Fate of Antioxidants in Gut and Interaction of Gut Metabolites and Gut Microbiota

It is widely accepted that antioxidants can help in disease prevention by effectively quenching free radicals or inhibiting damage caused by oxidative stress. However, the final fate of antioxidants in the gut, how antioxidant metabolites affect gut microbiota, and how gut microbiota affect the meta...

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Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2023
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collection Directory of Open Access Books
description It is widely accepted that antioxidants can help in disease prevention by effectively quenching free radicals or inhibiting damage caused by oxidative stress. However, the final fate of antioxidants in the gut, how antioxidant metabolites affect gut microbiota, and how gut microbiota affect the metabolism of antioxidants are not fully understood. This Special Issue collected the latest research findings and review articles, bringing together current research and critical thinking on the fate of phytochemical antioxidants in the gut and the role antioxidant gut metabolites play in reducing oxidative stress in various gut and metabolic diseases. Both in vitro and in vivo studies relating to any of the following topics will be considered: fate of antioxidants in the gut; antioxidative activities of phytochemicals in the digestive system; molecular mechanisms of phytochemical antioxidants in maintaining gut health; and interactions of antioxidant metabolites and gut microbiota.
format Online
id doab-20.500.12854ir-113936
institution Directory of Open Access Books
language eng
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1139362024-03-28T03:30:56Z Fate of Antioxidants in Gut and Interaction of Gut Metabolites and Gut Microbiota Xu, Baojun anthocyanins berries polyphenols bioaccesibility differential pulse voltammetry first-pass metabolism HPLC-ESI-QTOF-MS apparent permeability oxidative stress inflammation antioxidant anthocyanin phenolic acid antioxidant capacity medium chain fatty acids short chain fatty acids gut microbiome Ougan (Citrus reticulata cv. Suavissima) polymethoxyflavones gut microbiota metabolism in vivo metabolite identification beneficial regulatory effect Dendropanax morbifera hepatoprotective leaf extract liver damage alcoholism oxidative damage dietary polyphenols metabolites epigenetics microflora cardiometabolic complications selenium zinc bioaccumulation antioxidant capacities intestinal microbiota inhibition metabolism catabolism biotransformation bioactive compounds health diversity dysbiosis leaky gut endotoxemia fatty liver disease ethanol phytochemicals quercetin high-fat diet insulin resistance Bacillus amyloliquefaciens SC06 IPEC-J2 autophagy apoptosis AKT–FOXO thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society It is widely accepted that antioxidants can help in disease prevention by effectively quenching free radicals or inhibiting damage caused by oxidative stress. However, the final fate of antioxidants in the gut, how antioxidant metabolites affect gut microbiota, and how gut microbiota affect the metabolism of antioxidants are not fully understood. This Special Issue collected the latest research findings and review articles, bringing together current research and critical thinking on the fate of phytochemical antioxidants in the gut and the role antioxidant gut metabolites play in reducing oxidative stress in various gut and metabolic diseases. Both in vitro and in vivo studies relating to any of the following topics will be considered: fate of antioxidants in the gut; antioxidative activities of phytochemicals in the digestive system; molecular mechanisms of phytochemical antioxidants in maintaining gut health; and interactions of antioxidant metabolites and gut microbiota. 2023-09-11T12:05:19Z 2023-09-11T12:05:19Z 2023 book ONIX_20230911_9783036585321_69 9783036585321 9783036585338 https://directory.doabooks.org/handle/20.500.12854/113936 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/7779 https://mdpi.com/books/pdfview/book/7779 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8533-8 10.3390/books978-3-0365-8533-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036585321 9783036585338 312 open access
