Neuroblastoma
Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-r...
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| Format: | Online |
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| Sprache: | Englisch |
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IntechOpen
2023
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| Online-Zugang: | ONIX_20231201_9789535135845_797 |
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| description | Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary objective of this book is to provide the readers with a comprehensive review of neuroblastoma, from clinical aspects and the currently available treatment to recent advancements and future directions in the field of NBL treatment. The topics and chapters have been compiled keeping in mind a diverse group of readers in different areas of specialty such as pediatric oncology, surgery, radiation oncology, and immunology, as well as physician scientists and basic researchers working in the field of neuroblastoma. |
| format | Online |
| id | doab-20.500.12854ir-129688 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1296882024-03-31T22:43:30Z Neuroblastoma Gowda, Chandrika inflammation, epidemiology, immunotherapy, epigenetics, genetics, targeted therapy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary objective of this book is to provide the readers with a comprehensive review of neuroblastoma, from clinical aspects and the currently available treatment to recent advancements and future directions in the field of NBL treatment. The topics and chapters have been compiled keeping in mind a diverse group of readers in different areas of specialty such as pediatric oncology, surgery, radiation oncology, and immunology, as well as physician scientists and basic researchers working in the field of neuroblastoma. 2023-12-01T15:58:21Z 2023-12-01T15:58:21Z 2017 book ONIX_20231201_9789535135845_797 9789535135845 9789535135838 9789535146193 https://directory.doabooks.org/handle/20.500.12854/129688 eng image/jpeg n/a https://www.intechopen.com/books/6006 https://mts.intechopen.com/storage/books/6006/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/66615 10.5772/66615 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535135845 9789535135838 9789535146193 IntechOpen 168 open access |
| spellingShingle | inflammation, epidemiology, immunotherapy, epigenetics, genetics, targeted therapy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Neuroblastoma |
| title | Neuroblastoma |
| title_full | Neuroblastoma |
| title_fullStr | Neuroblastoma |
| title_full_unstemmed | Neuroblastoma |
| title_short | Neuroblastoma |
| title_sort | neuroblastoma |
| topic | inflammation, epidemiology, immunotherapy, epigenetics, genetics, targeted therapy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | inflammation, epidemiology, immunotherapy, epigenetics, genetics, targeted therapy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20231201_9789535135845_797 |