Novel Strategies for Biodegradation and Detoxification of Mycotoxins

Mycotoxins contamination is a continuing global problem that severely affects animal health and performance, and further threatens food safety. The industry's common aspiration is to eliminate feed mycotoxins contamination and control their hazards. In recent years, animal mycotoxicosis has occurred...

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Format: Online
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Wydane: MDPI - Multidisciplinary Digital Publishing Institute 2023
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description Mycotoxins contamination is a continuing global problem that severely affects animal health and performance, and further threatens food safety. The industry's common aspiration is to eliminate feed mycotoxins contamination and control their hazards. In recent years, animal mycotoxicosis has occurred frequently all over the world, which has brought huge economic losses to the agriculture industry. The potential damage caused by mycotoxins-induced decreased disease resistance in animals and food safety problems in human health is incalculable. There is a long way to go to prevent mycotoxins hazards. Biodegradation is a promising strategy to eliminate mycotoxins as it can transform mycotoxins into nontoxic or less toxic metabolites under mild conditions, retaining the sensory quality and nutritional value of agricultural commodities. Moreover, animals have a certain ability to detoxify mycotoxins, and some bioactive substances, such as lipoic acid, sporoderm-broken spores of Ganoderma lucidum, and quercetin, can improve the detoxification ability of animals to reduce the toxic effects of mycotoxins. This reprint aimed to gather contributions of original research or reviews related to novel strategies for biodegradation and detoxification of mycotoxins. Topics of interest will include novel mycotoxin-degrading microorganisms and enzymes, fermentation technology to reduce the mycotoxin content in cereal products, studies on alleviating the mycotoxicosis of livestock by the addition of bioactive substances or mycotoxin biodegradation agents, and any preliminary research that promotes progress in this field.
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spelling doab-20.500.12854ir-1139602024-04-11T15:11:13Z Novel Strategies for Biodegradation and Detoxification of Mycotoxins Ma, Qiugang Qi, Desheng Zhao, Lihong zearalenone degradable Bacillus subtilis probiotic Bacillus subtilis gilts glutamine PI3K/Akt pathway apoptosis IPEC-J2 cells thymol Fusarium graminearum deoxynivalenol mycelial growth toxin production gluconeogenesis/glycolysis aflatoxin Bacillus amyloliquefaciens laccase degradation molecular docking mutagenesis aflatoxin B1 porcine porcine alveolar macrophages cell cycle patulin mycotoxin manganese peroxidase apple juice detoxification Aspergillus flavus conidia germination transcriptome redox genes ochratoxin A biodegradation Alcaligenes faecalis ANSA176 immune injury inflammation layers cinnamaldehyde citral inhibition synergy antioxidant property catalase gut microbiota intestinal health duckling epigallocatechin gallate glutathione oxidative stress Keap1/Nrf2 signalling Cicer arietinum L. mycotoxigenic fungi mycotoxin occurrence pest attack nitrogen-controlled atmosphere ozone corn bioremediation degradation products hydrogen peroxide ascorbic acid dehydroascorbic acid AFQ1 AFB2a AFB1-diol DON biodegradation 3-keto-DON toxicity Ketogulonicigenium vulgare PQQ-dependent alcohol dehydrogenases n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology Mycotoxins contamination is a continuing global problem that severely affects animal health and performance, and further threatens food safety. The industry's common aspiration is to eliminate feed mycotoxins contamination and control their hazards. In recent years, animal mycotoxicosis has occurred frequently all over the world, which has brought huge economic losses to the agriculture industry. The potential damage caused by mycotoxins-induced decreased disease resistance in animals and food safety problems in human health is incalculable. There is a long way to go to prevent mycotoxins hazards. Biodegradation is a promising strategy to eliminate mycotoxins as it can transform mycotoxins into nontoxic or less toxic metabolites under mild conditions, retaining the sensory quality and nutritional value of agricultural commodities. Moreover, animals have a certain ability to detoxify mycotoxins, and some bioactive substances, such as lipoic acid, sporoderm-broken spores of Ganoderma lucidum, and quercetin, can improve the detoxification ability of animals to reduce the toxic effects of mycotoxins. This reprint aimed to gather contributions of original research or reviews related to novel strategies for biodegradation and detoxification of mycotoxins. Topics of interest will include novel mycotoxin-degrading microorganisms and enzymes, fermentation technology to reduce the mycotoxin content in cereal products, studies on alleviating the mycotoxicosis of livestock by the addition of bioactive substances or mycotoxin biodegradation agents, and any preliminary research that promotes progress in this field. 2023-09-11T12:11:47Z 2023-09-11T12:11:47Z 2023 book ONIX_20230911_9783036584140_93 9783036584140 9783036584157 https://directory.doabooks.org/handle/20.500.12854/113960 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/7804 https://mdpi.com/books/pdfview/book/7804 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8415-7 10.3390/books978-3-0365-8415-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036584140 9783036584157 234 open access
spellingShingle zearalenone
degradable Bacillus subtilis
probiotic Bacillus subtilis
gilts
glutamine
PI3K/Akt pathway
apoptosis
IPEC-J2 cells
thymol
Fusarium graminearum
deoxynivalenol
mycelial growth
toxin production
gluconeogenesis/glycolysis
aflatoxin
Bacillus amyloliquefaciens
laccase
degradation
molecular docking
mutagenesis
aflatoxin B1
porcine
porcine alveolar macrophages
cell cycle
patulin
mycotoxin
manganese peroxidase
apple juice
detoxification
Aspergillus flavus
conidia
germination
transcriptome
redox genes
ochratoxin A
biodegradation
Alcaligenes faecalis ANSA176
immune injury
inflammation
layers
cinnamaldehyde
citral
inhibition
synergy
antioxidant property
catalase
gut microbiota
intestinal health
duckling
epigallocatechin gallate
glutathione
oxidative stress
Keap1/Nrf2 signalling
Cicer arietinum L.
