Cavitation-Enhanced Drug Delivery and Immunotherapy

Cavitation-Enhanced Drug Delivery and Immunotherapy is a rapidly evolving area that has been buoyed in recent years by the development of methods harnessing the activity of ultrasound-stimulated bubbles, known as cavitation. When properly controlled, cavitation can help overcome physical barriers to...

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Idioma:inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2023
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collection Directory of Open Access Books
description Cavitation-Enhanced Drug Delivery and Immunotherapy is a rapidly evolving area that has been buoyed in recent years by the development of methods harnessing the activity of ultrasound-stimulated bubbles, known as cavitation. When properly controlled, cavitation can help overcome physical barriers to drug delivery whilst providing readily measurable information for timely quantitative feedback and treatment guidance. Microbubble-assisted therapies have demonstrated impressive advancements in clinical trials and pre-clinical areas, including applications in neurology, oncology, cardiology and beyond.
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id doab-20.500.12854ir-128825
institution Directory of Open Access Books
language eng
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-1288252024-04-11T15:11:12Z Cavitation-Enhanced Drug Delivery and Immunotherapy Helfield, Brandon Sirsi, Shashank Kwan, James Gray, Michael passive cavitation detection size-isolated microbubbles focused ultrasound stable cavitation inertial cavitation perfluoropentane microdroplets cavitation microfluidic emulsion manufacturing polydispersity ultrasound contrast agent ultrasound duty cycle intravascular ultrasound ultrasound targeted drug delivery microbubble sonoporation nanoparticle gene therapy miRNA delivery microRNA-126 microbubbles endothelial cells HUVEC therapeutic angiogenesis round window membrane metabolomics perilymph inner ear SonoCloud GL261 mouse model ultrasound-mediated drug delivery glioblastoma immune checkpoint inhibitors radiotherapy tumor hypoxia contrast-enhanced ultrasound oxygen-loaded microbubbles drug delivery head and neck cancer lonidamine metformin cavitation nuclei Biofilm microbubble targeting cationic microbubble ultrasound drug delivery pancreatic cancer paclitaxel gemcitabine cetuximab SonoTran Particles passive acoustic mapping large animal cancer model targeted microbubbles ultrasound imaging probes ultrasound-targeted delivery therapy immunotherapy ultrasound targeting acoustic droplet vaporization cancer checkpoint inhibitor n/a thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology Cavitation-Enhanced Drug Delivery and Immunotherapy is a rapidly evolving area that has been buoyed in recent years by the development of methods harnessing the activity of ultrasound-stimulated bubbles, known as cavitation. When properly controlled, cavitation can help overcome physical barriers to drug delivery whilst providing readily measurable information for timely quantitative feedback and treatment guidance. Microbubble-assisted therapies have demonstrated impressive advancements in clinical trials and pre-clinical areas, including applications in neurology, oncology, cardiology and beyond. 2023-11-30T20:56:21Z 2023-11-30T20:56:21Z 2023 book ONIX_20231130_9783036594347_277 9783036594347 9783036594354 https://directory.doabooks.org/handle/20.500.12854/128825 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/8293 https://mdpi.com/books/pdfview/book/8293 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9435-4 10.3390/books978-3-0365-9435-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036594347 9783036594354 260 Basel open access
spellingShingle passive cavitation detection
size-isolated microbubbles
focused ultrasound
stable cavitation
inertial cavitation
perfluoropentane microdroplets
