Intervertebral Disc Regeneration II

This second volume on the subject of intervertebral disc (IVD) regeneration ranges from in vitro IVD cell culture studies on cytokines, such as TGFβ3, GDF5, GDF6, ANG1, and ANG2, to diffuse idiopathic skeletal hyperostosis (DISH) to novel advances in the diagnosis of painful discs in reports using n...

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Julkaistu: MDPI - Multidisciplinary Digital Publishing Institute 2023
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Linkit:ONIX_20230808_9783036581989_9
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collection Directory of Open Access Books
description This second volume on the subject of intervertebral disc (IVD) regeneration ranges from in vitro IVD cell culture studies on cytokines, such as TGFβ3, GDF5, GDF6, ANG1, and ANG2, to diffuse idiopathic skeletal hyperostosis (DISH) to novel advances in the diagnosis of painful discs in reports using natural language processing (NLP). This diverse issue consists of seven articles that provide a comprehensive overview of recently applied research insights. Three original articles focus on the effects of cytokines in primary cell culture. Then, two original articles report on transcriptomics data, i.e., single-cell RNA-sequencing data of in vivo rat animal models of IVD degeneration, and human prime PCR data comparing trauma versus DISH-IVDs. One original article addresses the correct diagnosis of lumbosacral transitional vertebrae (LSTV) in scoliotic patients, and another original article addresses the usage of NLP to improve the diagnosis of painful IVDs. The Special Issue is concluded with a review on the importance of the relatively recent “hot topic” of extracellular vesicles (EVs) for regenerative purposes in IVDs.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1125032024-04-11T15:11:10Z Intervertebral Disc Regeneration II Gantenbein, Benjamin tissue engineering intervertebral disc progenitor cells GDF5 GDF6 TGF&beta 3 single-cell RNA-seq nucleus pulposus progenitor cells (NPPC) diffuse idiopathic hyperostosis extracellular vesicles rat tail model scoliosis natural language processing thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology This second volume on the subject of intervertebral disc (IVD) regeneration ranges from in vitro IVD cell culture studies on cytokines, such as TGFβ3, GDF5, GDF6, ANG1, and ANG2, to diffuse idiopathic skeletal hyperostosis (DISH) to novel advances in the diagnosis of painful discs in reports using natural language processing (NLP). This diverse issue consists of seven articles that provide a comprehensive overview of recently applied research insights. Three original articles focus on the effects of cytokines in primary cell culture. Then, two original articles report on transcriptomics data, i.e., single-cell RNA-sequencing data of in vivo rat animal models of IVD degeneration, and human prime PCR data comparing trauma versus DISH-IVDs. One original article addresses the correct diagnosis of lumbosacral transitional vertebrae (LSTV) in scoliotic patients, and another original article addresses the usage of NLP to improve the diagnosis of painful IVDs. The Special Issue is concluded with a review on the importance of the relatively recent “hot topic” of extracellular vesicles (EVs) for regenerative purposes in IVDs. 2023-08-08T15:23:33Z 2023-08-08T15:23:33Z 2023 book ONIX_20230808_9783036581989_9 9783036581989 9783036581996 https://directory.doabooks.org/handle/20.500.12854/112503 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7620 https://mdpi.com/books/pdfview/book/7620 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8199-6 10.3390/books978-3-0365-8199-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036581989 9783036581996 136 Basel open access
spellingShingle tissue engineering
intervertebral disc
progenitor cells
GDF5
GDF6
TGF&beta
3
single-cell RNA-seq
nucleus pulposus progenitor cells (NPPC)
diffuse idiopathic hyperostosis
extracellular vesicles
rat tail model
scoliosis
natural language processing
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
Intervertebral Disc Regeneration II
title Intervertebral Disc Regeneration II
title_full Intervertebral Disc Regeneration II
title_fullStr Intervertebral Disc Regeneration II
title_full_unstemmed Intervertebral Disc Regeneration II
title_short Intervertebral Disc Regeneration II
title_sort intervertebral disc regeneration ii
topic tissue engineering
intervertebral disc
progenitor cells
GDF5
GDF6
TGF&beta
3
single-cell RNA-seq
nucleus pulposus progenitor cells (NPPC)
diffuse idiopathic hyperostosis
extracellular vesicles
rat tail model
scoliosis
natural language processing
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
topic_facet tissue engineering
intervertebral disc
progenitor cells
GDF5
GDF6
TGF&beta
3
single-cell RNA-seq
nucleus pulposus progenitor cells (NPPC)
diffuse idiopathic hyperostosis
extracellular vesicles
rat tail model
scoliosis
natural language processing
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
url ONIX_20230808_9783036581989_9