Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine

Umbilical cord blood (UCB) and, more recently, umbilical cord tissue (UCT) have been stored cryopreserved in private and public cord blood and tissue banks worldwide, since the umbilical cord blood was used for the first time in a child with Fanconi anemia with his HLA-identical sibling, following s...

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Мова:Англійська
Опубліковано: IntechOpen 2023
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Онлайн доступ:ONIX_20231201_9789535128663_791
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collection Directory of Open Access Books
description Umbilical cord blood (UCB) and, more recently, umbilical cord tissue (UCT) have been stored cryopreserved in private and public cord blood and tissue banks worldwide, since the umbilical cord blood was used for the first time in a child with Fanconi anemia with his HLA-identical sibling, following strict guidelines that imply high-quality standards and total rastreability of these units. The hematopoietic stem cells (HSCs) are clinically used in hematopoietic treatments for blood disorders and hemato-oncological diseases. Also, the mesenchymal stem cells (MSCs) isolated from the UCT and UCB, nowadays, can be used as coadjuvants of hematopoietic transplants. In the near future, these stem cells will have a crucial role in regenerative medicine. For this reason, these cells have been tested in several clinical trials and compassive treatments in children and adults, concerning a wide range of pathologies and diseases, for instance, for the treatment of cerebral paralysis. Considering the worldwide availability of UCB and UCT units and the absence of ethical concerns will probably become the best sources for cell-based therapies for hematological and nonhematological pathologies. The UCB will also have a crucial role in neonatology-predictive analysis in the near future.
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spelling doab-20.500.12854ir-1296822024-04-05T17:30:57Z Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine Colette Mauricio, Ana immunotherapy, electrospinning, graphene oxide, clinical trials, cerebral palsy, mesenchymal stem cells thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) Umbilical cord blood (UCB) and, more recently, umbilical cord tissue (UCT) have been stored cryopreserved in private and public cord blood and tissue banks worldwide, since the umbilical cord blood was used for the first time in a child with Fanconi anemia with his HLA-identical sibling, following strict guidelines that imply high-quality standards and total rastreability of these units. The hematopoietic stem cells (HSCs) are clinically used in hematopoietic treatments for blood disorders and hemato-oncological diseases. Also, the mesenchymal stem cells (MSCs) isolated from the UCT and UCB, nowadays, can be used as coadjuvants of hematopoietic transplants. In the near future, these stem cells will have a crucial role in regenerative medicine. For this reason, these cells have been tested in several clinical trials and compassive treatments in children and adults, concerning a wide range of pathologies and diseases, for instance, for the treatment of cerebral paralysis. Considering the worldwide availability of UCB and UCT units and the absence of ethical concerns will probably become the best sources for cell-based therapies for hematological and nonhematological pathologies. The UCB will also have a crucial role in neonatology-predictive analysis in the near future. 2023-12-01T15:57:40Z 2023-12-01T15:57:40Z 2017 book ONIX_20231201_9789535128663_791 9789535128663 9789535128656 9789535173311 https://directory.doabooks.org/handle/20.500.12854/129682 eng image/jpeg n/a https://www.intechopen.com/books/5369 https://mts.intechopen.com/storage/books/5369/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/62607 10.5772/62607 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535128663 9789535128656 9789535173311 IntechOpen 258 open access
spellingShingle immunotherapy, electrospinning, graphene oxide, clinical trials, cerebral palsy, mesenchymal stem cells
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine
title Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine
title_full Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine
title_fullStr Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine
title_full_unstemmed Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine
title_short Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine
title_sort umbilical cord blood banking for clinical application and regenerative medicine
topic immunotherapy, electrospinning, graphene oxide, clinical trials, cerebral palsy, mesenchymal stem cells
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
topic_facet immunotherapy, electrospinning, graphene oxide, clinical trials, cerebral palsy, mesenchymal stem cells
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
url ONIX_20231201_9789535128663_791