Advances in Hepatology

This book discusses clinical advances in hepatology, with a focus on metabolic diseases and chronic hepatitis C. The development of direct-acting antiviral (DAA) agents for the treatment of hepatitis C virus (HCV) infection in 2010 has completely transformed the management of this disease. This tran...

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Argitaratua: IntechOpen 2023
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collection Directory of Open Access Books
description This book discusses clinical advances in hepatology, with a focus on metabolic diseases and chronic hepatitis C. The development of direct-acting antiviral (DAA) agents for the treatment of hepatitis C virus (HCV) infection in 2010 has completely transformed the management of this disease. This transformative nature of DAA therapy underpins the goal of the World Health Organization (WHO) to eliminate HCV infection as a public health threat by 2030. The advantages of using these therapies include high efficacy (sustained virological response rate >95%) with minimal side effects, good tolerability, easy drug administration (once-daily oral dosing) and short duration of treatment (8-12 weeks). The commercialization of second-generation DAA agents due to their high effectiveness, few side-effects and pangenotypic action. This transformative nature of DAA therapy underpins the goal of the WHO to eliminate HCV infection as a public health threat by 2030.
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institution Directory of Open Access Books
language eng
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publishDateRange 2023
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publisher IntechOpen
publisherStr IntechOpen
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spelling doab-20.500.12854ir-1309622024-03-31T22:44:25Z Advances in Hepatology Rodrigo, Luis Martins, Ian Guo, Xiaozhong Qi, Xingshun cirrhosis, hepatitis c, chronic hepatitis c, bacteria, hepatocellular carcinoma, gene expression thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology This book discusses clinical advances in hepatology, with a focus on metabolic diseases and chronic hepatitis C. The development of direct-acting antiviral (DAA) agents for the treatment of hepatitis C virus (HCV) infection in 2010 has completely transformed the management of this disease. This transformative nature of DAA therapy underpins the goal of the World Health Organization (WHO) to eliminate HCV infection as a public health threat by 2030. The advantages of using these therapies include high efficacy (sustained virological response rate >95%) with minimal side effects, good tolerability, easy drug administration (once-daily oral dosing) and short duration of treatment (8-12 weeks). The commercialization of second-generation DAA agents due to their high effectiveness, few side-effects and pangenotypic action. This transformative nature of DAA therapy underpins the goal of the WHO to eliminate HCV infection as a public health threat by 2030. 2023-12-01T18:35:01Z 2023-12-01T18:35:01Z 2021 book ONIX_20231201_9781839686245_2072 9781839686245 9781839686238 9781839686252 https://directory.doabooks.org/handle/20.500.12854/130962 eng image/jpeg n/a https://www.intechopen.com/books/10326 https://mts.intechopen.com/storage/books/10326/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.91512 10.5772/intechopen.91512 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781839686245 9781839686238 9781839686252 IntechOpen 258 open access
spellingShingle cirrhosis, hepatitis c, chronic hepatitis c, bacteria, hepatocellular carcinoma, gene expression
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology
Advances in Hepatology
title Advances in Hepatology
title_full Advances in Hepatology
title_fullStr Advances in Hepatology
title_full_unstemmed Advances in Hepatology
title_short Advances in Hepatology
title_sort advances in hepatology
topic cirrhosis, hepatitis c, chronic hepatitis c, bacteria, hepatocellular carcinoma, gene expression
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology
topic_facet cirrhosis, hepatitis c, chronic hepatitis c, bacteria, hepatocellular carcinoma, gene expression
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJJ Hepatology
url ONIX_20231201_9781839686245_2072