Oncogenes and Carcinogenesis
Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viru...
Αποθηκεύτηκε σε:
| Μορφή: | Online |
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| Γλώσσα: | Αγγλικά |
| Έκδοση: |
IntechOpen
2023
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| Θέματα: | |
| Διαθέσιμο Online: | ONIX_20231201_9781789851724_1706 |
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| _version_ | 1869519157326774272 |
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| collection | Directory of Open Access Books |
| description | Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viruses. These carcinogens can induce specific genetic and epigenetic alterations in these tissues, leading to aberrant functioning of oncogenes and tumor suppressor genes. On the microRNAs (miRNAs) there are significant modifiers of both transcription and translation of oncogenes in carcinogenesis. In the last 50 years, several oncogenes and microRNAs related to these oncogenes have been identified in different types of human cancers. It is now clear that high expression of oncogenes, DNA damage response, and regulation of the cell cycle are related to the circadian clock. This book will mainly focus on the expressions of different oncogenes in breast, colon, and lung cancers. Moreover, readers will gain qualified scientific knowledge of the alterations in miRNAs in different types of cancers and the effects of the circadian clock on the expression of oncogenes in carcinogenesis. |
| format | Online |
| id | doab-20.500.12854ir-130597 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1305972024-03-31T22:45:53Z Oncogenes and Carcinogenesis Erkekoglu, Pinar breast cancer, colorectal cancer, lung cancer, mirna, dna repair, arsenic thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viruses. These carcinogens can induce specific genetic and epigenetic alterations in these tissues, leading to aberrant functioning of oncogenes and tumor suppressor genes. On the microRNAs (miRNAs) there are significant modifiers of both transcription and translation of oncogenes in carcinogenesis. In the last 50 years, several oncogenes and microRNAs related to these oncogenes have been identified in different types of human cancers. It is now clear that high expression of oncogenes, DNA damage response, and regulation of the cell cycle are related to the circadian clock. This book will mainly focus on the expressions of different oncogenes in breast, colon, and lung cancers. Moreover, readers will gain qualified scientific knowledge of the alterations in miRNAs in different types of cancers and the effects of the circadian clock on the expression of oncogenes in carcinogenesis. 2023-12-01T17:54:03Z 2023-12-01T17:54:03Z 2019 book ONIX_20231201_9781789851724_1706 9781789851724 9781789851717 9781839620621 https://directory.doabooks.org/handle/20.500.12854/130597 eng image/jpeg n/a https://www.intechopen.com/books/7281 https://mts.intechopen.com/storage/books/7281/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.74727 10.5772/intechopen.74727 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781789851724 9781789851717 9781839620621 IntechOpen 106 open access |
| spellingShingle | breast cancer, colorectal cancer, lung cancer, mirna, dna repair, arsenic thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Oncogenes and Carcinogenesis |
| title | Oncogenes and Carcinogenesis |
| title_full | Oncogenes and Carcinogenesis |
| title_fullStr | Oncogenes and Carcinogenesis |
| title_full_unstemmed | Oncogenes and Carcinogenesis |
| title_short | Oncogenes and Carcinogenesis |
| title_sort | oncogenes and carcinogenesis |
| topic | breast cancer, colorectal cancer, lung cancer, mirna, dna repair, arsenic thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | breast cancer, colorectal cancer, lung cancer, mirna, dna repair, arsenic thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20231201_9781789851724_1706 |