Epilepsy
According to the World Health Organization, nearly 80% of people with epilepsy live in low- and middle-income countries and could live seizure-free if properly diagnosed and treated. Among the structural and genetic triggers that may lead to epilepsy are head trauma, abnormal synaptic connectivity,...
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| Formaat: | Online |
|---|---|
| Taal: | Engels |
| Gepubliceerd in: |
IntechOpen
2023
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| Onderwerpen: | |
| Online toegang: | ONIX_20230905_9781803566009_15 |
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| _version_ | 1869516299517820928 |
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| collection | Directory of Open Access Books |
| description | According to the World Health Organization, nearly 80% of people with epilepsy live in low- and middle-income countries and could live seizure-free if properly diagnosed and treated. Among the structural and genetic triggers that may lead to epilepsy are head trauma, abnormal synaptic connectivity, receptor subunits anomalies, and atypical ionic channel function. Developing brains are specifically susceptible to seizures for many reasons, for example, the presence of enhanced excitation due to the early production of excitatory neurotransmitters, and the fact that the inhibitory neurotransmitter GABA causes excitation early in life. These studies help to clarify why the very young brain is exceptionally prone to seizures. The chapters presented in this book describe how structural, genetic, infectious, and metabolic abnormalities can lead to epileptogenesis. Nevertheless, many underlying disease mechanisms that can lead to epilepsy remain unknown. |
| format | Online |
| id | doab-20.500.12854ir-113214 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1132142024-04-01T14:15:13Z Epilepsy Fatima Shad, Kaneez neuroinflammation apoptosis parasites microglia meg leukoencephalopathy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology According to the World Health Organization, nearly 80% of people with epilepsy live in low- and middle-income countries and could live seizure-free if properly diagnosed and treated. Among the structural and genetic triggers that may lead to epilepsy are head trauma, abnormal synaptic connectivity, receptor subunits anomalies, and atypical ionic channel function. Developing brains are specifically susceptible to seizures for many reasons, for example, the presence of enhanced excitation due to the early production of excitatory neurotransmitters, and the fact that the inhibitory neurotransmitter GABA causes excitation early in life. These studies help to clarify why the very young brain is exceptionally prone to seizures. The chapters presented in this book describe how structural, genetic, infectious, and metabolic abnormalities can lead to epileptogenesis. Nevertheless, many underlying disease mechanisms that can lead to epilepsy remain unknown. 2023-09-05T15:48:31Z 2023-09-05T15:48:31Z 2023 book ONIX_20230905_9781803566009_15 9781803566009 9781803565996 9781803566016 https://directory.doabooks.org/handle/20.500.12854/113214 eng image/jpeg n/a https://www.intechopen.com/books/11585 https://mts.intechopen.com/storage/books/11585/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.100833 10.5772/intechopen.100833 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781803566009 9781803565996 9781803566016 IntechOpen 118 open access |
| spellingShingle | neuroinflammation apoptosis parasites microglia meg leukoencephalopathy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology Epilepsy |
| title | Epilepsy |
| title_full | Epilepsy |
| title_fullStr | Epilepsy |
| title_full_unstemmed | Epilepsy |
| title_short | Epilepsy |
| title_sort | epilepsy |
| topic | neuroinflammation apoptosis parasites microglia meg leukoencephalopathy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology |
| topic_facet | neuroinflammation apoptosis parasites microglia meg leukoencephalopathy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology |
| url | ONIX_20230905_9781803566009_15 |