Natural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies
The chemistry of natural products is rich in diversity, which can be noted from several perspectives. Plants, fungi, and marine organisms represent sources of small molecules characterized by unique complexity related to their varied scaffolds, functional groups, and stereochemistry. At the same tim...
Sábháilte in:
| Formáid: | Online |
|---|---|
| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
|
| Ábhair: | |
| Rochtain ar líne: | ONIX_20230911_9783036584843_49 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|
| _version_ | 1869527384165711872 |
|---|---|
| collection | Directory of Open Access Books |
| description | The chemistry of natural products is rich in diversity, which can be noted from several perspectives. Plants, fungi, and marine organisms represent sources of small molecules characterized by unique complexity related to their varied scaffolds, functional groups, and stereochemistry. At the same time, extraction, de novo synthesis, derivatization, and semi-synthetic approaches represent challenging tasks for organic chemists. In parallel, analytical profiling of the content of organic compounds and microelements in natural matrices pushes experimental techniques to the edge of their potential due to the complex tasks involved in sample preparation and data elaboration. Additionally, flavonoids, alkaloids, and terpenes, as well as their semisynthetic derivatives, attract the interest of medicinal chemists due to their beneficial biological effects, which include antioxidant, antiproliferative, antibacterial, and anti-inflammatory activities. This Special Issue aimed to collect original contributions to describe the extraction, structural elucidation, and synthesis of natural, semisynthetic, and nature-inspired synthetic molecules. Moreover, articles that discuss the analysis of the content and bioactivity of natural compounds in complex matrices, as well as review articles that focus on the chemistry of natural products, were considered in combination with research articles that describe significant results in terms of their innovative synthetic and extractive, as well as advanced analytical, techniques (chromatography, 1D and 2D NMR, mass spectrometry, IR and UV spectroscopy, etc.). |
| format | Online |
| id | doab-20.500.12854ir-113916 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1139162024-03-28T03:32:56Z Natural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies Ribaudo, Giovanni vitamin D deuterium labeling liquid-chromatography tandem mass spectrometry measurement of vitamin D metabolites in blood docosahexaenoic acids ovary granulosa cells cyclophosphamide macamide larvae of Musca domestica D-IBS GI dysfunction 5-HT gut microbiota chemoenzymatic natural product synthesis biocatalysis loonamycin triple negative breast cancer p53 PI3K/AKT/mTOR O-glycan marine fungi sesquiterpenoids Aspergillus bioactivity Trapa bispinosa Roxb. TbUGGT molecular cloning expression analysis flavones chrysin kaempferol hybrids 1,2,3-triazole anticancer activity phenolics curcumin protocatechuic quinones stilbenes curcuminoids ovarian cancer natural compounds semi-synthetic compounds medicinal chemistry anti-metastasis apoptosis pyridone alkaloids Arthrinium sp. endophytic fungus antibacterial cytotoxicity n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry The chemistry of natural products is rich in diversity, which can be noted from several perspectives. Plants, fungi, and marine organisms represent sources of small molecules characterized by unique complexity related to their varied scaffolds, functional groups, and stereochemistry. At the same time, extraction, de novo synthesis, derivatization, and semi-synthetic approaches represent challenging tasks for organic chemists. In parallel, analytical profiling of the content of organic compounds and microelements in natural matrices pushes experimental techniques to the edge of their potential due to the complex tasks involved in sample preparation and data elaboration. Additionally, flavonoids, alkaloids, and terpenes, as well as their semisynthetic derivatives, attract the interest of medicinal chemists due to their beneficial biological effects, which include antioxidant, antiproliferative, antibacterial, and anti-inflammatory activities. This Special Issue aimed to collect original contributions to describe the extraction, structural elucidation, and synthesis of natural, semisynthetic, and nature-inspired synthetic molecules. Moreover, articles that discuss the analysis of the content and bioactivity of natural compounds in complex matrices, as well as review articles that focus on the chemistry of natural products, were considered in combination with research articles that describe significant results in terms of their innovative synthetic and extractive, as well as advanced analytical, techniques (chromatography, 1D and 2D NMR, mass spectrometry, IR and UV spectroscopy, etc.). 2023-09-11T12:00:06Z 2023-09-11T12:00:06Z 2023 book ONIX_20230911_9783036584843_49 9783036584843 9783036584850 https://directory.doabooks.org/handle/20.500.12854/113916 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/7759 https://mdpi.com/books/pdfview/book/7759 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8485-0 10.3390/books978-3-0365-8485-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036584843 9783036584850 228 open access |
| spellingShingle | vitamin D deuterium labeling liquid-chromatography tandem mass spectrometry measurement of vitamin D metabolites in blood docosahexaenoic acids ovary granulosa cells cyclophosphamide macamide larvae of Musca domestica D-IBS GI dysfunction 5-HT gut microbiota chemoenzymatic natural product synthesis biocatalysis loonamycin triple negative breast cancer p53 PI3K/AKT/mTOR O-glycan marine fungi sesquiterpenoids Aspergillus bioactivity Trapa bispinosa Roxb. TbUGGT molecular cloning expression analysis flavones chrysin kaempferol hybrids 1,2,3-triazole anticancer activity phenolics curcumin protocatechuic quinones stilbenes curcuminoids ovarian cancer natural compounds semi-synthetic compounds medicinal chemistry anti-metastasis apoptosis pyridone alkaloids Arthrinium sp. endophytic fungus antibacterial cytotoxicity n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry Natural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies |
| title | Natural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies |
| title_full | Natural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies |
| title_fullStr | Natural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies |
| title_full_unstemmed | Natural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies |
| title_short | Natural Products Chemistry: Advances in Synthetic, Analytical and Bioactivity Studies |
| title_sort | natural products chemistry advances in synthetic analytical and bioactivity studies |
| topic | vitamin D deuterium labeling liquid-chromatography tandem mass spectrometry measurement of vitamin D metabolites in blood docosahexaenoic acids ovary granulosa cells cyclophosphamide macamide larvae of Musca domestica D-IBS GI dysfunction 5-HT gut microbiota chemoenzymatic natural product synthesis biocatalysis loonamycin triple negative breast cancer p53 PI3K/AKT/mTOR O-glycan marine fungi sesquiterpenoids Aspergillus bioactivity Trapa bispinosa Roxb. TbUGGT molecular cloning expression analysis flavones chrysin kaempferol hybrids 1,2,3-triazole anticancer activity phenolics curcumin protocatechuic quinones stilbenes curcuminoids ovarian cancer natural compounds semi-synthetic compounds medicinal chemistry anti-metastasis apoptosis pyridone alkaloids Arthrinium sp. endophytic fungus antibacterial cytotoxicity n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry |
| topic_facet | vitamin D deuterium labeling liquid-chromatography tandem mass spectrometry measurement of vitamin D metabolites in blood docosahexaenoic acids ovary granulosa cells cyclophosphamide macamide larvae of Musca domestica D-IBS GI dysfunction 5-HT gut microbiota chemoenzymatic natural product synthesis biocatalysis loonamycin triple negative breast cancer p53 PI3K/AKT/mTOR O-glycan marine fungi sesquiterpenoids Aspergillus bioactivity Trapa bispinosa Roxb. TbUGGT molecular cloning expression analysis flavones chrysin kaempferol hybrids 1,2,3-triazole anticancer activity phenolics curcumin protocatechuic quinones stilbenes curcuminoids ovarian cancer natural compounds semi-synthetic compounds medicinal chemistry anti-metastasis apoptosis pyridone alkaloids Arthrinium sp. endophytic fungus antibacterial cytotoxicity n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry |
| url | ONIX_20230911_9783036584843_49 |