Keratin
Keratin is the proteinaceous body covering layer produced by mammals, birds, fish, reptiles, and amphibians. Hair and wool, horns, claws, hooves, feathers, and scales are made of keratin. Keratin is insoluble in water and is resistant to proteolysis. Importantly, keratin is also the intracellular st...
Wedi'i Gadw mewn:
| Fformat: | Online |
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| Iaith: | Saesneg |
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IntechOpen
2023
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| Pynciau: | |
| Mynediad Ar-lein: | ONIX_20231201_9781789848052_1566 |
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Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
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| _version_ | 1869518720250937344 |
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| collection | Directory of Open Access Books |
| description | Keratin is the proteinaceous body covering layer produced by mammals, birds, fish, reptiles, and amphibians. Hair and wool, horns, claws, hooves, feathers, and scales are made of keratin. Keratin is insoluble in water and is resistant to proteolysis. Importantly, keratin is also the intracellular structural protein that protects living epithelial cells from mechanical damage or stress. The fundamental keratin functions are revealed in congenital human skin diseases caused by mutations in keratin genes, e.g., Epidermolysis bullosa simplex or Epidermolytic hyperkeratosis. Most keratin gene mutations have a dominant-negative effect disrupting the filamentous structure formation even from the natural allele, and leaving the cell with a deficient cytoskeleton. However, industrial scale meat production results in vast quantities of keratin byproduct. Processing this byproduct is, on the one hand a major challenge, and on the other hand, a potential for useful recycling and exploitation. |
| format | Online |
| id | doab-20.500.12854ir-130457 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1304572024-04-05T17:30:56Z Keratin Blumenberg, Miroslav skin barrier, keratins, keratinase, inflammation, bacteria, proteomics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) Keratin is the proteinaceous body covering layer produced by mammals, birds, fish, reptiles, and amphibians. Hair and wool, horns, claws, hooves, feathers, and scales are made of keratin. Keratin is insoluble in water and is resistant to proteolysis. Importantly, keratin is also the intracellular structural protein that protects living epithelial cells from mechanical damage or stress. The fundamental keratin functions are revealed in congenital human skin diseases caused by mutations in keratin genes, e.g., Epidermolysis bullosa simplex or Epidermolytic hyperkeratosis. Most keratin gene mutations have a dominant-negative effect disrupting the filamentous structure formation even from the natural allele, and leaving the cell with a deficient cytoskeleton. However, industrial scale meat production results in vast quantities of keratin byproduct. Processing this byproduct is, on the one hand a major challenge, and on the other hand, a potential for useful recycling and exploitation. 2023-12-01T17:37:35Z 2023-12-01T17:37:35Z 2018 book ONIX_20231201_9781789848052_1566 2632-0983 9781789848052 9781789848045 9781838817275 https://directory.doabooks.org/handle/20.500.12854/130457 eng Biochemistry image/jpeg n/a https://www.intechopen.com/books/6820 https://mts.intechopen.com/storage/books/6820/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.73230 10.5772/intechopen.73230 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781789848052 9781789848045 9781838817275 IntechOpen 2 180 open access |
| spellingShingle | skin barrier, keratins, keratinase, inflammation, bacteria, proteomics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) Keratin |
| title | Keratin |
| title_full | Keratin |
| title_fullStr | Keratin |
| title_full_unstemmed | Keratin |
| title_short | Keratin |
| title_sort | keratin |
| topic | skin barrier, keratins, keratinase, inflammation, bacteria, proteomics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) |
| topic_facet | skin barrier, keratins, keratinase, inflammation, bacteria, proteomics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) |
| url | ONIX_20231201_9781789848052_1566 |