Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis
The scientific monograph by the author Peter Mikus entitled "Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis" provides a comprehensive view on the advanced capillary electrophoresis techniques aimed to current chiral bioanalysis. The advances in the chiral electrop...
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| Định dạng: | Online |
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| Ngôn ngữ: | Tiếng Anh |
| Được phát hành: |
IntechOpen
2023
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| Những chủ đề: | |
| Truy cập trực tuyến: | ONIX_20231201_9789535106579_305 |
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| _version_ | 1869527072421969920 |
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| collection | Directory of Open Access Books |
| description | The scientific monograph by the author Peter Mikus entitled "Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis" provides a comprehensive view on the advanced capillary electrophoresis techniques aimed to current chiral bioanalysis. The advances in the chiral electrophoresis analytical approaches are divided and theoretically described in three sections involving (i) advanced chiral separations for the optimization of chiral resolution (separation mechanisms; electrophoresis techniques in capillary and microchip format; electrophoretic modes such as ITP, CZE/EKC, CEC; chiral additives / pseudophases / phases), (ii) advanced sample preparation for the on-line preconcentration, sample clean-up and analyte derivatization (implementation of electrophoretic effects such as stacking; non-electrophoretic effects such as SPE, chromatography, dialysis; combinations of these effects; multidimensional CE systems; instrumental schemes), (iii) advanced combinations of detection and electrophoresis for the optimization in qualitative and quantitative evaluation (the most important universal as well as selective detection approaches such as absorption and fluorescence spectrophotometry, electrochemical detection, mass spectrometry vs. (i) and/or (ii)). Real analytical potential (benefits and limitations) of these advanced analytical approaches is emphasized by selected performance parameters of the methods and illustrated by many current practical applications including chiral analyses of drugs, their (bio)degradation products and biomarkers in pharmaceutical and biological matrices. The author wishes the readers many inspirations in the creation of new innovative approaches in the field of advanced chiral electrophoresis techniques with the aim to overcome capabilities of the current analytical techniques. |
| format | Online |
| id | doab-20.500.12854ir-129197 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1291972024-04-01T14:15:02Z Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis Mikus, Peter Pharmacology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology The scientific monograph by the author Peter Mikus entitled "Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis" provides a comprehensive view on the advanced capillary electrophoresis techniques aimed to current chiral bioanalysis. The advances in the chiral electrophoresis analytical approaches are divided and theoretically described in three sections involving (i) advanced chiral separations for the optimization of chiral resolution (separation mechanisms; electrophoresis techniques in capillary and microchip format; electrophoretic modes such as ITP, CZE/EKC, CEC; chiral additives / pseudophases / phases), (ii) advanced sample preparation for the on-line preconcentration, sample clean-up and analyte derivatization (implementation of electrophoretic effects such as stacking; non-electrophoretic effects such as SPE, chromatography, dialysis; combinations of these effects; multidimensional CE systems; instrumental schemes), (iii) advanced combinations of detection and electrophoresis for the optimization in qualitative and quantitative evaluation (the most important universal as well as selective detection approaches such as absorption and fluorescence spectrophotometry, electrochemical detection, mass spectrometry vs. (i) and/or (ii)). Real analytical potential (benefits and limitations) of these advanced analytical approaches is emphasized by selected performance parameters of the methods and illustrated by many current practical applications including chiral analyses of drugs, their (bio)degradation products and biomarkers in pharmaceutical and biological matrices. The author wishes the readers many inspirations in the creation of new innovative approaches in the field of advanced chiral electrophoresis techniques with the aim to overcome capabilities of the current analytical techniques. 2023-12-01T15:00:14Z 2023-12-01T15:00:14Z 2012 book ONIX_20231201_9789535106579_305 9789535106579 9789535170266 https://directory.doabooks.org/handle/20.500.12854/129197 eng image/jpeg n/a https://www.intechopen.com/books/2993 https://mts.intechopen.com/storage/books/2993/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/3321 10.5772/3321 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535106579 9789535170266 IntechOpen 210 open access |
| spellingShingle | Pharmacology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis |
| title | Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis |
| title_full | Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis |
| title_fullStr | Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis |
| title_full_unstemmed | Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis |
| title_short | Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis |
| title_sort | chiral capillary electrophoresis in current pharmaceutical and biomedical analysis |
| topic | Pharmacology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| topic_facet | Pharmacology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| url | ONIX_20231201_9789535106579_305 |