Osteosarcoma
Osteosarcoma is the most common malignant bone tumor and mainly affects children, adolescents, and young adults. Osteosarcoma shows significant genetic instability, resulting in very complex biology with multifaceted cellular and molecular mechanisms and behavior. Although clinical outcomes, both pr...
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| Format: | Online |
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| Sprache: | Englisch |
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IntechOpen
2023
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| Online-Zugang: | ONIX_20231201_9789535130963_651 |
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| _version_ | 1869514393557925888 |
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| collection | Directory of Open Access Books |
| description | Osteosarcoma is the most common malignant bone tumor and mainly affects children, adolescents, and young adults. Osteosarcoma shows significant genetic instability, resulting in very complex biology with multifaceted cellular and molecular mechanisms and behavior. Although clinical outcomes, both prognostic and functional, of osteosarcoma dramatically improved in the 1980s, the prognoses of the patients with relapsed and/or metastatic disease remained very poor in spite of our continuous efforts to overcome this difficulty. This book aims to delve into the current advances of basic and clinical sciences in osteosarcoma that are guiding the future directions of its research and clinical practice. The knowledge presented here will lead to further inspiration, ideas, and novel insights into the field of osteosarcoma research. Hopefully, this work will foster improvement of the prognosis for patients suffering from the disease. |
| format | Online |
| id | doab-20.500.12854ir-129542 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1295422024-04-01T14:12:26Z Osteosarcoma Honoki, Kanya Richard Weiss, Kurt chemotherapy, metastasis, microenvironment, genetics, biomarker, pathogenesis thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering::MQWP Prosthetics Osteosarcoma is the most common malignant bone tumor and mainly affects children, adolescents, and young adults. Osteosarcoma shows significant genetic instability, resulting in very complex biology with multifaceted cellular and molecular mechanisms and behavior. Although clinical outcomes, both prognostic and functional, of osteosarcoma dramatically improved in the 1980s, the prognoses of the patients with relapsed and/or metastatic disease remained very poor in spite of our continuous efforts to overcome this difficulty. This book aims to delve into the current advances of basic and clinical sciences in osteosarcoma that are guiding the future directions of its research and clinical practice. The knowledge presented here will lead to further inspiration, ideas, and novel insights into the field of osteosarcoma research. Hopefully, this work will foster improvement of the prognosis for patients suffering from the disease. 2023-12-01T15:37:02Z 2023-12-01T15:37:02Z 2017 book ONIX_20231201_9789535130963_651 9789535130963 9789535130956 9789535148593 https://directory.doabooks.org/handle/20.500.12854/129542 eng image/jpeg n/a https://www.intechopen.com/books/5399 https://mts.intechopen.com/storage/books/5399/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/62700 10.5772/62700 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535130963 9789535130956 9789535148593 IntechOpen 254 open access |
| spellingShingle | chemotherapy, metastasis, microenvironment, genetics, biomarker, pathogenesis thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering::MQWP Prosthetics Osteosarcoma |
| title | Osteosarcoma |
| title_full | Osteosarcoma |
| title_fullStr | Osteosarcoma |
| title_full_unstemmed | Osteosarcoma |
| title_short | Osteosarcoma |
| title_sort | osteosarcoma |
| topic | chemotherapy, metastasis, microenvironment, genetics, biomarker, pathogenesis thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering::MQWP Prosthetics |
| topic_facet | chemotherapy, metastasis, microenvironment, genetics, biomarker, pathogenesis thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering::MQWP Prosthetics |
| url | ONIX_20231201_9789535130963_651 |