Young-Onset GI Cancer

In the last decade, the incidence of cancer in young patients has increased in several cancer types according to the US Surveillance, Epidemiology and End Result (SEER) data and other worldwide registries. Recently, Sung and colleagues published an extensive pooled analysis from the US in Lancet Pub...

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Cyhoeddwyd: MDPI - Multidisciplinary Digital Publishing Institute 2023
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Mynediad Ar-lein:ONIX_20230714_9783036579641_115
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collection Directory of Open Access Books
description In the last decade, the incidence of cancer in young patients has increased in several cancer types according to the US Surveillance, Epidemiology and End Result (SEER) data and other worldwide registries. Recently, Sung and colleagues published an extensive pooled analysis from the US in Lancet Public Health, which revealed a dramatic increase in cancer incidence among younger adults (aged 25–49 years), mainly in “obesity-related” cancers, most of which occur in the gastrointestinal (GI) tract. Several studies over the past decade have indicated a significant increase in colorectal cancer incidence among young adults below the age of 50 years. Current evidence suggests that the majority of early-onset GI cancers are sporadic and harbor no familial etiology, indicating the potentially significant role of environmental and behavioral factors in their pathogenesis. Furthermore, the gut microbiome has been proposed to play a key role in CRC carcinogenesis. The scope of this Special Issue of Cancers is to highlight perspectives regarding biology, etiology, late-term toxicities and quality of life which are unique and relevant to young-onset GI cancer cases.
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institution Directory of Open Access Books
language eng
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1014162024-03-31T13:10:44Z Young-Onset GI Cancer Aharon, Irit Ben Barreto, Savio Gastric oesophagus stomach cancer outcomes epidemiology tumour gastrointestinal risk thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology In the last decade, the incidence of cancer in young patients has increased in several cancer types according to the US Surveillance, Epidemiology and End Result (SEER) data and other worldwide registries. Recently, Sung and colleagues published an extensive pooled analysis from the US in Lancet Public Health, which revealed a dramatic increase in cancer incidence among younger adults (aged 25–49 years), mainly in “obesity-related” cancers, most of which occur in the gastrointestinal (GI) tract. Several studies over the past decade have indicated a significant increase in colorectal cancer incidence among young adults below the age of 50 years. Current evidence suggests that the majority of early-onset GI cancers are sporadic and harbor no familial etiology, indicating the potentially significant role of environmental and behavioral factors in their pathogenesis. Furthermore, the gut microbiome has been proposed to play a key role in CRC carcinogenesis. The scope of this Special Issue of Cancers is to highlight perspectives regarding biology, etiology, late-term toxicities and quality of life which are unique and relevant to young-onset GI cancer cases. 2023-07-14T14:31:10Z 2023-07-14T14:31:10Z 2023 book ONIX_20230714_9783036579641_115 9783036579641 9783036579658 https://directory.doabooks.org/handle/20.500.12854/101416 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7513 https://mdpi.com/books/pdfview/book/7513 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-7965-8 10.3390/books978-3-0365-7965-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036579641 9783036579658 134 Basel open access
spellingShingle Gastric
oesophagus
stomach
cancer
outcomes
epidemiology
tumour
gastrointestinal
risk
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
Young-Onset GI Cancer
title Young-Onset GI Cancer
title_full Young-Onset GI Cancer
title_fullStr Young-Onset GI Cancer
title_full_unstemmed Young-Onset GI Cancer
title_short Young-Onset GI Cancer
title_sort young onset gi cancer
topic Gastric
oesophagus
stomach
cancer
outcomes
epidemiology
tumour
gastrointestinal
risk
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
topic_facet Gastric
oesophagus
stomach
cancer
outcomes
epidemiology
tumour
gastrointestinal
risk
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
url ONIX_20230714_9783036579641_115