Clinical Relevance of Brain Atrophy Measures in Multiple Sclerosis

Magnetic resonance imaging of the brain and spinal cord in patients with multiple sclerosis is crucial for diagnosis as well as monitoring and predicting disease activity. Comprehensive MR measurements including assessment of brain and spinal cord volume changes have the potential to improve patient...

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Príomhchruthaitheoir: Uher, Tomáš
Formáid: Online
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Foilsithe / Cruthaithe: Karolinum Press 2023
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Rochtain ar líne:https://directory.doabooks.org/handle/20.500.12854/121168
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author Uher, Tomáš
author_browse Uher, Tomáš
author_facet Uher, Tomáš
author_sort Uher, Tomáš
collection Directory of Open Access Books
description Magnetic resonance imaging of the brain and spinal cord in patients with multiple sclerosis is crucial for diagnosis as well as monitoring and predicting disease activity. Comprehensive MR measurements including assessment of brain and spinal cord volume changes have the potential to improve patient monitoring, allow earlier detection of subclinical disease activity, and identify patients with depleted brain reserve who are at highest risk of disability progression. Cerebral atrophy measurements are now a secondary outcome of many clinical trials, although their wider use in routine clinical practice is still hampered by some technical limitations. However, evidence from clinical practice shows that assessment of brain and spinal cord volume change is feasible and has the potential to improve patient treatment.
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spelling doab-20.500.12854ir-1211682024-03-30T23:22:05Z Clinical Relevance of Brain Atrophy Measures in Multiple Sclerosis Uher, Tomáš multiple sclerosis brain atrophy diagnosis measurements disease monitoring magnetic resonance cerebral atrophy thema EDItEUR::M Medicine and Nursing Magnetic resonance imaging of the brain and spinal cord in patients with multiple sclerosis is crucial for diagnosis as well as monitoring and predicting disease activity. Comprehensive MR measurements including assessment of brain and spinal cord volume changes have the potential to improve patient monitoring, allow earlier detection of subclinical disease activity, and identify patients with depleted brain reserve who are at highest risk of disability progression. Cerebral atrophy measurements are now a secondary outcome of many clinical trials, although their wider use in routine clinical practice is still hampered by some technical limitations. However, evidence from clinical practice shows that assessment of brain and spinal cord volume change is feasible and has the potential to improve patient treatment. Published 2023-10-31T07:42:29Z 2023-10-31T07:42:29Z 2023-10 book 9788024651965 9788024656922 https://directory.doabooks.org/handle/20.500.12854/121168 eng image/jpeg Attribution 4.0 International https://karolinum.cz/knihy/uher-clinical-relevance-of-brain-atrophy-measures-in-multiple-sclerosis-28939 https://dspace.cuni.cz/bitstream/handle/20.500.11956/186866/9788024651965.pdf Karolinum Press 10.14712/9788024651965 10.14712/9788024651965 8d94c6aa-2a71-4559-9698-bf3e883a574a b77fb797-b1d1-44fb-a755-1b44fe24463c 9788024651965 9788024656922 83 Prague NU22-04-00193 European Commission European Union 10.13039/501100000780 open access
spellingShingle multiple sclerosis
brain atrophy
diagnosis
measurements
disease
monitoring
magnetic resonance
cerebral atrophy
thema EDItEUR::M Medicine and Nursing
Uher, Tomáš
Clinical Relevance of Brain Atrophy Measures in Multiple Sclerosis
title Clinical Relevance of Brain Atrophy Measures in Multiple Sclerosis
title_full Clinical Relevance of Brain Atrophy Measures in Multiple Sclerosis
title_fullStr Clinical Relevance of Brain Atrophy Measures in Multiple Sclerosis
title_full_unstemmed Clinical Relevance of Brain Atrophy Measures in Multiple Sclerosis
title_short Clinical Relevance of Brain Atrophy Measures in Multiple Sclerosis
title_sort clinical relevance of brain atrophy measures in multiple sclerosis
topic multiple sclerosis
brain atrophy
diagnosis
measurements
disease
monitoring
magnetic resonance
cerebral atrophy
thema EDItEUR::M Medicine and Nursing
topic_facet multiple sclerosis
brain atrophy
diagnosis
measurements
disease
monitoring
magnetic resonance
cerebral atrophy
thema EDItEUR::M Medicine and Nursing
url https://directory.doabooks.org/handle/20.500.12854/121168
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