RNA Therapeutics

RNA therapies evolved as economical and widely applicable individualized treatment solutions. Novel RNA-based therapeutic vaccines (e.g., against SARS-CoV-2 infection) have been proven to be safe and effective, and many of them are approved by the United States Food and Drug Administration (FDA). Th...

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collection Directory of Open Access Books
description RNA therapies evolved as economical and widely applicable individualized treatment solutions. Novel RNA-based therapeutic vaccines (e.g., against SARS-CoV-2 infection) have been proven to be safe and effective, and many of them are approved by the United States Food and Drug Administration (FDA). This book presents distinct classes of RNA therapeutics, ranging from single-stranded antisense oligonucleotides (ASOs) and subclasses of RNA interferences (miRNAs and other RNAi) to in vitro transcribed and in vivo translated mRNAs drugs and RNA vaccines. The book also discusses some of the challenges in RNA drug engineering, delivery, and specificity, as well as highlights the improvement of pharmacological effectiveness in a wide range of diseases.
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institution Directory of Open Access Books
language eng
publishDate 2023
publishDateRange 2023
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publisher IntechOpen
publisherStr IntechOpen
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spelling doab-20.500.12854ir-1133702024-04-05T17:30:56Z RNA Therapeutics Louis, Irina Vlasova-St. cancer clinical trials covid-19 pandemic sars-cov-2 public health thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology RNA therapies evolved as economical and widely applicable individualized treatment solutions. Novel RNA-based therapeutic vaccines (e.g., against SARS-CoV-2 infection) have been proven to be safe and effective, and many of them are approved by the United States Food and Drug Administration (FDA). This book presents distinct classes of RNA therapeutics, ranging from single-stranded antisense oligonucleotides (ASOs) and subclasses of RNA interferences (miRNAs and other RNAi) to in vitro transcribed and in vivo translated mRNAs drugs and RNA vaccines. The book also discusses some of the challenges in RNA drug engineering, delivery, and specificity, as well as highlights the improvement of pharmacological effectiveness in a wide range of diseases. 2023-09-05T16:01:27Z 2023-09-05T16:01:27Z 2023 book ONIX_20230905_9781803556581_171 9781803556581 9781803556574 9781803556598 https://directory.doabooks.org/handle/20.500.12854/113370 eng image/jpeg n/a https://www.intechopen.com/books/11813 https://mts.intechopen.com/storage/books/11813/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.102166 10.5772/intechopen.102166 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781803556581 9781803556574 9781803556598 IntechOpen 138 open access
spellingShingle cancer
clinical trials
covid-19
pandemic
sars-cov-2
public health
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
RNA Therapeutics
title RNA Therapeutics
title_full RNA Therapeutics
title_fullStr RNA Therapeutics
title_full_unstemmed RNA Therapeutics
title_short RNA Therapeutics
title_sort rna therapeutics
topic cancer
clinical trials
covid-19
pandemic
sars-cov-2
public health
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
topic_facet cancer
clinical trials
covid-19
pandemic
sars-cov-2
public health
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
url ONIX_20230905_9781803556581_171