Chronic Kidney Disease: Underlying Molecular Mechanisms
Chronic kidney disease (CKD) is a worldwide public health problem that must be addressed. The global increase in CKD prevalence is associated with an increase in conventional disease risk factors (e.g., diabetes and hypertension), which may be exacerbated by additional variables such as environmenta...
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| Format: | Online |
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| Sprog: | engelsk |
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MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Online adgang: | ONIX_20230911_9783036585413_14 |
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| _version_ | 1869530699414896640 |
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| collection | Directory of Open Access Books |
| description | Chronic kidney disease (CKD) is a worldwide public health problem that must be addressed. The global increase in CKD prevalence is associated with an increase in conventional disease risk factors (e.g., diabetes and hypertension), which may be exacerbated by additional variables such as environmental and occupational exposure to toxic compounds. Authors contributed to this Special Issue by highlighting the finding of potential novel biomarkers of the disease and more effective therapy alternatives, as well as works that enhance the understanding of CKD pathogenesis and its related complications. |
| format | Online |
| id | doab-20.500.12854ir-113881 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1138812024-03-31T13:08:14Z Chronic Kidney Disease: Underlying Molecular Mechanisms Carvalho, Márcia Belo, Luís kidney lymphatics sodium NKCC1 transporter CKD inflammation TNF-alpha TNFR biomarkers chronic kidney disease hypertension children short-chain fatty acids developmental origins of health and disease (DOHaD) gut microbiota probiotics prebiotics trimethylamine-N-oxide oxidative stress uremic toxins TRPC6 UUO NZO mice fibrosis SH045 heavy metals cadmium mercury arsenic cellular injury urine proteome FSGS MCD podocyte dysfunction mass spectrometry growth hormone cachexia lipolysis adipose tissue browning muscle mass muscle function skeletal muscle wasting reactive oxygen species (ROS) exercise Marinobufagenin (MBG) end-stage renal disease (ESRD) nervous and immune systems n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology Chronic kidney disease (CKD) is a worldwide public health problem that must be addressed. The global increase in CKD prevalence is associated with an increase in conventional disease risk factors (e.g., diabetes and hypertension), which may be exacerbated by additional variables such as environmental and occupational exposure to toxic compounds. Authors contributed to this Special Issue by highlighting the finding of potential novel biomarkers of the disease and more effective therapy alternatives, as well as works that enhance the understanding of CKD pathogenesis and its related complications. 2023-09-11T11:50:44Z 2023-09-11T11:50:44Z 2023 book ONIX_20230911_9783036585413_14 9783036585413 9783036585406 https://directory.doabooks.org/handle/20.500.12854/113881 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/7722 https://mdpi.com/books/pdfview/book/7722 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8540-6 10.3390/books978-3-0365-8540-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036585413 9783036585406 216 open access |
| spellingShingle | kidney lymphatics sodium NKCC1 transporter CKD inflammation TNF-alpha TNFR biomarkers chronic kidney disease hypertension children short-chain fatty acids developmental origins of health and disease (DOHaD) gut microbiota probiotics prebiotics trimethylamine-N-oxide oxidative stress uremic toxins TRPC6 UUO NZO mice fibrosis SH045 heavy metals cadmium mercury arsenic cellular injury urine proteome FSGS MCD podocyte dysfunction mass spectrometry growth hormone cachexia lipolysis adipose tissue browning muscle mass muscle function skeletal muscle wasting reactive oxygen species (ROS) exercise Marinobufagenin (MBG) end-stage renal disease (ESRD) nervous and immune systems n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology Chronic Kidney Disease: Underlying Molecular Mechanisms |
| title | Chronic Kidney Disease: Underlying Molecular Mechanisms |
| title_full | Chronic Kidney Disease: Underlying Molecular Mechanisms |
| title_fullStr | Chronic Kidney Disease: Underlying Molecular Mechanisms |
| title_full_unstemmed | Chronic Kidney Disease: Underlying Molecular Mechanisms |
| title_short | Chronic Kidney Disease: Underlying Molecular Mechanisms |
| title_sort | chronic kidney disease underlying molecular mechanisms |
| topic | kidney lymphatics sodium NKCC1 transporter CKD inflammation TNF-alpha TNFR biomarkers chronic kidney disease hypertension children short-chain fatty acids developmental origins of health and disease (DOHaD) gut microbiota probiotics prebiotics trimethylamine-N-oxide oxidative stress uremic toxins TRPC6 UUO NZO mice fibrosis SH045 heavy metals cadmium mercury arsenic cellular injury urine proteome FSGS MCD podocyte dysfunction mass spectrometry growth hormone cachexia lipolysis adipose tissue browning muscle mass muscle function skeletal muscle wasting reactive oxygen species (ROS) exercise Marinobufagenin (MBG) end-stage renal disease (ESRD) nervous and immune systems n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| topic_facet | kidney lymphatics sodium NKCC1 transporter CKD inflammation TNF-alpha TNFR biomarkers chronic kidney disease hypertension children short-chain fatty acids developmental origins of health and disease (DOHaD) gut microbiota probiotics prebiotics trimethylamine-N-oxide oxidative stress uremic toxins TRPC6 UUO NZO mice fibrosis SH045 heavy metals cadmium mercury arsenic cellular injury urine proteome FSGS MCD podocyte dysfunction mass spectrometry growth hormone cachexia lipolysis adipose tissue browning muscle mass muscle function skeletal muscle wasting reactive oxygen species (ROS) exercise Marinobufagenin (MBG) end-stage renal disease (ESRD) nervous and immune systems n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| url | ONIX_20230911_9783036585413_14 |