Modulating Gene Expression
RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the ot...
में बचाया:
| स्वरूप: | Online |
|---|---|
| भाषा: | अंग्रेज़ी |
| प्रकाशित: |
IntechOpen
2023
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| विषय: | |
| ऑनलाइन पहुंच: | ONIX_20231201_9781838806972_1860 |
| टैग: |
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
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| _version_ | 1869525907118489600 |
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| collection | Directory of Open Access Books |
| description | RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders. |
| format | Online |
| id | doab-20.500.12854ir-130751 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1307512024-03-31T22:45:28Z Modulating Gene Expression Singh, Aditi Khan, Mohammad W. machine learning, breast cancer, gene therapy, clinical trials, nanoparticle, crispr/cas9 thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders. 2023-12-01T18:12:21Z 2023-12-01T18:12:21Z 2019 book ONIX_20231201_9781838806972_1860 9781838806972 9781838806965 9781838806989 https://directory.doabooks.org/handle/20.500.12854/130751 eng image/jpeg n/a https://www.intechopen.com/books/7331 https://mts.intechopen.com/storage/books/7331/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.75144 10.5772/intechopen.75144 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781838806972 9781838806965 9781838806989 IntechOpen 134 open access |
| spellingShingle | machine learning, breast cancer, gene therapy, clinical trials, nanoparticle, crispr/cas9 thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics Modulating Gene Expression |
| title | Modulating Gene Expression |
| title_full | Modulating Gene Expression |
| title_fullStr | Modulating Gene Expression |
| title_full_unstemmed | Modulating Gene Expression |
| title_short | Modulating Gene Expression |
| title_sort | modulating gene expression |
| topic | machine learning, breast cancer, gene therapy, clinical trials, nanoparticle, crispr/cas9 thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics |
| topic_facet | machine learning, breast cancer, gene therapy, clinical trials, nanoparticle, crispr/cas9 thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics |
| url | ONIX_20231201_9781838806972_1860 |