Selected Topics in Myasthenia Gravis
Myasthenia gravis is a rare potentially fatal chronic autoimmune disorder. Circulating autoantibodies directed against components of the neuromuscular junction of skeletal muscles, most commonly nicotinic acetylcholine receptor and associated protein in the postsynaptic membrane, block neuromuscular...
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| Format: | Online |
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| Sprog: | engelsk |
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IntechOpen
2023
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| Online adgang: | ONIX_20231201_9781838808303_1931 |
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| _version_ | 1869528984378671104 |
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| collection | Directory of Open Access Books |
| description | Myasthenia gravis is a rare potentially fatal chronic autoimmune disorder. Circulating autoantibodies directed against components of the neuromuscular junction of skeletal muscles, most commonly nicotinic acetylcholine receptor and associated protein in the postsynaptic membrane, block neuromuscular transmission resulting in muscle weakness. This muscle weakness typically worsens with continued activity, improves on rest, and is of variable severity ranging from mild ocular muscle weakness to severe generalized muscle weakness, involving the respiratory muscle with impending respiratory failure. The worldwide prevalence of myasthenia gravis is 100-200 per million population, affecting more than 700,000 people all over the world. The prevalence rate has increased since the 1950s due to improved diagnostic precision and decreased mortality rate. |
| format | Online |
| id | doab-20.500.12854ir-130822 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1308222024-04-01T14:15:21Z Selected Topics in Myasthenia Gravis Jaber Al-Zwaini, Isam AL-Mayahi, Ali pregnancy, autoimmunity, autoantibodies, crystal structure, drug therapy, neonates thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology Myasthenia gravis is a rare potentially fatal chronic autoimmune disorder. Circulating autoantibodies directed against components of the neuromuscular junction of skeletal muscles, most commonly nicotinic acetylcholine receptor and associated protein in the postsynaptic membrane, block neuromuscular transmission resulting in muscle weakness. This muscle weakness typically worsens with continued activity, improves on rest, and is of variable severity ranging from mild ocular muscle weakness to severe generalized muscle weakness, involving the respiratory muscle with impending respiratory failure. The worldwide prevalence of myasthenia gravis is 100-200 per million population, affecting more than 700,000 people all over the world. The prevalence rate has increased since the 1950s due to improved diagnostic precision and decreased mortality rate. 2023-12-01T18:19:33Z 2023-12-01T18:19:33Z 2019 book ONIX_20231201_9781838808303_1931 9781838808303 9781838808297 9781838808310 https://directory.doabooks.org/handle/20.500.12854/130822 eng image/jpeg n/a https://www.intechopen.com/books/7160 https://mts.intechopen.com/storage/books/7160/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.73959 10.5772/intechopen.73959 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781838808303 9781838808297 9781838808310 IntechOpen 94 open access |
| spellingShingle | pregnancy, autoimmunity, autoantibodies, crystal structure, drug therapy, neonates thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology Selected Topics in Myasthenia Gravis |
| title | Selected Topics in Myasthenia Gravis |
| title_full | Selected Topics in Myasthenia Gravis |
| title_fullStr | Selected Topics in Myasthenia Gravis |
| title_full_unstemmed | Selected Topics in Myasthenia Gravis |
| title_short | Selected Topics in Myasthenia Gravis |
| title_sort | selected topics in myasthenia gravis |
| topic | pregnancy, autoimmunity, autoantibodies, crystal structure, drug therapy, neonates thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology |
| topic_facet | pregnancy, autoimmunity, autoantibodies, crystal structure, drug therapy, neonates thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology |
| url | ONIX_20231201_9781838808303_1931 |