Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach
With the advancements in the medical and scientific fields, the global community has acquired a comprehensive understanding about brain insults and pathologies. In addition, new findings and discoveries are being made globally every day, which keep our curiosity high and drive a knowledge gain. Any...
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| Format: | Online |
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| Language: | English |
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MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Online Access: | ONIX_20230911_9783036583846_38 |
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| description | With the advancements in the medical and scientific fields, the global community has acquired a comprehensive understanding about brain insults and pathologies. In addition, new findings and discoveries are being made globally every day, which keep our curiosity high and drive a knowledge gain. Any brain insult or pathology is multifactorial, including a cascade of inflammation, necrotic, and apoptotic pathways; can be influenced by genetic or environmental factors; and may lead to chronic neurodegeneration or disabilities. This Special Issue, entitled “Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach”, has addressed various important aspects of brain injury and neurodegeneration, such as TBI, cerebral hypoxia, epilepsy, AD, and SARS-CoV-2-mediated brain damage. It received appreciable global response, and published 18 peer-reviewed articles, including 10 research articles and 8 reviews. Briefly, it explores the recent coronavirus infection-mediated cerebral damage; discusses the mechanism of TBI, ischemia, hypoxia, and epilepsy; talks about neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and CONDCA; and, finally, reviews the translational values of phytochemicals in brain pathologies. In conclusion, this Special Issue provides a unique review on brain injury and neurodegeneration, and will be a good tool in enhancing knowledge in terms of brain disease-related pathology, mechanisms, and translational approach. |
| format | Online |
| id | doab-20.500.12854ir-113905 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1139052024-03-31T13:08:19Z Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach Vaibhav, Kumar Ahluwalia, Meenakshi Gaur, Pankaj neurodegenerative diseases phytochemicals natural products neuroprotection neurotrauma neuroinflammation excitotoxicity oxidative stress apoptosis edema brain injury therapeutic strategies 18F-FDG PET anosmia COVID-19 SARS-CoV-2 olfactory dysfunction anti-convulsants anti-epileptic drugs drug targets epileptogenesis non-communicable disease seizures transcriptional modifications pseudo-resistance ischemia FABP3 FABP5 FABP7 mPGES-1 PGE2 treadmill exercise Parkinson’s disease neural mitochondrial functions amyloid beta Alzheimer’s disease inflammation gene regulation organelle dysfunction AGTPBP1 CCP1 CONDCA neurodegeneration NNA1 pcd microglia chronic alcoholism HHV-6 Substantia Nigra ischemic stroke epigenetics histone deacetylase histone deacetylase inhibitor mechanical stimulations traumatic brain injury (TBI) stretching neurons GSK-3β p-Tau extracellular matrix icariin icaritin middle cerebral artery occlusion traumatic brain injury blunt-force TBI post-traumatic seizures zebrafish sonic hedgehog signaling purmorphamine mild traumatic brain injury microRNA exomiRNA exosome TBI tRNA miRNA isomiR RNAseq moderate traumatic brain injury reactive oxygen species cognitive impairment mitochondria hypoxia neuraxis hypoxic-ischemic injuries neural ischemia neural tissue hypoxic injuries neuro-recovery neurorehabilitation n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology With the advancements in the medical and scientific fields, the global community has acquired a comprehensive understanding about brain insults and pathologies. In addition, new findings and discoveries are being made globally every day, which keep our curiosity high and drive a knowledge gain. Any brain insult or pathology is multifactorial, including a cascade of inflammation, necrotic, and apoptotic pathways; can be influenced by genetic or environmental factors; and may lead to chronic neurodegeneration or disabilities. This Special Issue, entitled “Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach”, has addressed various important aspects of brain injury and neurodegeneration, such as TBI, cerebral hypoxia, epilepsy, AD, and SARS-CoV-2-mediated brain damage. It received appreciable global response, and published 18 peer-reviewed articles, including 10 research articles and 8 reviews. Briefly, it explores the recent coronavirus infection-mediated cerebral damage; discusses the mechanism of TBI, ischemia, hypoxia, and epilepsy; talks about neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and CONDCA; and, finally, reviews the translational values of phytochemicals in brain pathologies. In conclusion, this Special Issue provides a unique review on brain injury and neurodegeneration, and will be a good tool in enhancing knowledge in terms of brain disease-related pathology, mechanisms, and translational approach. 2023-09-11T11:57:40Z 2023-09-11T11:57:40Z 2023 book ONIX_20230911_9783036583846_38 9783036583846 9783036583853 https://directory.doabooks.org/handle/20.500.12854/113905 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/7746 https://mdpi.com/books/pdfview/book/7746 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8385-3 10.3390/books978-3-0365-8385-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036583846 9783036583853 428 open access |
