Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease

Heme oxygenase (HO)-1 is a well-known, cytoprotective enzyme, responsible for the enzymatic conversion of heme into the anti-apoptotic and antioxidant by-products, biliverdin, bilirubin and carbon monoxide. However, HO-1 also regulates responses via mechanisms that are independent of the generation...

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フォーマット: Online
言語:英語
出版事項: MDPI - Multidisciplinary Digital Publishing Institute 2023
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オンライン・アクセス:ONIX_20230808_9783036581361_61
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collection Directory of Open Access Books
description Heme oxygenase (HO)-1 is a well-known, cytoprotective enzyme, responsible for the enzymatic conversion of heme into the anti-apoptotic and antioxidant by-products, biliverdin, bilirubin and carbon monoxide. However, HO-1 also regulates responses via mechanisms that are independent of the generation of heme degradation products. The current Special Issue contains research and review articles on the effect of heme oxygenase on immune-related cellular and physiological cascades and functions including effects on innate immunity, adaptive immunity, inflammation and complement activation. A description of the role of HO-1 in immune regulation directly or via its by-products is depicted on various forms of infection, viral and bacterial, immune-mediated injury such as renal injury, allergic airway inflammation, cancer and metabolism. Thus, the current Special Issue aims to serve as a detailed, analytical and up-to-date guide of the recent advances on the immunomodulatory properties of HO-1.
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1124932024-03-30T23:21:35Z Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease Lianos, Elias Detsika, Maria G. heme oxygenase 1 immune response inflammation immune-mediated injury &nbsp thema EDItEUR::M Medicine and Nursing Heme oxygenase (HO)-1 is a well-known, cytoprotective enzyme, responsible for the enzymatic conversion of heme into the anti-apoptotic and antioxidant by-products, biliverdin, bilirubin and carbon monoxide. However, HO-1 also regulates responses via mechanisms that are independent of the generation of heme degradation products. The current Special Issue contains research and review articles on the effect of heme oxygenase on immune-related cellular and physiological cascades and functions including effects on innate immunity, adaptive immunity, inflammation and complement activation. A description of the role of HO-1 in immune regulation directly or via its by-products is depicted on various forms of infection, viral and bacterial, immune-mediated injury such as renal injury, allergic airway inflammation, cancer and metabolism. Thus, the current Special Issue aims to serve as a detailed, analytical and up-to-date guide of the recent advances on the immunomodulatory properties of HO-1. 2023-08-08T15:15:28Z 2023-08-08T15:15:28Z 2023 book ONIX_20230808_9783036581361_61 9783036581361 9783036581378 https://directory.doabooks.org/handle/20.500.12854/112493 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7608 https://mdpi.com/books/pdfview/book/7608 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8137-8 10.3390/books978-3-0365-8137-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036581361 9783036581378 220 Basel open access
spellingShingle heme oxygenase 1
immune response
inflammation
immune-mediated injury
&nbsp
thema EDItEUR::M Medicine and Nursing
Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease
title Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease
title_full Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease
title_fullStr Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease
title_full_unstemmed Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease
title_short Heme Oxygenase (HO)-1 as an Immunoregulator in Health and Disease
title_sort heme oxygenase ho 1 as an immunoregulator in health and disease
topic heme oxygenase 1
immune response
inflammation
immune-mediated injury
&nbsp
thema EDItEUR::M Medicine and Nursing
topic_facet heme oxygenase 1
immune response
inflammation
immune-mediated injury
&nbsp
thema EDItEUR::M Medicine and Nursing
url ONIX_20230808_9783036581361_61