Leishmaniases as Re-emerging Diseases
Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furth...
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| Format: | Online |
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| Language: | English |
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IntechOpen
2023
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| Online Access: | ONIX_20231201_9781789841022_1362 |
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| _version_ | 1869527157598846976 |
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| collection | Directory of Open Access Books |
| description | Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified. |
| format | Online |
| id | doab-20.500.12854ir-130253 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1302532024-03-31T22:45:45Z Leishmaniases as Re-emerging Diseases Afrin, Farhat Hemeg, Hassan leishmaniasis, visceral leishmaniasis, epidemiology, apoptosis, cytokines, chemotherapy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified. 2023-12-01T17:12:23Z 2023-12-01T17:12:23Z 2018 book ONIX_20231201_9781789841022_1362 9781789841022 9781789841015 9781838815219 https://directory.doabooks.org/handle/20.500.12854/130253 eng image/jpeg n/a https://www.intechopen.com/books/6520 https://mts.intechopen.com/storage/books/6520/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.71150 10.5772/intechopen.71150 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781789841022 9781789841015 9781838815219 IntechOpen 232 open access |
| spellingShingle | leishmaniasis, visceral leishmaniasis, epidemiology, apoptosis, cytokines, chemotherapy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases Leishmaniases as Re-emerging Diseases |
| title | Leishmaniases as Re-emerging Diseases |
| title_full | Leishmaniases as Re-emerging Diseases |
| title_fullStr | Leishmaniases as Re-emerging Diseases |
| title_full_unstemmed | Leishmaniases as Re-emerging Diseases |
| title_short | Leishmaniases as Re-emerging Diseases |
| title_sort | leishmaniases as re emerging diseases |
| topic | leishmaniasis, visceral leishmaniasis, epidemiology, apoptosis, cytokines, chemotherapy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases |
| topic_facet | leishmaniasis, visceral leishmaniasis, epidemiology, apoptosis, cytokines, chemotherapy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases |
| url | ONIX_20231201_9781789841022_1362 |