| spellingShingle | neurodegenerative diseases phytochemicals natural products neuroprotection neurotrauma neuroinflammation excitotoxicity oxidative stress apoptosis edema brain injury therapeutic strategies 18F-FDG PET anosmia COVID-19 SARS-CoV-2 olfactory dysfunction anti-convulsants anti-epileptic drugs drug targets epileptogenesis non-communicable disease seizures transcriptional modifications pseudo-resistance ischemia FABP3 FABP5 FABP7 mPGES-1 PGE2 treadmill exercise Parkinson’s disease neural mitochondrial functions amyloid beta Alzheimer’s disease inflammation gene regulation organelle dysfunction AGTPBP1 CCP1 CONDCA neurodegeneration NNA1 pcd microglia chronic alcoholism HHV-6 Substantia Nigra ischemic stroke epigenetics histone deacetylase histone deacetylase inhibitor mechanical stimulations traumatic brain injury (TBI) stretching neurons GSK-3β p-Tau extracellular matrix icariin icaritin middle cerebral artery occlusion traumatic brain injury blunt-force TBI post-traumatic seizures zebrafish sonic hedgehog signaling purmorphamine mild traumatic brain injury microRNA exomiRNA exosome TBI tRNA miRNA isomiR RNAseq moderate traumatic brain injury reactive oxygen species cognitive impairment mitochondria hypoxia neuraxis hypoxic-ischemic injuries neural ischemia neural tissue hypoxic injuries neuro-recovery neurorehabilitation n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach |
| title | Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach |
| title_full | Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach |
| title_fullStr | Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach |
| title_full_unstemmed | Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach |
| title_short | Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach |
| title_sort | brain injury and neurodegeneration molecular functional and translational approach |
| topic | neurodegenerative diseases phytochemicals natural products neuroprotection neurotrauma neuroinflammation excitotoxicity oxidative stress apoptosis edema brain injury therapeutic strategies 18F-FDG PET anosmia COVID-19 SARS-CoV-2 olfactory dysfunction anti-convulsants anti-epileptic drugs drug targets epileptogenesis non-communicable disease seizures transcriptional modifications pseudo-resistance ischemia FABP3 FABP5 FABP7 mPGES-1 PGE2 treadmill exercise Parkinson’s disease neural mitochondrial functions amyloid beta Alzheimer’s disease inflammation gene regulation organelle dysfunction AGTPBP1 CCP1 CONDCA neurodegeneration NNA1 pcd microglia chronic alcoholism HHV-6 Substantia Nigra ischemic stroke epigenetics histone deacetylase histone deacetylase inhibitor mechanical stimulations traumatic brain injury (TBI) stretching neurons GSK-3β p-Tau extracellular matrix icariin icaritin middle cerebral artery occlusion traumatic brain injury blunt-force TBI post-traumatic seizures zebrafish sonic hedgehog signaling purmorphamine mild traumatic brain injury microRNA exomiRNA exosome TBI tRNA miRNA isomiR RNAseq moderate traumatic brain injury reactive oxygen species cognitive impairment mitochondria hypoxia neuraxis hypoxic-ischemic injuries neural ischemia neural tissue hypoxic injuries neuro-recovery neurorehabilitation n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology |
| topic_facet | neurodegenerative diseases phytochemicals natural products neuroprotection neurotrauma neuroinflammation excitotoxicity oxidative stress apoptosis edema brain injury therapeutic strategies 18F-FDG PET anosmia COVID-19 SARS-CoV-2 olfactory dysfunction anti-convulsants anti-epileptic drugs drug targets epileptogenesis non-communicable disease seizures transcriptional modifications pseudo-resistance ischemia FABP3 FABP5 FABP7 mPGES-1 PGE2 treadmill exercise Parkinson’s disease neural mitochondrial functions amyloid beta Alzheimer’s disease inflammation gene regulation organelle dysfunction AGTPBP1 CCP1 CONDCA neurodegeneration NNA1 pcd microglia chronic alcoholism HHV-6 Substantia Nigra ischemic stroke epigenetics histone deacetylase histone deacetylase inhibitor mechanical stimulations traumatic brain injury (TBI) stretching neurons GSK-3β p-Tau extracellular matrix icariin icaritin middle cerebral artery occlusion traumatic brain injury blunt-force TBI post-traumatic seizures zebrafish sonic hedgehog signaling purmorphamine mild traumatic brain injury microRNA exomiRNA exosome TBI tRNA miRNA isomiR RNAseq moderate traumatic brain injury reactive oxygen species cognitive impairment mitochondria hypoxia neuraxis hypoxic-ischemic injuries neural ischemia neural tissue hypoxic injuries neuro-recovery neurorehabilitation n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology |
| url | ONIX_20230911_9783036583846_38 |