Non-Alcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) with a prevalence of 20-30% worldwide is characterized by the buildup of fat in the liver (liver steatosis) with no or little alcohol consumption. Its principal causes are modern diet and occidental lifestyle. It is characterized by metabolic disturbances suc...
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| Format: | Online |
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| Sprog: | engelsk |
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IntechOpen
2023
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| Online adgang: | ONIX_20231201_9789535139249_1406 |
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| _version_ | 1869527197543301120 |
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| collection | Directory of Open Access Books |
| description | Nonalcoholic fatty liver disease (NAFLD) with a prevalence of 20-30% worldwide is characterized by the buildup of fat in the liver (liver steatosis) with no or little alcohol consumption. Its principal causes are modern diet and occidental lifestyle. It is characterized by metabolic disturbances such as insulin resistance, inflammation, and oxidative stress, considered as the hepatic manifestation of metabolic syndrome. There is no effective drug therapy for this disease; therefore, lifestyle interventions remain as the first-line treatment. Nevertheless, the adherence rates to this type of treatment are very low, so great efforts are focused at finding novel therapeutic agents for the prevention of hepatic steatosis and its progression. This book presents a systematic and comprehensive revision about NAFLD, highlighting its epidemiological and molecular aspects, as well as its prevention and treatment. |
| format | Online |
| id | doab-20.500.12854ir-130297 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1302972024-03-31T22:44:25Z Non-Alcoholic Fatty Liver Disease Valenzuela, Rodrigo nafld, nonalcoholic steatohepatitis, nonalcoholic fatty liver disease, obesity, mitochondria, autophagy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology Nonalcoholic fatty liver disease (NAFLD) with a prevalence of 20-30% worldwide is characterized by the buildup of fat in the liver (liver steatosis) with no or little alcohol consumption. Its principal causes are modern diet and occidental lifestyle. It is characterized by metabolic disturbances such as insulin resistance, inflammation, and oxidative stress, considered as the hepatic manifestation of metabolic syndrome. There is no effective drug therapy for this disease; therefore, lifestyle interventions remain as the first-line treatment. Nevertheless, the adherence rates to this type of treatment are very low, so great efforts are focused at finding novel therapeutic agents for the prevention of hepatic steatosis and its progression. This book presents a systematic and comprehensive revision about NAFLD, highlighting its epidemiological and molecular aspects, as well as its prevention and treatment. 2023-12-01T17:16:54Z 2023-12-01T17:16:54Z 2018 book ONIX_20231201_9789535139249_1406 9789535139249 9789535139232 9789535140290 https://directory.doabooks.org/handle/20.500.12854/130297 eng image/jpeg n/a https://www.intechopen.com/books/6073 https://mts.intechopen.com/storage/books/6073/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/68045 10.5772/68045 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9789535139249 9789535139232 9789535140290 IntechOpen 190 open access |
| spellingShingle | nafld, nonalcoholic steatohepatitis, nonalcoholic fatty liver disease, obesity, mitochondria, autophagy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology Non-Alcoholic Fatty Liver Disease |
| title | Non-Alcoholic Fatty Liver Disease |
| title_full | Non-Alcoholic Fatty Liver Disease |
| title_fullStr | Non-Alcoholic Fatty Liver Disease |
| title_full_unstemmed | Non-Alcoholic Fatty Liver Disease |
| title_short | Non-Alcoholic Fatty Liver Disease |
| title_sort | non alcoholic fatty liver disease |
| topic | nafld, nonalcoholic steatohepatitis, nonalcoholic fatty liver disease, obesity, mitochondria, autophagy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology |
| topic_facet | nafld, nonalcoholic steatohepatitis, nonalcoholic fatty liver disease, obesity, mitochondria, autophagy thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology |
| url | ONIX_20231201_9789535139249_1406 |