Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications
Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications covers current knowledge about stem cell delivery for cell-based therapeutics. Starting with an introduction to stem cell technology, the book provides information about the main mesenchymal stem cell (MSC) delivery routes a...
Sábháilte in:
| Príomhchruthaitheoir: | |
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| Formáid: | Online |
| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
Bentham Science Publishers
2023
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| Ábhair: | |
| Rochtain ar líne: | ONIX_20230828_9789815040104_13 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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| _version_ | 1869524891301052416 |
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| author | Fagoonee, Sharmila |
| author_browse | Fagoonee, Sharmila |
| author_facet | Fagoonee, Sharmila |
| author_sort | Fagoonee, Sharmila |
| collection | Directory of Open Access Books |
| description | Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications covers current knowledge about stem cell delivery for cell-based therapeutics. Starting with an introduction to stem cell technology, the book provides information about the main mesenchymal stem cell (MSC) delivery routes and the cell carrier materials used for delivering the cells. The main delivery routes include the liver, the kidney and the ocular surface. This introductory information is followed up with general information about stem cell based therapeutics, covering relevant topics such as the secretome and optimal delivery strategies in cell-based therapeutics. The book then progresses into the topic of in vivo cell tracking methods in preclinical and clinical studies with specific emphasis on the liver, ocular surface and kidney while also covering factors that affect the residence time, viability, and homing of MSCs with respect to the targeted location. The discussions in these chapters are accompanied by key descriptions of MSC-based therapeutic applications in rodent models and human clinical studies. The advantages and bottlenecks in clinical MSC application, and ways to improve the therapeutic efficacy of transplanted cells are also presented, rounding up the contents of the book. Key Feature: - A comprehensive summary of stem cell delivery for cell-based therapeutics, suitable for a broad range of readers - 10 sequential chapters that enhance the reader’s understanding on the subject - An Introduction to stem cell technology - Coverage of 3 key stem cell transplantation routes (liver, kidney and eye) - Coverage of in vivo stem cell tracking - Inclusion of basic information about MSC delivery and methods of clinical applications - Discussions about preclinical mouse models - A perspective on stem cell bottlenecks and recent advances in biomedical engineering that enhance the clinical application of MSCs The contents are adapted to suit readers learning about advanced stem cells therapies at all academic levels, including undergraduates, lecturers, as well as those who are curious to understand more about the importance of stem cells, and their application in cell-based therapeutics. Professionals involved in allied fields in clinical research, and biomedical engineering will also gain a substantial understanding about regenerative medicine and cell transplantation. |
| format | Online |
| id | doab-20.500.12854ir-121656 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Bentham Science Publishers |
| publisherStr | Bentham Science Publishers |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1216562025-03-20T17:52:28Z Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications Fagoonee, Sharmila Stem Cell Bioengineering Stem Cell Technology Extracellular vesicles Mouse stem cell models Stem Cell transplantation Cell transplantation Medical Biotechnology Secretome Cell-based therapeutics stem cell tracking Genetic engineering tissue engineering Cell-free therapy biomaterials Transplantation routes cell delivery liver stem cells cornea transplant kidney transplants regenerative medicine Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications covers current knowledge about stem cell delivery for cell-based therapeutics. Starting with an introduction to stem cell technology, the book provides information about the main mesenchymal stem cell (MSC) delivery routes and the cell carrier materials used for delivering the cells. The main delivery routes include the liver, the kidney and the ocular surface. This introductory information is followed up with general information about stem cell based therapeutics, covering relevant topics such as the secretome and optimal delivery strategies in cell-based therapeutics. The book then progresses into the topic of in vivo cell tracking methods in preclinical and clinical studies with specific emphasis on the liver, ocular surface and kidney while also covering factors that affect the residence time, viability, and homing of MSCs with respect to the targeted location. The discussions in these chapters are accompanied by key descriptions of MSC-based therapeutic applications in rodent models and human clinical studies. The advantages and bottlenecks in clinical MSC application, and ways to improve the therapeutic efficacy of transplanted cells are also presented, rounding up the contents of the book. Key Feature: - A comprehensive summary of stem cell delivery for cell-based therapeutics, suitable for a broad range of readers - 10 sequential chapters that enhance the reader’s understanding on the subject - An Introduction to stem cell technology - Coverage of 3 key stem cell transplantation routes (liver, kidney and eye) - Coverage of in vivo stem cell tracking - Inclusion of basic information about MSC delivery and methods of clinical applications - Discussions about preclinical mouse models - A perspective on stem cell bottlenecks and recent advances in biomedical engineering that enhance the clinical application of MSCs The contents are adapted to suit readers learning about advanced stem cells therapies at all academic levels, including undergraduates, lecturers, as well as those who are curious to understand more about the importance of stem cells, and their application in cell-based therapeutics. Professionals involved in allied fields in clinical research, and biomedical engineering will also gain a substantial understanding about regenerative medicine and cell transplantation. 2023-11-17T08:23:13Z 2023-11-17T08:23:13Z 2023-08-28T16:21:20Z 2021 book ONIX_20230828_9789815040104_13 OCN: 1365391091 https://library.oapen.org/handle/20.500.12657/75870 9789815040104 9789815040111 https://directory.doabooks.org/handle/20.500.12854/121656 eng open access image/jpeg image/jpeg Attribution 4.0 International Attribution 4.0 International https://library.oapen.org/bitstream/20.500.12657/75870/1/9789815040104.pdf https://library.oapen.org/bitstream/20.500.12657/75870/1/9789815040104.pdf Bentham Science Publishers Bentham Science Publishers 10.2174/97898150401041210101 10.2174/97898150401041210101 c74825a7-62e6-42db-a8db-21c5934eab49 9789815040104 9789815040111 Bentham Science Publishers 160 open access |
| spellingShingle | Stem Cell Bioengineering Stem Cell Technology Extracellular vesicles Mouse stem cell models Stem Cell transplantation Cell transplantation Medical Biotechnology Secretome Cell-based therapeutics stem cell tracking Genetic engineering tissue engineering Cell-free therapy biomaterials Transplantation routes cell delivery liver stem cells cornea transplant kidney transplants regenerative medicine Fagoonee, Sharmila Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications |
| title | Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications |
| title_full | Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications |
| title_fullStr | Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications |
| title_full_unstemmed | Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications |
| title_short | Stem Cell Delivery Routes: From Preclinical Models to Clinical Applications |
| title_sort | stem cell delivery routes from preclinical models to clinical applications |
| topic | Stem Cell Bioengineering Stem Cell Technology Extracellular vesicles Mouse stem cell models Stem Cell transplantation Cell transplantation Medical Biotechnology Secretome Cell-based therapeutics stem cell tracking Genetic engineering tissue engineering Cell-free therapy biomaterials Transplantation routes cell delivery liver stem cells cornea transplant kidney transplants regenerative medicine |
| topic_facet | Stem Cell Bioengineering Stem Cell Technology Extracellular vesicles Mouse stem cell models Stem Cell transplantation Cell transplantation Medical Biotechnology Secretome Cell-based therapeutics stem cell tracking Genetic engineering tissue engineering Cell-free therapy biomaterials Transplantation routes cell delivery liver stem cells cornea transplant kidney transplants regenerative medicine |
| url | ONIX_20230828_9789815040104_13 |
| work_keys_str_mv | AT fagooneesharmila stemcelldeliveryroutesfrompreclinicalmodelstoclinicalapplications |