New Insights into Antithrombotic Therapy for Cardio- and Cerebrovascular Disease: From Molecular Mechanisms to Clinical Application

Thrombosis is a pathophysiological phenomenon observed in acute and chronic coronary syndrome, stroke, and peripheral artery disease. Exposure of the Tissue Factor (TF) to flowing blood is followed to its binding to other coagulation factors leading to thrombin formation. Together with platelet acti...

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Dettagli Bibliografici
Natura:	Online
Lingua:	inglese
Pubblicazione:	MDPI - Multidisciplinary Digital Publishing Institute 2023
Soggetti:	P2Y12 inhibitor monotherapy percutaneous coronary intervention dual antiplatelet therapy high bleeding risk high on-treatment platelet reactivity randomized controlled trial left atrial appendage thrombus atrial fibrillation stroke oral anticoagulant cardiovascular diseases novel antithrombotic agents antiplatelet drugs anticoagulants hemostasis factor XI factor XI inhibitor thrombosis new drugs left ventricular thrombus anticoagulation anterior wall myocardial infarction dual therapy direct oral anticoagulants surface plasmon resonance metformin matrix metalloproteinase-9 plaque instability atherosclerosis cancer acute coronary syndrome (ACS) percutaneous coronary intervention (PCI) dual antiplatelet therapy (DAPT) triple antithrombotic therapy (TAT) atrial fibrillation (AF) cardiotoxicity aspirin coronary artery disease cerebrovascular disease diabetes mellitus essential thrombocythemia platelet function thromboxane gastrointestinal bleeding enteric-coated aspirin cardiovascular prevention P2Y12 inhibitors acute coronary syndrome clopidogrel prasugrel ticagrelor cangrelor selatogrel zalunfiban peripheral artery disease (PAD) antithrombotic therapy dual pathway inhibition (DPI) major adverse cardiovascular events (MACE) major adverse limb events (MALE) n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine
Accesso online:	ONIX_20230808_9783036581163_28
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