Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition

This reprint represents a collection of 12 scientific papers belonging to the Special Issue in International Journal of Molecular Sciences titled “Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition". Obesity is a serious global health problem with a high...

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collection Directory of Open Access Books
description This reprint represents a collection of 12 scientific papers belonging to the Special Issue in International Journal of Molecular Sciences titled “Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition". Obesity is a serious global health problem with a high incidence of mortality and morbidity. Many drivers have been identified for its etiopathogenesis, such as excessive food intake, reduced physical activity and genetic predisposition. Adipose tissue is considered an endocrine organ producing multiple immune-modulatory proteins, known as adipokines with a pro-inflammatory or anti-inflammatory nature. An unbalanced production of adipokines with a pro-inflammatory role in adipose tissue induces low-grade systemic inflammation in obese patients, which predisposes them to insulin resistance, type II diabetes, cardiovascular disorders, and cancer. Nowadays, there has been a growing interest in finding novel target compounds, both natural and synthetic, with potential action against obesity. This reprint explores the mechanisms underlying the etiopathogenesis of obesity and related diseases and aims to identify new therapeutic strategy. In particular, the reprint focuses on the role of natural and synthetic compounds for the Management, Prevention and Treatment of Obesity. We thank all the authors for their contribution to the research topic of this reprint and all editorial staff for its valuable support.
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language eng
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1125652024-03-28T03:33:54Z Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition Lauricella, Marianna D'Anneo, Antonella histamine H3 receptor ligands sigma-2 receptor ligands palatable diet excessive eating model obesity erythritol xylitol erythronate natural sweeteners absorption metabolism diabetes visceral obesity hepatic steatosis 4-methylesculetin adipose microenvironment metabolic syndrome Fascia hyaluronan fasciopathy myofascial disease pathophysiology therapeutics adenosine A2B receptor antagonist glucose tolerance metabolic disorder PSB-603 Theophylline adipose-derived stem cells epigenetics adipogenesis cellular mechanisms bariatric surgery anti-obesity drugs high-fat diet neuronal damage neurodegeneration honey D-limonene saliva body composition proinflammatory cytokines proinflammatory adipokines IL-6 IL-1β resistin MMP-9 MMP-2 hyperinsulinemia monosodium glutamate distress oxidative pro-inflammatory profile skeletal muscle fiber types mango peel extracts mango seed extracts saturated fatty acids 3T3-L1 adipocytes ER stress AMPK Nrf2 adipose tissue fibrosis IL-13 IL-4 macrophages hypoglycemia insulinoma curcumin piperine bioavailability n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This reprint represents a collection of 12 scientific papers belonging to the Special Issue in International Journal of Molecular Sciences titled “Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition". Obesity is a serious global health problem with a high incidence of mortality and morbidity. Many drivers have been identified for its etiopathogenesis, such as excessive food intake, reduced physical activity and genetic predisposition. Adipose tissue is considered an endocrine organ producing multiple immune-modulatory proteins, known as adipokines with a pro-inflammatory or anti-inflammatory nature. An unbalanced production of adipokines with a pro-inflammatory role in adipose tissue induces low-grade systemic inflammation in obese patients, which predisposes them to insulin resistance, type II diabetes, cardiovascular disorders, and cancer. Nowadays, there has been a growing interest in finding novel target compounds, both natural and synthetic, with potential action against obesity. This reprint explores the mechanisms underlying the etiopathogenesis of obesity and related diseases and aims to identify new therapeutic strategy. In particular, the reprint focuses on the role of natural and synthetic compounds for the Management, Prevention and Treatment of Obesity. We thank all the authors for their contribution to the research topic of this reprint and all editorial staff for its valuable support. 2023-08-08T15:27:56Z 2023-08-08T15:27:56Z 2023 book ONIX_20230808_9783036583488_71 9783036583488 9783036583495 https://directory.doabooks.org/handle/20.500.12854/112565 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/7691 https://mdpi.com/books/pdfview/book/7691 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8349-5 10.3390/books978-3-0365-8349-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036583488 9783036583495 224 Basel open access
