Reactive Sulfur Species in Biology and Medicine
Hydrogen sulfide (H2S) is a naturally occurring signaling molecule produced in vivo and plays a pivotal role in regulating a wide array of physiological processes. Additionally, emerging findings have illuminated that many of the biological effects initially attributed to H2S may actually stem from...
Sparad:
| Materialtyp: | Online |
|---|---|
| Språk: | engelska |
| Utgiven: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
|
| Ämnen: | |
| Länkar: | ONIX_20231130_9783036591209_85 |
| Taggar: |
Inga taggar, Lägg till första taggen!
|
| _version_ | 1869520063815483392 |
|---|---|
| collection | Directory of Open Access Books |
| description | Hydrogen sulfide (H2S) is a naturally occurring signaling molecule produced in vivo and plays a pivotal role in regulating a wide array of physiological processes. Additionally, emerging findings have illuminated that many of the biological effects initially attributed to H2S may actually stem from other reactive sulfur species (RSS), including hydropersulfides (RSSH) and various higher-order polysulfur species (RSSnH, RSSnR, and HSnH, where n > 1). These studies have underscored the contributions of these species to essential cellular processes, such as the efficient scavenging of reactive oxygen species and electrophiles, and their influence on mitochondrial function. Nonetheless, the chemistry of RSS remains challenging due to their inherently reactive nature, and their precise measurement within biological systems continues to pose a formidable challenge. This compilation of reprints focuses on recent advancements in the field of H2S/RSS chemical biology. It encompasses original research studies and comprehensive reviews, all geared towards exploring the therapeutic potential of H2S/RSS donors in the treatment of various conditions, including cancer, neurological disorders, and cardiovascular disease. Furthermore, it delves into the molecular mechanisms and physiological roles played by RSS along with the development of methodologies for quantifying and measuring the distribution of RSS within biological systems. |
| format | Online |
| id | doab-20.500.12854ir-128633 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1286332024-03-28T03:31:11Z Reactive Sulfur Species in Biology and Medicine Toscano, John Khodade, Vinayak reactive sulfur species hydrogen sulfide polysulfides pharmacology thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Hydrogen sulfide (H2S) is a naturally occurring signaling molecule produced in vivo and plays a pivotal role in regulating a wide array of physiological processes. Additionally, emerging findings have illuminated that many of the biological effects initially attributed to H2S may actually stem from other reactive sulfur species (RSS), including hydropersulfides (RSSH) and various higher-order polysulfur species (RSSnH, RSSnR, and HSnH, where n > 1). These studies have underscored the contributions of these species to essential cellular processes, such as the efficient scavenging of reactive oxygen species and electrophiles, and their influence on mitochondrial function. Nonetheless, the chemistry of RSS remains challenging due to their inherently reactive nature, and their precise measurement within biological systems continues to pose a formidable challenge. This compilation of reprints focuses on recent advancements in the field of H2S/RSS chemical biology. It encompasses original research studies and comprehensive reviews, all geared towards exploring the therapeutic potential of H2S/RSS donors in the treatment of various conditions, including cancer, neurological disorders, and cardiovascular disease. Furthermore, it delves into the molecular mechanisms and physiological roles played by RSS along with the development of methodologies for quantifying and measuring the distribution of RSS within biological systems. 2023-11-30T20:38:18Z 2023-11-30T20:38:18Z 2023 book ONIX_20231130_9783036591209_85 9783036591209 9783036591216 https://directory.doabooks.org/handle/20.500.12854/128633 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/8085 https://mdpi.com/books/pdfview/book/8085 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9121-6 10.3390/books978-3-0365-9121-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036591209 9783036591216 210 Basel open access |
| spellingShingle | reactive sulfur species hydrogen sulfide polysulfides pharmacology thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Reactive Sulfur Species in Biology and Medicine |
| title | Reactive Sulfur Species in Biology and Medicine |
| title_full | Reactive Sulfur Species in Biology and Medicine |
| title_fullStr | Reactive Sulfur Species in Biology and Medicine |
| title_full_unstemmed | Reactive Sulfur Species in Biology and Medicine |
| title_short | Reactive Sulfur Species in Biology and Medicine |
| title_sort | reactive sulfur species in biology and medicine |
| topic | reactive sulfur species hydrogen sulfide polysulfides pharmacology thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | reactive sulfur species hydrogen sulfide polysulfides pharmacology thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20231130_9783036591209_85 |