spellingShingle anthocyanins
berries
polyphenols
bioaccesibility
differential pulse voltammetry
first-pass metabolism
HPLC-ESI-QTOF-MS
apparent permeability
oxidative stress
inflammation
antioxidant
anthocyanin
phenolic acid
antioxidant capacity
medium chain fatty acids
short chain fatty acids
gut microbiome
Ougan (Citrus reticulata cv. Suavissima)
polymethoxyflavones
gut microbiota
metabolism in vivo
metabolite identification
beneficial regulatory effect
Dendropanax morbifera
hepatoprotective
leaf extract
liver damage
alcoholism
oxidative damage
dietary polyphenols
metabolites
epigenetics
microflora
cardiometabolic complications
selenium
zinc
bioaccumulation
antioxidant capacities
intestinal microbiota
inhibition
metabolism
catabolism
biotransformation
bioactive compounds
health
diversity
dysbiosis
leaky gut
endotoxemia
fatty liver disease
ethanol
phytochemicals
quercetin
high-fat diet
insulin resistance
Bacillus amyloliquefaciens SC06
IPEC-J2
autophagy
apoptosis
AKT–FOXO
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
Fate of Antioxidants in Gut and Interaction of Gut Metabolites and Gut Microbiota
title Fate of Antioxidants in Gut and Interaction of Gut Metabolites and Gut Microbiota
title_full Fate of Antioxidants in Gut and Interaction of Gut Metabolites and Gut Microbiota
title_fullStr Fate of Antioxidants in Gut and Interaction of Gut Metabolites and Gut Microbiota
title_full_unstemmed Fate of Antioxidants in Gut and Interaction of Gut Metabolites and Gut Microbiota
title_short Fate of Antioxidants in Gut and Interaction of Gut Metabolites and Gut Microbiota
title_sort fate of antioxidants in gut and interaction of gut metabolites and gut microbiota
topic anthocyanins
berries
polyphenols
bioaccesibility
differential pulse voltammetry
first-pass metabolism
HPLC-ESI-QTOF-MS
apparent permeability
oxidative stress
inflammation
antioxidant
anthocyanin
phenolic acid
antioxidant capacity
medium chain fatty acids
short chain fatty acids
gut microbiome
Ougan (Citrus reticulata cv. Suavissima)
polymethoxyflavones
gut microbiota
metabolism in vivo
metabolite identification
beneficial regulatory effect
Dendropanax morbifera
hepatoprotective
leaf extract
liver damage
alcoholism
oxidative damage
dietary polyphenols
metabolites
epigenetics
microflora
cardiometabolic complications
selenium
zinc
bioaccumulation
antioxidant capacities
intestinal microbiota
inhibition
metabolism
catabolism
biotransformation
bioactive compounds
health
diversity
dysbiosis
leaky gut
endotoxemia
fatty liver disease
ethanol
phytochemicals
quercetin
high-fat diet
insulin resistance
Bacillus amyloliquefaciens SC06
IPEC-J2
autophagy
apoptosis
AKT–FOXO
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
topic_facet anthocyanins
berries
polyphenols
bioaccesibility
differential pulse voltammetry
first-pass metabolism
HPLC-ESI-QTOF-MS
apparent permeability
oxidative stress
inflammation
antioxidant
anthocyanin
phenolic acid
antioxidant capacity
medium chain fatty acids
short chain fatty acids
gut microbiome
Ougan (Citrus reticulata cv. Suavissima)
polymethoxyflavones
gut microbiota
metabolism in vivo
metabolite identification
beneficial regulatory effect
Dendropanax morbifera
hepatoprotective
leaf extract
liver damage
alcoholism
oxidative damage
dietary polyphenols
metabolites
epigenetics
microflora
cardiometabolic complications
selenium
zinc
bioaccumulation
antioxidant capacities
intestinal microbiota
inhibition
metabolism
catabolism
biotransformation
bioactive compounds
health
diversity
dysbiosis
leaky gut
endotoxemia
fatty liver disease
ethanol
phytochemicals
quercetin
high-fat diet
insulin resistance
Bacillus amyloliquefaciens SC06
IPEC-J2
autophagy
apoptosis
AKT–FOXO
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
url ONIX_20230911_9783036585321_69