Ubiquitin Proteasome System
The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health...
I tiakina i:
| Hōputu: | Online |
|---|---|
| Reo: | Ingarihi |
| I whakaputaina: |
IntechOpen
2023
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| Ngā marau: | |
| Urunga tuihono: | ONIX_20231201_9781838804916_1717 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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| _version_ | 1869516314833321984 |
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| collection | Directory of Open Access Books |
| description | The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health and homeostasis. Numerous pathways within the UPS are implicated in disease, ranging from cancer to neurodegenerative diseases such as Parkinson's. The goal of this book is to deliver a collection of synopses of current areas of UPS research that highlights the importance of understanding the biology of the UPS to identify disease-relevant pathways, and the need to elucidate the molecular machinations within the UPS to develop methods for therapeutic modulation of these pathways. |
| format | Online |
| id | doab-20.500.12854ir-130608 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1306082024-04-05T17:30:52Z Ubiquitin Proteasome System Summers, Matthew cancer, ubiquitination, autophagy, immune system, dna damage, cell cycle thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health and homeostasis. Numerous pathways within the UPS are implicated in disease, ranging from cancer to neurodegenerative diseases such as Parkinson's. The goal of this book is to deliver a collection of synopses of current areas of UPS research that highlights the importance of understanding the biology of the UPS to identify disease-relevant pathways, and the need to elucidate the molecular machinations within the UPS to develop methods for therapeutic modulation of these pathways. 2023-12-01T17:56:45Z 2023-12-01T17:56:45Z 2019 book ONIX_20231201_9781838804916_1717 9781838804916 9781838804909 9781838807177 https://directory.doabooks.org/handle/20.500.12854/130608 eng image/jpeg n/a https://www.intechopen.com/books/8301 https://mts.intechopen.com/storage/books/8301/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.78430 10.5772/intechopen.78430 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781838804916 9781838804909 9781838807177 IntechOpen 226 open access |
| spellingShingle | cancer, ubiquitination, autophagy, immune system, dna damage, cell cycle thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Ubiquitin Proteasome System |
| title | Ubiquitin Proteasome System |
| title_full | Ubiquitin Proteasome System |
| title_fullStr | Ubiquitin Proteasome System |
| title_full_unstemmed | Ubiquitin Proteasome System |
| title_short | Ubiquitin Proteasome System |
| title_sort | ubiquitin proteasome system |
| topic | cancer, ubiquitination, autophagy, immune system, dna damage, cell cycle thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | cancer, ubiquitination, autophagy, immune system, dna damage, cell cycle thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20231201_9781838804916_1717 |