Gluconeogenesis

Gluconeogenesis, the metabolic process through which glucose or glycogen is synthesized from noncarbohydrate substrates, is critical for maintaining the plasma glucose level within a narrow range either in the fed or fasting (nutritional deprivation) state. Dysregulation of this pathway usually caus...

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Jazyk:angličtina
Vydáno: IntechOpen 2023
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On-line přístup:ONIX_20231201_9789535133247_759
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collection Directory of Open Access Books
description Gluconeogenesis, the metabolic process through which glucose or glycogen is synthesized from noncarbohydrate substrates, is critical for maintaining the plasma glucose level within a narrow range either in the fed or fasting (nutritional deprivation) state. Dysregulation of this pathway usually causes severe or even fatal outcomes. This book discusses a series of up-to-date topics about this critical process, including the fundamental biochemical reactions of glucose metabolism, the glucogenesis process in eukaryotic cells using the Dictyostelium discoideum as a model, the role of "gut-brain-liver axis" in the control of glucose homeostasis, and the new mathematic model for the monitoring and prediction of blood glucose. This book is written by international scientists with expertise in the study of gluconeogenesis. By presenting a clear and succinct review of the fundamentals of gluconeogenesis, it is expected to draw more attentions and stimulate more scientists to dedicate their researches in revealing the mechanism and its application of gluconeogenesis.
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spelling doab-20.500.12854ir-1296502024-03-31T22:45:16Z Gluconeogenesis Zhang, Weizhen glucose homeostasis, diabetes mellitus, insulin, mathematical model, leptin, kidney thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology Gluconeogenesis, the metabolic process through which glucose or glycogen is synthesized from noncarbohydrate substrates, is critical for maintaining the plasma glucose level within a narrow range either in the fed or fasting (nutritional deprivation) state. Dysregulation of this pathway usually causes severe or even fatal outcomes. This book discusses a series of up-to-date topics about this critical process, including the fundamental biochemical reactions of glucose metabolism, the glucogenesis process in eukaryotic cells using the Dictyostelium discoideum as a model, the role of "gut-brain-liver axis" in the control of glucose homeostasis, and the new mathematic model for the monitoring and prediction of blood glucose. This book is written by international scientists with expertise in the study of gluconeogenesis. By presenting a clear and succinct review of the fundamentals of gluconeogenesis, it is expected to draw more attentions and stimulate more scientists to dedicate their researches in revealing the mechanism and its application of gluconeogenesis. 2023-12-01T15:52:12Z 2023-12-01T15:52:12Z 2017 book ONIX_20231201_9789535133247_759 9789535133247 9789535133230 9789535147312 https://directory.doabooks.org/handle/20.500.12854/129650 eng image/jpeg n/a https://www.intechopen.com/books/5614 https://mts.intechopen.com/storage/books/5614/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/63700 10.5772/63700 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535133247 9789535133230 9789535147312 IntechOpen 84 open access
spellingShingle glucose homeostasis, diabetes mellitus, insulin, mathematical model, leptin, kidney
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
Gluconeogenesis
title Gluconeogenesis
title_full Gluconeogenesis
title_fullStr Gluconeogenesis
title_full_unstemmed Gluconeogenesis
title_short Gluconeogenesis
title_sort gluconeogenesis
topic glucose homeostasis, diabetes mellitus, insulin, mathematical model, leptin, kidney
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
topic_facet glucose homeostasis, diabetes mellitus, insulin, mathematical model, leptin, kidney
thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
url ONIX_20231201_9789535133247_759