Breast Cancer—Therapeutic Challenges, Research Strategies and Novel Diagnostics
Thanks to the breast cancer research of recent decades, effective methods and strategies have been established, allowing the mortality rates of breast cancer patients to decrease more and more. However, we still face many challenges. The role of certain biomarkers or mutations is still not clear for...
Sábháilte in:
| Formáid: | Online |
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| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
MDPI - Multidisciplinary Digital Publishing Institute
2023
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| Ábhair: | |
| Rochtain ar líne: | ONIX_20231130_9783036594439_282 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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| _version_ | 1869519825889394688 |
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| collection | Directory of Open Access Books |
| description | Thanks to the breast cancer research of recent decades, effective methods and strategies have been established, allowing the mortality rates of breast cancer patients to decrease more and more. However, we still face many challenges. The role of certain biomarkers or mutations is still not clear for treatment and surveillance. Novel drugs are often associated with a different spectrum of adverse events than that seen for conventional therapies, accordingly having an impact on patients’ compliance behaviors. In breast cancer surgery, in some cases, the question remains whether to escalate or deescalate. Additionally, with regard to diagnostics, in a digitalized world, home-based tools and therapy monitoring options are of high importance, especially under the tough conditions and supply problems seen during the COVID-19 pandemic.This Special Issue gathers original research articles and reviews demonstrating therapeutic challenges, current research strategies, and novel diagnostics in breast cancer. |
| format | Online |
| id | doab-20.500.12854ir-128830 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1288302024-03-30T23:22:34Z Breast Cancer—Therapeutic Challenges, Research Strategies and Novel Diagnostics Nabieva, Naiba pannexin 1 (PANX1) neutrophils adenosine tumor microenvironment (TME) breast cancer ER heterogeneity 18F-FES PET/CT diagnosis treatment pattern metastatic breast cancer heterogeneity HER2 18F-fluorodeoxyglucose positron emission tomography/computed tomography pyrotinib therapy response oncotype DX recurrence score individualized therapy advanced breast cancer breast cancer susceptibility genes 1 and 2 genetic testing human epidermal growth factor receptor 2—negative poly(adenosine diphosphate-ribose) polymerase inhibitors real-world machine learning neoadjuvant systemic treatment lymph node metastasis phytochemicals nanocarriers chemotherapy drug resistance risk prediction models breast cancer screening risk assessment risk-based screening localization technique non-palpable lesion intraoperative ultrasound wire-guided localization magnetic seed radioactive seed radar reflector radiofrequency identification tag oncology telemedicine telerehabilitation psychological well-being cognitive impairment rehabilitation cancer side effects metastasis treatment human epidermal growth factor receptor 2 hormone receptor registries endocrine treatment CDK4/6 inhibitor abemaciclib dalpiciclib palbociclib ribociclib Contrast-Enhanced Mammography Digital Breast Tomosynthesis Average Glandular Dose TNBC LEMD1 ERK therapeutic target BOUNCE coping self-efficacy fear of cancer recurrence latent growth modeling trajectories n/a thema EDItEUR::M Medicine and Nursing Thanks to the breast cancer research of recent decades, effective methods and strategies have been established, allowing the mortality rates of breast cancer patients to decrease more and more. However, we still face many challenges. The role of certain biomarkers or mutations is still not clear for treatment and surveillance. Novel drugs are often associated with a different spectrum of adverse events than that seen for conventional therapies, accordingly having an impact on patients’ compliance behaviors. In breast cancer surgery, in some cases, the question remains whether to escalate or deescalate. Additionally, with regard to diagnostics, in a digitalized world, home-based tools and therapy monitoring options are of high importance, especially under the tough conditions and supply problems seen during the COVID-19 pandemic.This Special Issue gathers original research articles and reviews demonstrating therapeutic challenges, current research strategies, and novel diagnostics in breast cancer. 2023-11-30T20:56:44Z 2023-11-30T20:56:44Z 2023 book ONIX_20231130_9783036594439_282 9783036594439 9783036594422 https://directory.doabooks.org/handle/20.500.12854/128830 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/8299 https://mdpi.com/books/pdfview/book/8299 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9442-2 10.3390/books978-3-0365-9442-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036594439 9783036594422 282 Basel open access |
