Experimental Animal Models of Human Diseases

The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology....

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Argitaratua: IntechOpen 2023
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Sarrera elektronikoa:ONIX_20231201_9781789231656_1442
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collection Directory of Open Access Books
description The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.
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spelling doab-20.500.12854ir-1303332024-04-05T17:29:33Z Experimental Animal Models of Human Diseases Bartholomew, Ibeh obesity, inflammatory bowel disease, ulcerative colitis, blindness, animals, neovascularization thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models. 2023-12-01T17:20:17Z 2023-12-01T17:20:17Z 2018 book ONIX_20231201_9781789231656_1442 9781789231656 9781789231649 9781838812607 https://directory.doabooks.org/handle/20.500.12854/130333 eng image/jpeg n/a https://www.intechopen.com/books/5932 https://mts.intechopen.com/storage/books/5932/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/66030 10.5772/66030 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781789231656 9781789231649 9781838812607 IntechOpen 408 open access
spellingShingle obesity, inflammatory bowel disease, ulcerative colitis, blindness, animals, neovascularization
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences
Experimental Animal Models of Human Diseases
title Experimental Animal Models of Human Diseases
title_full Experimental Animal Models of Human Diseases
title_fullStr Experimental Animal Models of Human Diseases
title_full_unstemmed Experimental Animal Models of Human Diseases
title_short Experimental Animal Models of Human Diseases
title_sort experimental animal models of human diseases
topic obesity, inflammatory bowel disease, ulcerative colitis, blindness, animals, neovascularization
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences
topic_facet obesity, inflammatory bowel disease, ulcerative colitis, blindness, animals, neovascularization
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences
url ONIX_20231201_9781789231656_1442