.0”, gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents. |
| format | Online |
| id | doab-20.500.12854ir-101345 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1013452024-03-31T13:08:08Z Marine Natural Products as Anticancer Agents 2.0 Alves, Celso Diederich, Marc Clavatadine C spirocyclic bromotyrosines cytotoxicity cancer selectivity marine compounds melanoma A-375 cell line Sarcophyton convolutum sarcoconvolutum A–E cembrenoids anti-angiogenesis bromophenols tube formation vasculogenic mimicry brefeldin A ester derivative chronic myelogenous leukemia BCR-ABL proliferation inhibition molecular modeling 5-O-(N-Boc-l-alanine)-renieramycin T Xestospongia sp. marine sponge lung cancer anti-cancer cancer stem cells apoptosis Akt c-Myc migrastatics cell migration cell invasion metastasis terpenes algae marine natural products mitochondrial dysfunction oxidative stress anticancer Sphaerococcus coronopifolius seaweed Laminaria japonica Laminaria japonica peptides cancer liver cell cycle porphyrin Isabela hemin X-ray diffraction NOESY NMR cytotoxic colorectal cancer 5-fluorouracil 7S,15R-dihydroxy-16S,17S-epoxy-docosapentaenoic acid tumor-associated macrophages chemoresistance fucoidan immunopotentiation immunomodulatory immunotherapy cancer treatment cytokines n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, “Marine Natural Products as Anticancer Agents 2.0”, gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents. 2023-07-14T14:25:44Z 2023-07-14T14:25:44Z 2023 book ONIX_20230714_9783036575681_44 9783036575681 9783036575698 https://directory.doabooks.org/handle/20.500.12854/101345 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7440 https://mdpi.com/books/pdfview/book/7440 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-7569-8 10.3390/books978-3-0365-7569-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036575681 9783036575698 212 Basel open access |
| spellingShingle | Clavatadine C spirocyclic bromotyrosines cytotoxicity cancer selectivity marine compounds melanoma A-375 cell line Sarcophyton convolutum sarcoconvolutum A–E cembrenoids anti-angiogenesis bromophenols tube formation vasculogenic mimicry brefeldin A ester derivative chronic myelogenous leukemia BCR-ABL proliferation inhibition molecular modeling 5-O-(N-Boc-l-alanine)-renieramycin T Xestospongia sp. marine sponge lung cancer anti-cancer cancer stem cells apoptosis Akt c-Myc migrastatics cell migration cell invasion metastasis terpenes algae marine natural products mitochondrial dysfunction oxidative stress anticancer Sphaerococcus coronopifolius seaweed Laminaria japonica Laminaria japonica peptides cancer liver cell cycle porphyrin Isabela hemin X-ray diffraction NOESY NMR cytotoxic colorectal cancer 5-fluorouracil 7S,15R-dihydroxy-16S,17S-epoxy-docosapentaenoic acid tumor-associated macrophages chemoresistance fucoidan immunopotentiation immunomodulatory immunotherapy cancer treatment cytokines n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology Marine Natural Products as Anticancer Agents 2.0 |
| title | Marine Natural Products as Anticancer Agents 2.0 |
| title_full | Marine Natural Products as Anticancer Agents 2.0 |
| title_fullStr | Marine Natural Products as Anticancer Agents 2.0 |
| title_full_unstemmed | Marine Natural Products as Anticancer Agents 2.0 |
| title_short | Marine Natural Products as Anticancer Agents 2.0 |
| title_sort | marine natural products as anticancer agents 2 0 |
| topic | Clavatadine C spirocyclic bromotyrosines cytotoxicity cancer selectivity marine compounds melanoma A-375 cell line Sarcophyton convolutum sarcoconvolutum A–E cembrenoids anti-angiogenesis bromophenols tube formation vasculogenic mimicry brefeldin A ester derivative chronic myelogenous leukemia BCR-ABL proliferation inhibition molecular modeling 5-O-(N-Boc-l-alanine)-renieramycin T Xestospongia sp. marine sponge lung cancer anti-cancer cancer stem cells apoptosis Akt c-Myc migrastatics cell migration cell invasion metastasis terpenes algae marine natural products mitochondrial dysfunction oxidative stress anticancer Sphaerococcus coronopifolius seaweed Laminaria japonica Laminaria japonica peptides cancer liver cell cycle porphyrin Isabela hemin X-ray diffraction NOESY NMR cytotoxic colorectal cancer 5-fluorouracil 7S,15R-dihydroxy-16S,17S-epoxy-docosapentaenoic acid tumor-associated macrophages chemoresistance fucoidan immunopotentiation immunomodulatory immunotherapy cancer treatment cytokines n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| topic_facet | Clavatadine C spirocyclic bromotyrosines cytotoxicity cancer selectivity marine compounds melanoma A-375 cell line Sarcophyton convolutum sarcoconvolutum A–E cembrenoids anti-angiogenesis bromophenols tube formation vasculogenic mimicry brefeldin A ester derivative chronic myelogenous leukemia BCR-ABL proliferation inhibition molecular modeling 5-O-(N-Boc-l-alanine)-renieramycin T Xestospongia sp. marine sponge lung cancer anti-cancer cancer stem cells apoptosis Akt c-Myc migrastatics cell migration cell invasion metastasis terpenes algae marine natural products mitochondrial dysfunction oxidative stress anticancer Sphaerococcus coronopifolius seaweed Laminaria japonica Laminaria japonica peptides cancer liver cell cycle porphyrin Isabela hemin X-ray diffraction NOESY NMR cytotoxic colorectal cancer 5-fluorouracil 7S,15R-dihydroxy-16S,17S-epoxy-docosapentaenoic acid tumor-associated macrophages chemoresistance fucoidan immunopotentiation immunomodulatory immunotherapy cancer treatment cytokines n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| url | ONIX_20230714_9783036575681_44 |