Hydrogels

Hydrogels, as three-dimensional polymer networks, are able to retain a large amount of water in their swollen state. The biomedical application of hydrogels was initially hampered by the toxicity of cross-linking agents and the limitations of hydrogel formation under physiological conditions. Howeve...

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Aineistotyyppi: Online
Kieli:englanti
Julkaistu: IntechOpen 2023
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Linkit:ONIX_20231201_9781789858761_1767
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collection Directory of Open Access Books
description Hydrogels, as three-dimensional polymer networks, are able to retain a large amount of water in their swollen state. The biomedical application of hydrogels was initially hampered by the toxicity of cross-linking agents and the limitations of hydrogel formation under physiological conditions. However, emerging knowledge in polymer chemistry and an increased understanding of biological processes have resulted in the design of versatile materials and minimally invasive therapies.The novel but challenging properties of hydrogels are attracting the attention of researchers in the biological, medical, and pharmaceutical fields. In the last few years, new methods have been developed for the preparation of hydrophilic polymers and hydrogels, which may be used in future biomedical and drug delivery applications. Such efforts include the synthesis of self-organized nanostructures based on triblock copolymers with applications in controlled drug delivery. These hydrogels could be used as carriers for drug delivery when combined with the techniques of drug imprinting and subsequent release. Engineered protein hydrogels have many potential advantages. They are excellent biomaterials and biodegradables. Furthermore, they could encapsulate drugs and be used in injectable forms to replace surgery, to repair damaged cartilage, in regenerative medicine, or in tissue engineering. Also, they have potential applications in gene therapy, although this field is relatively new.
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spelling doab-20.500.12854ir-1306582024-04-05T12:30:50Z Hydrogels Popa, Lăcrămioara Violeta Ghica, Mihaela Dinu-Pîrvu, Cristina-Elena drug delivery, chitosan, extracellular matrix, cellulose, textile, hyaluronic acid thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry Hydrogels, as three-dimensional polymer networks, are able to retain a large amount of water in their swollen state. The biomedical application of hydrogels was initially hampered by the toxicity of cross-linking agents and the limitations of hydrogel formation under physiological conditions. However, emerging knowledge in polymer chemistry and an increased understanding of biological processes have resulted in the design of versatile materials and minimally invasive therapies.The novel but challenging properties of hydrogels are attracting the attention of researchers in the biological, medical, and pharmaceutical fields. In the last few years, new methods have been developed for the preparation of hydrophilic polymers and hydrogels, which may be used in future biomedical and drug delivery applications. Such efforts include the synthesis of self-organized nanostructures based on triblock copolymers with applications in controlled drug delivery. These hydrogels could be used as carriers for drug delivery when combined with the techniques of drug imprinting and subsequent release. Engineered protein hydrogels have many potential advantages. They are excellent biomaterials and biodegradables. Furthermore, they could encapsulate drugs and be used in injectable forms to replace surgery, to repair damaged cartilage, in regenerative medicine, or in tissue engineering. Also, they have potential applications in gene therapy, although this field is relatively new. 2023-12-01T18:02:58Z 2023-12-01T18:02:58Z 2019 book ONIX_20231201_9781789858761_1767 9781789858761 9781789858754 9781839621215 https://directory.doabooks.org/handle/20.500.12854/130658 eng image/jpeg n/a https://www.intechopen.com/books/8353 https://mts.intechopen.com/storage/books/8353/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.78482 10.5772/intechopen.78482 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781789858761 9781789858754 9781839621215 IntechOpen 132 open access
spellingShingle drug delivery, chitosan, extracellular matrix, cellulose, textile, hyaluronic acid
thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
Hydrogels
title Hydrogels
title_full Hydrogels
title_fullStr Hydrogels
title_full_unstemmed Hydrogels
title_short Hydrogels
title_sort hydrogels
topic drug delivery, chitosan, extracellular matrix, cellulose, textile, hyaluronic acid
thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
topic_facet drug delivery, chitosan, extracellular matrix, cellulose, textile, hyaluronic acid
thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
url ONIX_20231201_9781789858761_1767