Infection, Super Infection and Antimicrobial Management in ICU

Assessing the risk of difficult-to-treat bacterial superinfections, such as multidrug-resistant (MDR) Gram-negative bacilli, according to comorbidities, lung abnormalities or systemic diseases, the severity of pneumonia and the risks of drug-related effects are crucial points for the clinical manage...

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Опубликовано: MDPI - Multidisciplinary Digital Publishing Institute 2023
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collection Directory of Open Access Books
description Assessing the risk of difficult-to-treat bacterial superinfections, such as multidrug-resistant (MDR) Gram-negative bacilli, according to comorbidities, lung abnormalities or systemic diseases, the severity of pneumonia and the risks of drug-related effects are crucial points for the clinical management. Despite the wide—and not always appropriate—use of broad-spectrum antimicrobials, specific data about bacterial and fungal co-infection in COVID-19 patients are lacking, and confirmed evidence is urgently required to build prospective evidence and to support the development of antimicrobial policy and appropriate stewardship interventions. The present Special Issue aims to focus on the following key points: Importance of superinfections in COVID-19 patients who are typically characterized by immunosuppression related to viral infection, need for prolonged hospitalization, treatment with immunomodulatory therapies (steroids, monoclonal antibodies, etc.); Their impact on the outcome of a cohort of patients who are relatively young, with few comorbidities, but requiring prolonged invasive support; Incidence, characteristics and impact of bacterial infections caused by multidrug-resistant, Gram-negative pathogens in the context of COVID-19 disease; Incidence, characteristics and impact of fungal infections, such as the most known invasive aspergillosis but also candidemia and/or other fungal infections (e.g., mucormycosis); Antimicrobial surveillance, control and management measures as implemented on a local, national and international basis.
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spelling doab-20.500.12854ir-1138672024-03-30T23:21:56Z Infection, Super Infection and Antimicrobial Management in ICU Brazzi, Luca Montrucchio, Giorgia Superinfections COVID-19 SARS-CoV-2 multidrug-resistant pathogens antimicrobial stewardship antimicrobial resistance fungal infections bacterial infections intensive care medicine critical care medicine thema EDItEUR::M Medicine and Nursing Assessing the risk of difficult-to-treat bacterial superinfections, such as multidrug-resistant (MDR) Gram-negative bacilli, according to comorbidities, lung abnormalities or systemic diseases, the severity of pneumonia and the risks of drug-related effects are crucial points for the clinical management. Despite the wide—and not always appropriate—use of broad-spectrum antimicrobials, specific data about bacterial and fungal co-infection in COVID-19 patients are lacking, and confirmed evidence is urgently required to build prospective evidence and to support the development of antimicrobial policy and appropriate stewardship interventions. The present Special Issue aims to focus on the following key points: Importance of superinfections in COVID-19 patients who are typically characterized by immunosuppression related to viral infection, need for prolonged hospitalization, treatment with immunomodulatory therapies (steroids, monoclonal antibodies, etc.); Their impact on the outcome of a cohort of patients who are relatively young, with few comorbidities, but requiring prolonged invasive support; Incidence, characteristics and impact of bacterial infections caused by multidrug-resistant, Gram-negative pathogens in the context of COVID-19 disease; Incidence, characteristics and impact of fungal infections, such as the most known invasive aspergillosis but also candidemia and/or other fungal infections (e.g., mucormycosis); Antimicrobial surveillance, control and management measures as implemented on a local, national and international basis. 2023-09-11T11:37:33Z 2023-09-11T11:37:33Z 2023 book ONIX_20230911_9783036583808_3 9783036583808 9783036583815 https://directory.doabooks.org/handle/20.500.12854/113867 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/7708 https://mdpi.com/books/pdfview/book/7708 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8381-5 10.3390/books978-3-0365-8381-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036583808 9783036583815 144 open access
spellingShingle Superinfections
COVID-19
SARS-CoV-2
multidrug-resistant pathogens
antimicrobial stewardship
antimicrobial resistance
fungal infections
bacterial infections
intensive care medicine
critical care medicine
thema EDItEUR::M Medicine and Nursing
Infection, Super Infection and Antimicrobial Management in ICU
title Infection, Super Infection and Antimicrobial Management in ICU
title_full Infection, Super Infection and Antimicrobial Management in ICU
title_fullStr Infection, Super Infection and Antimicrobial Management in ICU
title_full_unstemmed Infection, Super Infection and Antimicrobial Management in ICU
title_short Infection, Super Infection and Antimicrobial Management in ICU
title_sort infection super infection and antimicrobial management in icu
topic Superinfections
COVID-19
SARS-CoV-2
multidrug-resistant pathogens
antimicrobial stewardship
antimicrobial resistance
fungal infections
bacterial infections
intensive care medicine
critical care medicine
thema EDItEUR::M Medicine and Nursing
topic_facet Superinfections
COVID-19
SARS-CoV-2
multidrug-resistant pathogens
antimicrobial stewardship
antimicrobial resistance
fungal infections
bacterial infections
intensive care medicine
critical care medicine
thema EDItEUR::M Medicine and Nursing
url ONIX_20230911_9783036583808_3