Cellular Mechanisms of Cardiovascular Disease

Cardiovascular diseases (CVD) remain the major cause of mortality and disability worldwide. Although cardiovascular outcomes have significantly improved due to early diagnosis and timely treatment, the prevalence of CVD is expected to increase in the coming years, highlighting the pressing need to i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
स्वरूप: Online
भाषा:अंग्रेज़ी
प्रकाशित: MDPI - Multidisciplinary Digital Publishing Institute 2023
विषय:
ऑनलाइन पहुंच:ONIX_20231130_9783036589886_27
टैग: टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
_version_ 1869517264052551680
collection Directory of Open Access Books
description Cardiovascular diseases (CVD) remain the major cause of mortality and disability worldwide. Although cardiovascular outcomes have significantly improved due to early diagnosis and timely treatment, the prevalence of CVD is expected to increase in the coming years, highlighting the pressing need to identify novel biomarkers and disease-modifying treatments. In addition to classical risk factors, CVD burden is now recognized to be aggravated due to the growing population of cancer survivors treated with cardiotoxic cancer therapies or radiotherapy, which has fostered the development of a new field of research—cardio-oncology. Across the spectrum of CVD, multiple molecular pathways converge in endothelial dysfunction and myocardial remodeling, including inflammation, oxidative stress, defective calcium homeostasis, intercellular communication, and metabolic abnormalities. Therefore, a major future challenge in cardiovascular medicine lies in understanding the molecular basis of cardiac and valvular remodeling, paving the way for the identification of more efficient diagnostic and therapeutic tools. This Special Issue intended to bring together the latest findings in the field of cardiovascular biology and cardio-oncology, involving both cell-based studies and animal models of CVD, aiming to identify novel mechanisms underlying cardiac remodeling and dysfunction.
format Online
id doab-20.500.12854ir-128575
institution Directory of Open Access Books
language eng
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1285752024-03-28T03:33:16Z Cellular Mechanisms of Cardiovascular Disease Martins-Marques, Tânia Coutinho, Gonçalo F. Kiss, Attila cardiovascular biology myocardial infarction cardiac remodeling atherosclerosis heart failure thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Cardiovascular diseases (CVD) remain the major cause of mortality and disability worldwide. Although cardiovascular outcomes have significantly improved due to early diagnosis and timely treatment, the prevalence of CVD is expected to increase in the coming years, highlighting the pressing need to identify novel biomarkers and disease-modifying treatments. In addition to classical risk factors, CVD burden is now recognized to be aggravated due to the growing population of cancer survivors treated with cardiotoxic cancer therapies or radiotherapy, which has fostered the development of a new field of research—cardio-oncology. Across the spectrum of CVD, multiple molecular pathways converge in endothelial dysfunction and myocardial remodeling, including inflammation, oxidative stress, defective calcium homeostasis, intercellular communication, and metabolic abnormalities. Therefore, a major future challenge in cardiovascular medicine lies in understanding the molecular basis of cardiac and valvular remodeling, paving the way for the identification of more efficient diagnostic and therapeutic tools. This Special Issue intended to bring together the latest findings in the field of cardiovascular biology and cardio-oncology, involving both cell-based studies and animal models of CVD, aiming to identify novel mechanisms underlying cardiac remodeling and dysfunction. 2023-11-30T20:32:56Z 2023-11-30T20:32:56Z 2023 book ONIX_20231130_9783036589886_27 9783036589886 9783036589893 https://directory.doabooks.org/handle/20.500.12854/128575 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/8027 https://mdpi.com/books/pdfview/book/8027 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-8989-3 10.3390/books978-3-0365-8989-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036589886 9783036589893 294 Basel open access
spellingShingle cardiovascular biology
myocardial infarction
cardiac remodeling
atherosclerosis
heart failure
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Cellular Mechanisms of Cardiovascular Disease
title Cellular Mechanisms of Cardiovascular Disease
title_full Cellular Mechanisms of Cardiovascular Disease
title_fullStr Cellular Mechanisms of Cardiovascular Disease
title_full_unstemmed Cellular Mechanisms of Cardiovascular Disease
title_short Cellular Mechanisms of Cardiovascular Disease
title_sort cellular mechanisms of cardiovascular disease
topic cardiovascular biology
myocardial infarction
cardiac remodeling
atherosclerosis
heart failure
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet cardiovascular biology
myocardial infarction
cardiac remodeling
atherosclerosis
heart failure
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20231130_9783036589886_27