mycotoxigenic fungi
mycotoxin occurrence
pest attack
nitrogen-controlled atmosphere
ozone
corn
bioremediation
degradation products
hydrogen peroxide
ascorbic acid
dehydroascorbic acid
AFQ1
AFB2a
AFB1-diol
DON biodegradation
3-keto-DON
toxicity
Ketogulonicigenium vulgare
PQQ-dependent alcohol dehydrogenases
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
Novel Strategies for Biodegradation and Detoxification of Mycotoxins
title Novel Strategies for Biodegradation and Detoxification of Mycotoxins
title_full Novel Strategies for Biodegradation and Detoxification of Mycotoxins
title_fullStr Novel Strategies for Biodegradation and Detoxification of Mycotoxins
title_full_unstemmed Novel Strategies for Biodegradation and Detoxification of Mycotoxins
title_short Novel Strategies for Biodegradation and Detoxification of Mycotoxins
title_sort novel strategies for biodegradation and detoxification of mycotoxins
topic zearalenone
degradable Bacillus subtilis
probiotic Bacillus subtilis
gilts
glutamine
PI3K/Akt pathway
apoptosis
IPEC-J2 cells
thymol
Fusarium graminearum
deoxynivalenol
mycelial growth
toxin production
gluconeogenesis/glycolysis
aflatoxin
Bacillus amyloliquefaciens
laccase
degradation
molecular docking
mutagenesis
aflatoxin B1
porcine
porcine alveolar macrophages
cell cycle
patulin
mycotoxin
manganese peroxidase
apple juice
detoxification
Aspergillus flavus
conidia
germination
transcriptome
redox genes
ochratoxin A
biodegradation
Alcaligenes faecalis ANSA176
immune injury
inflammation
layers
cinnamaldehyde
citral
inhibition
synergy
antioxidant property
catalase
gut microbiota
intestinal health
duckling
epigallocatechin gallate
glutathione
oxidative stress
Keap1/Nrf2 signalling
Cicer arietinum L.
mycotoxigenic fungi
mycotoxin occurrence
pest attack
nitrogen-controlled atmosphere
ozone
corn
bioremediation
degradation products
hydrogen peroxide
ascorbic acid
dehydroascorbic acid
AFQ1
AFB2a
AFB1-diol
DON biodegradation
3-keto-DON
toxicity
Ketogulonicigenium vulgare
PQQ-dependent alcohol dehydrogenases
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
topic_facet zearalenone
degradable Bacillus subtilis
probiotic Bacillus subtilis
gilts
glutamine
PI3K/Akt pathway
apoptosis
IPEC-J2 cells
thymol
Fusarium graminearum
deoxynivalenol
mycelial growth
toxin production
gluconeogenesis/glycolysis
aflatoxin
Bacillus amyloliquefaciens
laccase
degradation
molecular docking
mutagenesis
aflatoxin B1
porcine
porcine alveolar macrophages
cell cycle
patulin
mycotoxin
manganese peroxidase
apple juice
detoxification
Aspergillus flavus
conidia
germination
transcriptome
redox genes
ochratoxin A
biodegradation
Alcaligenes faecalis ANSA176
immune injury
inflammation
layers
cinnamaldehyde
citral
inhibition
synergy
antioxidant property
catalase
gut microbiota
intestinal health
duckling
epigallocatechin gallate
glutathione
oxidative stress
Keap1/Nrf2 signalling
Cicer arietinum L.
mycotoxigenic fungi
mycotoxin occurrence
pest attack
nitrogen-controlled atmosphere
ozone
corn
bioremediation
degradation products
hydrogen peroxide
ascorbic acid
dehydroascorbic acid
AFQ1
AFB2a
AFB1-diol
DON biodegradation
3-keto-DON
toxicity
Ketogulonicigenium vulgare
PQQ-dependent alcohol dehydrogenases
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
url ONIX_20230911_9783036584140_93