spellingShingle histamine H3 receptor ligands
sigma-2 receptor ligands
palatable diet
excessive eating model
obesity
erythritol
xylitol
erythronate
natural sweeteners
absorption
metabolism
diabetes
visceral obesity
hepatic steatosis
4-methylesculetin
adipose microenvironment
metabolic syndrome
Fascia
hyaluronan
fasciopathy
myofascial disease
pathophysiology
therapeutics
adenosine A2B receptor antagonist
glucose tolerance
metabolic disorder
PSB-603
Theophylline
adipose-derived stem cells
epigenetics
adipogenesis
cellular mechanisms
bariatric surgery
anti-obesity drugs
high-fat diet
neuronal damage
neurodegeneration
honey
D-limonene
saliva
body composition
proinflammatory cytokines
proinflammatory adipokines
IL-6
IL-1β
resistin
MMP-9
MMP-2
hyperinsulinemia
monosodium glutamate
distress oxidative
pro-inflammatory profile
skeletal muscle fiber types
mango peel extracts
mango seed extracts
saturated fatty acids
3T3-L1 adipocytes
ER stress
AMPK
Nrf2
adipose tissue
fibrosis
IL-13
IL-4
macrophages
hypoglycemia
insulinoma
curcumin
piperine
bioavailability
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition
title Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition
title_full Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition
title_fullStr Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition
title_full_unstemmed Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition
title_short Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 2nd Edition
title_sort natural and synthetic compounds for management prevention and treatment of obesity 2nd edition
topic histamine H3 receptor ligands
sigma-2 receptor ligands
palatable diet
excessive eating model
obesity
erythritol
xylitol
erythronate
natural sweeteners
absorption
metabolism
diabetes
visceral obesity
hepatic steatosis
4-methylesculetin
adipose microenvironment
metabolic syndrome
Fascia
hyaluronan
fasciopathy
myofascial disease
pathophysiology
therapeutics
adenosine A2B receptor antagonist
glucose tolerance
metabolic disorder
PSB-603
Theophylline
adipose-derived stem cells
epigenetics
adipogenesis
cellular mechanisms
bariatric surgery
anti-obesity drugs
high-fat diet
neuronal damage
neurodegeneration
honey
D-limonene
saliva
body composition
proinflammatory cytokines
proinflammatory adipokines
IL-6
IL-1β
resistin
MMP-9
MMP-2
hyperinsulinemia
monosodium glutamate
distress oxidative
pro-inflammatory profile
skeletal muscle fiber types
mango peel extracts
mango seed extracts
saturated fatty acids
3T3-L1 adipocytes
ER stress
AMPK
Nrf2
adipose tissue
fibrosis
IL-13
IL-4
macrophages
hypoglycemia
insulinoma
curcumin
piperine
bioavailability
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet histamine H3 receptor ligands
sigma-2 receptor ligands
palatable diet
excessive eating model
obesity
erythritol
xylitol
erythronate
natural sweeteners
absorption
metabolism
diabetes
visceral obesity
hepatic steatosis
4-methylesculetin
adipose microenvironment
metabolic syndrome
Fascia
hyaluronan
fasciopathy
myofascial disease
pathophysiology
therapeutics
adenosine A2B receptor antagonist
glucose tolerance
metabolic disorder
PSB-603
Theophylline
adipose-derived stem cells
epigenetics
adipogenesis
cellular mechanisms
bariatric surgery
anti-obesity drugs
high-fat diet
neuronal damage
neurodegeneration
honey
D-limonene
saliva
body composition
proinflammatory cytokines
proinflammatory adipokines
IL-6
IL-1β
resistin
MMP-9
MMP-2
hyperinsulinemia
monosodium glutamate
distress oxidative
pro-inflammatory profile
skeletal muscle fiber types
mango peel extracts
mango seed extracts
saturated fatty acids
3T3-L1 adipocytes
ER stress
AMPK
Nrf2
adipose tissue
fibrosis
IL-13
IL-4
macrophages
hypoglycemia
insulinoma
curcumin
piperine
bioavailability
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20230808_9783036583488_71