Porphyrin-Based Compounds: Synthesis and Application

Porphyrins, metalloporphyrins, and their analogs are a family of macrocycles that are ubiquitous in nature, playing key roles in a myriad of biological functions, such as in plant light-harvesting (e.g., chlorophyll, a magnesium–chlorin complex), oxygen binding and transport (e.g., heme group, an ir...

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collection Directory of Open Access Books
description Porphyrins, metalloporphyrins, and their analogs are a family of macrocycles that are ubiquitous in nature, playing key roles in a myriad of biological functions, such as in plant light-harvesting (e.g., chlorophyll, a magnesium–chlorin complex), oxygen binding and transport (e.g., heme group, an iron–porphyrin complex, responsible for animal cellular respiration), and bacteria photosynthesis. The pivotal functions fulfilled by these naturally occurring porphyrinoids have motivated and inspired organic chemists to produce synthetic porphyrins and analogs in the laboratory. In recent years, a multitude of applications for porphyrins has shifted the focus from purely academic interest to industrial processes. There is a growing recognition of the need to develop new, more selective, and environmentally friendly synthetic methods. Within this Special Issue, readers will find a collection of 16 original research papers and a comprehensive review, all dedicated to exploring the synthesis and functionalization of tetrapyrrolic macrocycles. These papers shed light on the vast potential applications of these compounds across various fields.
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publishDate 2023
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-1288202024-03-28T03:33:05Z Porphyrin-Based Compounds: Synthesis and Application Monteiro, Carlos J. P. Faustino, M. Amparo F. Serpa, Carlos porphyrin human serum albumin spectroscopy molecular docking chemical-biological interactions Spirulina maxima chlorophyll a derivatives photosensitizers semisynthesis photodynamic inactivation array artificial photosynthesis building block copper-free Sonogashira coupling ethyne perylene solar carboxylated pyrrolidine-fused chlorin fluorescence glutathione detection porphyrin macrocycles photodynamic therapy theranostic agents corroles trans-A2B-corroles photophysics photobiology asymmetrical porphyrins human U937 monocytic cells transmembrane potential membrane anisotropy sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2b) Slo1 SUR2 asymmetric catalysis Diels–Alder reaction imidazolidin-4-ones organocatalysis photocatalysis porphyrins reductive amination sulfonamides MRSA antimicrobial resistance photosensitizer singlet oxygen potassium iodide gram-positive bacteria Staphylococcus aureus copper-64 positron emission tomography circular dichroism chirality chiral layers supramolecular chirality reflectance anisotropy spectroscopy DFT organometallic density functionals transition metals green chemistry C-H functionalization epoxidation iron porphyrin oxidation catalysis renewable aromatics phthalocyanines solubility gas sensors quartz microbalances porphyrinoids phenothiazine radical cation EPR spectroscopy ENDOR HYSCORE spectroelectrochemistry BODIPY pyridyl nitro chloro methyl ester n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry Porphyrins, metalloporphyrins, and their analogs are a family of macrocycles that are ubiquitous in nature, playing key roles in a myriad of biological functions, such as in plant light-harvesting (e.g., chlorophyll, a magnesium–chlorin complex), oxygen binding and transport (e.g., heme group, an iron–porphyrin complex, responsible for animal cellular respiration), and bacteria photosynthesis. The pivotal functions fulfilled by these naturally occurring porphyrinoids have motivated and inspired organic chemists to produce synthetic porphyrins and analogs in the laboratory. In recent years, a multitude of applications for porphyrins has shifted the focus from purely academic interest to industrial processes. There is a growing recognition of the need to develop new, more selective, and environmentally friendly synthetic methods. Within this Special Issue, readers will find a collection of 16 original research papers and a comprehensive review, all dedicated to exploring the synthesis and functionalization of tetrapyrrolic macrocycles. These papers shed light on the vast potential applications of these compounds across various fields. 2023-11-30T20:55:56Z 2023-11-30T20:55:56Z 2023 book ONIX_20231130_9783036594002_272 9783036594002 9783036594019 https://directory.doabooks.org/handle/20.500.12854/128820 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/8288 https://mdpi.com/books/pdfview/book/8288 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9401-9 10.3390/books978-3-0365-9401-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036594002 9783036594019 298 Basel open access
spellingShingle porphyrin
human serum albumin
spectroscopy
molecular docking
