Therapeutic Landscapes in Colorectal Carcinoma
The Special Issue, titled “Therapeutic Landscapes in Colorectal Carcinoma”, illustrates a stimulating collection of articles written by international specialists that can promote discussions and ideas among colleagues working on CRC. It provides us with a deeper insight into the latest advances invo...
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| 格式: | Online |
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| 語言: | 英语 |
| 出版: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
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| 主題: | |
| 在線閱讀: | ONIX_20231130_9783036594415_281 |
| 標簽: |
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| _version_ | 1869514619987427328 |
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| collection | Directory of Open Access Books |
| description | The Special Issue, titled “Therapeutic Landscapes in Colorectal Carcinoma”, illustrates a stimulating collection of articles written by international specialists that can promote discussions and ideas among colleagues working on CRC. It provides us with a deeper insight into the latest advances involving knowledge on CRC from scientific, translational, and clinical points of view. Through this Special Issue, our main purpose was to shed light on some state-of-the-art research on CRC. Here, the reader will find papers on prognostic factors as well as responses to neoadjuvant and adjuvant CRC treatments. Finally, we discuss the research trends and hotspots for CRC therapies that emerged during the COVID-19 pandemic, such as the potential achievement of a transition from CRC clinical research to precision medicine, together with a special emphasis given to new single-cell-based techniques. We hope that it can encourage translational and interdisciplinary collaborations, leading to a definitive understanding of strategies to overcome and inhibit CRC progression and metastasis. |
| format | Online |
| id | doab-20.500.12854ir-128829 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1288292024-03-31T13:10:36Z Therapeutic Landscapes in Colorectal Carcinoma Scanu, Antonio M De Miglio, Maria Rosaria colorectal cancer inflammatory pathways NFKB RIPK2 MSI dMMR colorectal cancer immunotherapy Romania incidence PCR IHC drug development targeted therapies preclinical candidates databases cancer therapeutics TGF-b regorafenib colorectal carcinoma intratumor heterogeneity single-cell next-generation sequencing precision medicine metastatic colorectal cancer BRAF mutation triple target therapy colorectal cancer screening COVID-19 SARS-CoV-2 colon cancer cell line models dependencies targeted therapy signal transduction neoadjuvant chemotherapy (NAC) locally advanced colon cancer (LACC) preoperative treatment propensity score matching survival liver transplantation de novo malignancy immunosuppression uracil–tegafur chemotherapy adjuvant therapy stage IIA n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology The Special Issue, titled “Therapeutic Landscapes in Colorectal Carcinoma”, illustrates a stimulating collection of articles written by international specialists that can promote discussions and ideas among colleagues working on CRC. It provides us with a deeper insight into the latest advances involving knowledge on CRC from scientific, translational, and clinical points of view. Through this Special Issue, our main purpose was to shed light on some state-of-the-art research on CRC. Here, the reader will find papers on prognostic factors as well as responses to neoadjuvant and adjuvant CRC treatments. Finally, we discuss the research trends and hotspots for CRC therapies that emerged during the COVID-19 pandemic, such as the potential achievement of a transition from CRC clinical research to precision medicine, together with a special emphasis given to new single-cell-based techniques. We hope that it can encourage translational and interdisciplinary collaborations, leading to a definitive understanding of strategies to overcome and inhibit CRC progression and metastasis. 2023-11-30T20:56:39Z 2023-11-30T20:56:39Z 2023 book ONIX_20231130_9783036594415_281 9783036594415 9783036594408 https://directory.doabooks.org/handle/20.500.12854/128829 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/8298 https://mdpi.com/books/pdfview/book/8298 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9440-8 10.3390/books978-3-0365-9440-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036594415 9783036594408 142 Basel open access |
| spellingShingle | colorectal cancer inflammatory pathways NFKB RIPK2 MSI dMMR colorectal cancer immunotherapy Romania incidence PCR IHC drug development targeted therapies preclinical candidates databases cancer therapeutics TGF-b regorafenib colorectal carcinoma intratumor heterogeneity single-cell next-generation sequencing precision medicine metastatic colorectal cancer BRAF mutation triple target therapy colorectal cancer screening COVID-19 SARS-CoV-2 colon cancer cell line models dependencies targeted therapy signal transduction neoadjuvant chemotherapy (NAC) locally advanced colon cancer (LACC) preoperative treatment propensity score matching survival liver transplantation de novo malignancy immunosuppression uracil–tegafur chemotherapy adjuvant therapy stage IIA n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Therapeutic Landscapes in Colorectal Carcinoma |
| title | Therapeutic Landscapes in Colorectal Carcinoma |
| title_full | Therapeutic Landscapes in Colorectal Carcinoma |
| title_fullStr | Therapeutic Landscapes in Colorectal Carcinoma |
| title_full_unstemmed | Therapeutic Landscapes in Colorectal Carcinoma |
| title_short | Therapeutic Landscapes in Colorectal Carcinoma |
| title_sort | therapeutic landscapes in colorectal carcinoma |
| topic | colorectal cancer inflammatory pathways NFKB RIPK2 MSI dMMR colorectal cancer immunotherapy Romania incidence PCR IHC drug development targeted therapies preclinical candidates databases cancer therapeutics TGF-b regorafenib colorectal carcinoma intratumor heterogeneity single-cell next-generation sequencing precision medicine metastatic colorectal cancer BRAF mutation triple target therapy colorectal cancer screening COVID-19 SARS-CoV-2 colon cancer cell line models dependencies targeted therapy signal transduction neoadjuvant chemotherapy (NAC) locally advanced colon cancer (LACC) preoperative treatment propensity score matching survival liver transplantation de novo malignancy immunosuppression uracil–tegafur chemotherapy adjuvant therapy stage IIA n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | colorectal cancer inflammatory pathways NFKB RIPK2 MSI dMMR colorectal cancer immunotherapy Romania incidence PCR IHC drug development targeted therapies preclinical candidates databases cancer therapeutics TGF-b regorafenib colorectal carcinoma intratumor heterogeneity single-cell next-generation sequencing precision medicine metastatic colorectal cancer BRAF mutation triple target therapy colorectal cancer screening COVID-19 SARS-CoV-2 colon cancer cell line models dependencies targeted therapy signal transduction neoadjuvant chemotherapy (NAC) locally advanced colon cancer (LACC) preoperative treatment propensity score matching survival liver transplantation de novo malignancy immunosuppression uracil–tegafur chemotherapy adjuvant therapy stage IIA n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20231130_9783036594415_281 |