Telomere

This book, Telomere - A Complex End of a Chromosome, is organized into nine chapters containing the latest aspects of the current knowledge about the structure of telomeres and the crucial role that telomerase plays not only in maintaining chromosomal stability but also in relation to cell immortali...

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פורמט: Online
שפה:אנגלית
יצא לאור: IntechOpen 2023
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גישה מקוונת:ONIX_20231201_9789535127536_454
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collection Directory of Open Access Books
description This book, Telomere - A Complex End of a Chromosome, is organized into nine chapters containing the latest aspects of the current knowledge about the structure of telomeres and the crucial role that telomerase plays not only in maintaining chromosomal stability but also in relation to cell immortality, cell instability, and cancer biology. We now appreciate that these unusual complexes of DNA and proteins we all know as "telomeres" are dynamic and key structures that depend on telomerase and other cellular factors for continuance. Regulation of telomere activity is a dynamic area of current research, and new insights into telomeres and their role in aging and cancer, among other biological functions and pathologies, appear regularly in the scientific world. However, one fact is more than understandable in this difficult biological conundrum: the end of the telomere story is far from being totally unraveled.
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spelling doab-20.500.12854ir-1293452024-03-31T22:45:26Z Telomere Larramendy, Marcelo L. cancer, oxidative stress, biomarkers, chemotherapy, human health, transplantation thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics This book, Telomere - A Complex End of a Chromosome, is organized into nine chapters containing the latest aspects of the current knowledge about the structure of telomeres and the crucial role that telomerase plays not only in maintaining chromosomal stability but also in relation to cell immortality, cell instability, and cancer biology. We now appreciate that these unusual complexes of DNA and proteins we all know as "telomeres" are dynamic and key structures that depend on telomerase and other cellular factors for continuance. Regulation of telomere activity is a dynamic area of current research, and new insights into telomeres and their role in aging and cancer, among other biological functions and pathologies, appear regularly in the scientific world. However, one fact is more than understandable in this difficult biological conundrum: the end of the telomere story is far from being totally unraveled. 2023-12-01T15:14:40Z 2023-12-01T15:14:40Z 2016 book ONIX_20231201_9789535127536_454 9789535127536 9789535127529 9789535141501 https://directory.doabooks.org/handle/20.500.12854/129345 eng image/jpeg n/a https://www.intechopen.com/books/5085 https://mts.intechopen.com/storage/books/5085/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/60625 10.5772/60625 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535127536 9789535127529 9789535141501 IntechOpen 226 open access
spellingShingle cancer, oxidative stress, biomarkers, chemotherapy, human health, transplantation
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
Telomere
title Telomere
title_full Telomere
title_fullStr Telomere
title_full_unstemmed Telomere
title_short Telomere
title_sort telomere
topic cancer, oxidative stress, biomarkers, chemotherapy, human health, transplantation
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
topic_facet cancer, oxidative stress, biomarkers, chemotherapy, human health, transplantation
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
url ONIX_20231201_9789535127536_454