| spellingShingle | pannexin 1 (PANX1) neutrophils adenosine tumor microenvironment (TME) breast cancer ER heterogeneity 18F-FES PET/CT diagnosis treatment pattern metastatic breast cancer heterogeneity HER2 18F-fluorodeoxyglucose positron emission tomography/computed tomography pyrotinib therapy response oncotype DX recurrence score individualized therapy advanced breast cancer breast cancer susceptibility genes 1 and 2 genetic testing human epidermal growth factor receptor 2—negative poly(adenosine diphosphate-ribose) polymerase inhibitors real-world machine learning neoadjuvant systemic treatment lymph node metastasis phytochemicals nanocarriers chemotherapy drug resistance risk prediction models breast cancer screening risk assessment risk-based screening localization technique non-palpable lesion intraoperative ultrasound wire-guided localization magnetic seed radioactive seed radar reflector radiofrequency identification tag oncology telemedicine telerehabilitation psychological well-being cognitive impairment rehabilitation cancer side effects metastasis treatment human epidermal growth factor receptor 2 hormone receptor registries endocrine treatment CDK4/6 inhibitor abemaciclib dalpiciclib palbociclib ribociclib Contrast-Enhanced Mammography Digital Breast Tomosynthesis Average Glandular Dose TNBC LEMD1 ERK therapeutic target BOUNCE coping self-efficacy fear of cancer recurrence latent growth modeling trajectories n/a thema EDItEUR::M Medicine and Nursing Breast Cancer—Therapeutic Challenges, Research Strategies and Novel Diagnostics |
| title | Breast Cancer—Therapeutic Challenges, Research Strategies and Novel Diagnostics |
| title_full | Breast Cancer—Therapeutic Challenges, Research Strategies and Novel Diagnostics |
| title_fullStr | Breast Cancer—Therapeutic Challenges, Research Strategies and Novel Diagnostics |
| title_full_unstemmed | Breast Cancer—Therapeutic Challenges, Research Strategies and Novel Diagnostics |
| title_short | Breast Cancer—Therapeutic Challenges, Research Strategies and Novel Diagnostics |
| title_sort | breast cancer therapeutic challenges research strategies and novel diagnostics |
| topic | pannexin 1 (PANX1) neutrophils adenosine tumor microenvironment (TME) breast cancer ER heterogeneity 18F-FES PET/CT diagnosis treatment pattern metastatic breast cancer heterogeneity HER2 18F-fluorodeoxyglucose positron emission tomography/computed tomography pyrotinib therapy response oncotype DX recurrence score individualized therapy advanced breast cancer breast cancer susceptibility genes 1 and 2 genetic testing human epidermal growth factor receptor 2—negative poly(adenosine diphosphate-ribose) polymerase inhibitors real-world machine learning neoadjuvant systemic treatment lymph node metastasis phytochemicals nanocarriers chemotherapy drug resistance risk prediction models breast cancer screening risk assessment risk-based screening localization technique non-palpable lesion intraoperative ultrasound wire-guided localization magnetic seed radioactive seed radar reflector radiofrequency identification tag oncology telemedicine telerehabilitation psychological well-being cognitive impairment rehabilitation cancer side effects metastasis treatment human epidermal growth factor receptor 2 hormone receptor registries endocrine treatment CDK4/6 inhibitor abemaciclib dalpiciclib palbociclib ribociclib Contrast-Enhanced Mammography Digital Breast Tomosynthesis Average Glandular Dose TNBC LEMD1 ERK therapeutic target BOUNCE coping self-efficacy fear of cancer recurrence latent growth modeling trajectories n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | pannexin 1 (PANX1) neutrophils adenosine tumor microenvironment (TME) breast cancer ER heterogeneity 18F-FES PET/CT diagnosis treatment pattern metastatic breast cancer heterogeneity HER2 18F-fluorodeoxyglucose positron emission tomography/computed tomography pyrotinib therapy response oncotype DX recurrence score individualized therapy advanced breast cancer breast cancer susceptibility genes 1 and 2 genetic testing human epidermal growth factor receptor 2—negative poly(adenosine diphosphate-ribose) polymerase inhibitors real-world machine learning neoadjuvant systemic treatment lymph node metastasis phytochemicals nanocarriers chemotherapy drug resistance risk prediction models breast cancer screening risk assessment risk-based screening localization technique non-palpable lesion intraoperative ultrasound wire-guided localization magnetic seed radioactive seed radar reflector radiofrequency identification tag oncology telemedicine telerehabilitation psychological well-being cognitive impairment rehabilitation cancer side effects metastasis treatment human epidermal growth factor receptor 2 hormone receptor registries endocrine treatment CDK4/6 inhibitor abemaciclib dalpiciclib palbociclib ribociclib Contrast-Enhanced Mammography Digital Breast Tomosynthesis Average Glandular Dose TNBC LEMD1 ERK therapeutic target BOUNCE coping self-efficacy fear of cancer recurrence latent growth modeling trajectories n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20231130_9783036594439_282 |