The Transcription Factor Nrf2
Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. The...
Guardado en:
| Formato: | Online |
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| Lenguaje: | inglés |
| Publicado: |
IntechOpen
2023
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| Materias: | |
| Acceso en línea: | ONIX_20231201_9789535128380_426 |
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| _version_ | 1869516597810429952 |
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| collection | Directory of Open Access Books |
| description | Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways. |
| format | Online |
| id | doab-20.500.12854ir-129317 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1293172024-04-05T17:30:55Z The Transcription Factor Nrf2 Antonio Morales-Gonzalez, Jose Morales-Gonzalez, Angel Osiris Madrigal-Santillan, Eduardo Proteins thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways. 2023-12-01T15:11:11Z 2023-12-01T15:11:11Z 2016 book ONIX_20231201_9789535128380_426 9789535128380 9789535128373 9789535154624 https://directory.doabooks.org/handle/20.500.12854/129317 eng image/jpeg n/a https://www.intechopen.com/books/5407 https://mts.intechopen.com/storage/books/5407/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/62743 10.5772/62743 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535128380 9789535128373 9789535154624 IntechOpen 210 open access |
| spellingShingle | Proteins thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology The Transcription Factor Nrf2 |
| title | The Transcription Factor Nrf2 |
| title_full | The Transcription Factor Nrf2 |
| title_fullStr | The Transcription Factor Nrf2 |
| title_full_unstemmed | The Transcription Factor Nrf2 |
| title_short | The Transcription Factor Nrf2 |
| title_sort | transcription factor nrf2 |
| topic | Proteins thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology |
| topic_facet | Proteins thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology |
| url | ONIX_20231201_9789535128380_426 |