cavitation
microfluidic emulsion manufacturing
polydispersity
ultrasound contrast agent
ultrasound duty cycle
intravascular ultrasound
ultrasound
targeted drug delivery
microbubble
sonoporation
nanoparticle
gene therapy
miRNA delivery
microRNA-126
microbubbles
endothelial cells
HUVEC
therapeutic angiogenesis
round window membrane
metabolomics
perilymph
inner ear
SonoCloud
GL261 mouse model
ultrasound-mediated drug delivery
glioblastoma
immune checkpoint inhibitors
radiotherapy
tumor hypoxia
contrast-enhanced ultrasound
oxygen-loaded microbubbles
drug delivery
head and neck cancer
lonidamine
metformin
cavitation nuclei
Biofilm
microbubble targeting
cationic microbubble
ultrasound drug delivery
pancreatic cancer
paclitaxel
gemcitabine
cetuximab
SonoTran Particles
passive acoustic mapping
large animal cancer model
targeted microbubbles
ultrasound imaging probes
ultrasound-targeted delivery
therapy
immunotherapy
ultrasound targeting
acoustic droplet vaporization
cancer
checkpoint inhibitor
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
Cavitation-Enhanced Drug Delivery and Immunotherapy
title Cavitation-Enhanced Drug Delivery and Immunotherapy
title_full Cavitation-Enhanced Drug Delivery and Immunotherapy
title_fullStr Cavitation-Enhanced Drug Delivery and Immunotherapy
title_full_unstemmed Cavitation-Enhanced Drug Delivery and Immunotherapy
title_short Cavitation-Enhanced Drug Delivery and Immunotherapy
title_sort cavitation enhanced drug delivery and immunotherapy
topic passive cavitation detection
size-isolated microbubbles
focused ultrasound
stable cavitation
inertial cavitation
perfluoropentane microdroplets
cavitation
microfluidic emulsion manufacturing
polydispersity
ultrasound contrast agent
ultrasound duty cycle
intravascular ultrasound
ultrasound
targeted drug delivery
microbubble
sonoporation
nanoparticle
gene therapy
miRNA delivery
microRNA-126
microbubbles
endothelial cells
HUVEC
therapeutic angiogenesis
round window membrane
metabolomics
perilymph
inner ear
SonoCloud
GL261 mouse model
ultrasound-mediated drug delivery
glioblastoma
immune checkpoint inhibitors
radiotherapy
tumor hypoxia
contrast-enhanced ultrasound
oxygen-loaded microbubbles
drug delivery
head and neck cancer
lonidamine
metformin
cavitation nuclei
Biofilm
microbubble targeting
cationic microbubble
ultrasound drug delivery
pancreatic cancer
paclitaxel
gemcitabine
cetuximab
SonoTran Particles
passive acoustic mapping
large animal cancer model
targeted microbubbles
ultrasound imaging probes
ultrasound-targeted delivery
therapy
immunotherapy
ultrasound targeting
acoustic droplet vaporization
cancer
checkpoint inhibitor
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
topic_facet passive cavitation detection
size-isolated microbubbles
focused ultrasound
stable cavitation
inertial cavitation
perfluoropentane microdroplets
cavitation
microfluidic emulsion manufacturing
polydispersity
ultrasound contrast agent
ultrasound duty cycle
intravascular ultrasound
ultrasound
targeted drug delivery
microbubble
sonoporation
nanoparticle
gene therapy
miRNA delivery
microRNA-126
microbubbles
endothelial cells
HUVEC
therapeutic angiogenesis
round window membrane
metabolomics
perilymph
inner ear
SonoCloud
GL261 mouse model
ultrasound-mediated drug delivery
glioblastoma
immune checkpoint inhibitors
radiotherapy
tumor hypoxia
contrast-enhanced ultrasound
oxygen-loaded microbubbles
drug delivery
head and neck cancer
lonidamine
metformin
cavitation nuclei
Biofilm
microbubble targeting
cationic microbubble
ultrasound drug delivery
pancreatic cancer
paclitaxel
gemcitabine
cetuximab
SonoTran Particles
passive acoustic mapping
large animal cancer model
targeted microbubbles
ultrasound imaging probes
ultrasound-targeted delivery
therapy
immunotherapy
ultrasound targeting
acoustic droplet vaporization
cancer
checkpoint inhibitor
n/a
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
url ONIX_20231130_9783036594347_277