chemical-biological interactions
Spirulina maxima
chlorophyll a derivatives
photosensitizers
semisynthesis
photodynamic inactivation
array
artificial photosynthesis
building block
copper-free Sonogashira coupling
ethyne
perylene
solar
carboxylated pyrrolidine-fused chlorin
fluorescence
glutathione detection
porphyrin macrocycles
photodynamic therapy
theranostic agents
corroles
trans-A2B-corroles
photophysics
photobiology
asymmetrical porphyrins
human U937 monocytic cells
transmembrane potential
membrane anisotropy
sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2b)
Slo1
SUR2
asymmetric catalysis
Diels–Alder reaction
imidazolidin-4-ones
organocatalysis
photocatalysis
porphyrins
reductive amination
sulfonamides
MRSA
antimicrobial resistance
photosensitizer
singlet oxygen
potassium iodide
gram-positive bacteria
Staphylococcus aureus
copper-64
positron emission tomography
circular dichroism
chirality
chiral layers
supramolecular chirality
reflectance anisotropy spectroscopy
DFT
organometallic
density functionals
transition metals
green chemistry
C-H functionalization
epoxidation
iron porphyrin
oxidation catalysis
renewable aromatics
phthalocyanines
solubility
gas sensors
quartz microbalances
porphyrinoids
phenothiazine
radical cation
EPR spectroscopy
ENDOR
HYSCORE
spectroelectrochemistry
BODIPY
pyridyl
nitro
chloro
methyl ester
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PN Chemistry
thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
Porphyrin-Based Compounds: Synthesis and Application
title Porphyrin-Based Compounds: Synthesis and Application
title_full Porphyrin-Based Compounds: Synthesis and Application
title_fullStr Porphyrin-Based Compounds: Synthesis and Application
title_full_unstemmed Porphyrin-Based Compounds: Synthesis and Application
title_short Porphyrin-Based Compounds: Synthesis and Application
title_sort porphyrin based compounds synthesis and application
topic porphyrin
human serum albumin
spectroscopy
molecular docking
chemical-biological interactions
Spirulina maxima
chlorophyll a derivatives
photosensitizers
semisynthesis
photodynamic inactivation
array
artificial photosynthesis
building block
copper-free Sonogashira coupling
ethyne
perylene
solar
carboxylated pyrrolidine-fused chlorin
fluorescence
glutathione detection
porphyrin macrocycles
photodynamic therapy
theranostic agents
corroles
trans-A2B-corroles
photophysics
photobiology
asymmetrical porphyrins
human U937 monocytic cells
transmembrane potential
membrane anisotropy
sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2b)
Slo1
SUR2
asymmetric catalysis
Diels–Alder reaction
imidazolidin-4-ones
organocatalysis
photocatalysis
porphyrins
reductive amination
sulfonamides
MRSA
antimicrobial resistance
photosensitizer
singlet oxygen
potassium iodide
gram-positive bacteria
Staphylococcus aureus
copper-64
positron emission tomography
circular dichroism
chirality
chiral layers
supramolecular chirality
reflectance anisotropy spectroscopy
DFT
organometallic
density functionals
transition metals
green chemistry
C-H functionalization
epoxidation
iron porphyrin
oxidation catalysis
renewable aromatics
phthalocyanines
solubility
gas sensors
quartz microbalances
porphyrinoids
phenothiazine
radical cation
EPR spectroscopy
ENDOR
HYSCORE
spectroelectrochemistry
BODIPY
pyridyl
nitro
chloro
methyl ester
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PN Chemistry
thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
topic_facet porphyrin
human serum albumin
spectroscopy
molecular docking
chemical-biological interactions
Spirulina maxima
chlorophyll a derivatives
photosensitizers
semisynthesis
photodynamic inactivation
array
artificial photosynthesis
building block
copper-free Sonogashira coupling
ethyne
perylene
solar
carboxylated pyrrolidine-fused chlorin
fluorescence
glutathione detection
porphyrin macrocycles
photodynamic therapy
theranostic agents
corroles
trans-A2B-corroles
photophysics
photobiology
asymmetrical porphyrins
human U937 monocytic cells
transmembrane potential
membrane anisotropy
sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2b)
Slo1
SUR2
asymmetric catalysis
Diels–Alder reaction
imidazolidin-4-ones
organocatalysis
photocatalysis
porphyrins
reductive amination
sulfonamides
MRSA
antimicrobial resistance
photosensitizer
singlet oxygen
potassium iodide
gram-positive bacteria
Staphylococcus aureus
copper-64
positron emission tomography
circular dichroism
chirality
chiral layers
supramolecular chirality
reflectance anisotropy spectroscopy
DFT
organometallic
density functionals
transition metals
green chemistry
C-H functionalization
epoxidation
iron porphyrin
oxidation catalysis
renewable aromatics
phthalocyanines
solubility
gas sensors
quartz microbalances
porphyrinoids
phenothiazine
radical cation
EPR spectroscopy
ENDOR
HYSCORE
spectroelectrochemistry
BODIPY
pyridyl
nitro
chloro
methyl ester
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PN Chemistry
thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
url ONIX_20231130_9783036594002_272