New Insights into Inflammatory Bowel Disease

The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknow...

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Pubblicazione: IntechOpen 2023
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collection Directory of Open Access Books
description The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown. However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation. This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed.
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spelling doab-20.500.12854ir-1293552024-03-31T22:44:25Z New Insights into Inflammatory Bowel Disease Huber, Samuel cytokines, crohn’s disease, ulcerative colitis, th17, epidemiology, pathogenesis thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology The incidence of chronic inflammatory and autoimmune diseases is steadily increasing. Inflammatory bowel disease (IBD) is one example of a chronic inflammatory disease, which primarily affects the intestine but may also affect extraintestinal organs. The exact pathogenesis of IBD is currently unknown. However, it is clear that the pathogenesis is complex, involving barrier defects, changes in the intestinal microbiome, and chronic immune activation. This book aims to summarize basic aspects of these complex interactions between barrier function, microbiome, and the immune system. Of note, there is currently no cure for IBD. However, several therapies have evolved in the last years, which are overall able to-at least temporarily-suppress IBD. These therapies and the underlying mechanism are discussed. 2023-12-01T15:15:43Z 2023-12-01T15:15:43Z 2016 book ONIX_20231201_9789535127550_464 9789535127550 9789535127543 9789535141679 https://directory.doabooks.org/handle/20.500.12854/129355 eng image/jpeg n/a https://www.intechopen.com/books/5204 https://mts.intechopen.com/storage/books/5204/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/61540 10.5772/61540 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535127550 9789535127543 9789535141679 IntechOpen 264 open access
spellingShingle cytokines, crohn’s disease, ulcerative colitis, th17, epidemiology, pathogenesis
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology
New Insights into Inflammatory Bowel Disease
title New Insights into Inflammatory Bowel Disease
title_full New Insights into Inflammatory Bowel Disease
title_fullStr New Insights into Inflammatory Bowel Disease
title_full_unstemmed New Insights into Inflammatory Bowel Disease
title_short New Insights into Inflammatory Bowel Disease
title_sort new insights into inflammatory bowel disease
topic cytokines, crohn’s disease, ulcerative colitis, th17, epidemiology, pathogenesis
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology
topic_facet cytokines, crohn’s disease, ulcerative colitis, th17, epidemiology, pathogenesis
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology
url ONIX_20231201_9789535127550_464