Applications of RNA-Seq in Biology and Medicine
This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of di...
Tallennettuna:
| Aineistotyyppi: | Online |
|---|---|
| Kieli: | englanti |
| Julkaistu: |
IntechOpen
2023
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| Aiheet: | |
| Linkit: | ONIX_20231201_9781839628153_2368 |
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| _version_ | 1869521908804878336 |
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| collection | Directory of Open Access Books |
| description | This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of differentially spliced RNA isoforms. Assessment of gene expression by RNA-Seq provides new insight into host response to pathogens, drugs, allergens, and other environmental triggers. RNA-Seq allows us to accurately capture all subtypes of RNA molecules, in any sequenced organism or single-cell type, under different experimental conditions. Merging genomics and transcriptomic profiling provides novel information underlying causative DNA mutations. Combining RNA-Seq with immunoprecipitation and cross-linking techniques is a clever multi-omics strategy assessing transcriptional, post-transcriptional and post-translational levels of gene expression regulation. |
| format | Online |
| id | doab-20.500.12854ir-131257 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | IntechOpen |
| publisherStr | IntechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1312572024-04-05T17:30:55Z Applications of RNA-Seq in Biology and Medicine Louis, Irina Vlasova-St. transcriptome, gene expression, genes, dysbiosis, biofilms, metagenomics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology This book evaluates and comprehensively summarizes the scientific findings that have been achieved through RNA-sequencing (RNA-Seq) technology. RNA-Seq transcriptome profiling of healthy and diseased tissues allows FOR understanding the alterations in cellular phenotypes through the expression of differentially spliced RNA isoforms. Assessment of gene expression by RNA-Seq provides new insight into host response to pathogens, drugs, allergens, and other environmental triggers. RNA-Seq allows us to accurately capture all subtypes of RNA molecules, in any sequenced organism or single-cell type, under different experimental conditions. Merging genomics and transcriptomic profiling provides novel information underlying causative DNA mutations. Combining RNA-Seq with immunoprecipitation and cross-linking techniques is a clever multi-omics strategy assessing transcriptional, post-transcriptional and post-translational levels of gene expression regulation. 2023-12-01T19:06:32Z 2023-12-01T19:06:32Z 2021 book ONIX_20231201_9781839628153_2368 9781839628153 9781839626869 9781839628160 https://directory.doabooks.org/handle/20.500.12854/131257 eng image/jpeg n/a https://www.intechopen.com/books/10369 https://mts.intechopen.com/storage/books/10369/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.91555 10.5772/intechopen.91555 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781839628153 9781839626869 9781839628160 IntechOpen 142 open access |
| spellingShingle | transcriptome, gene expression, genes, dysbiosis, biofilms, metagenomics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology Applications of RNA-Seq in Biology and Medicine |
| title | Applications of RNA-Seq in Biology and Medicine |
| title_full | Applications of RNA-Seq in Biology and Medicine |
| title_fullStr | Applications of RNA-Seq in Biology and Medicine |
| title_full_unstemmed | Applications of RNA-Seq in Biology and Medicine |
| title_short | Applications of RNA-Seq in Biology and Medicine |
| title_sort | applications of rna seq in biology and medicine |
| topic | transcriptome, gene expression, genes, dysbiosis, biofilms, metagenomics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology |
| topic_facet | transcriptome, gene expression, genes, dysbiosis, biofilms, metagenomics thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology |
| url | ONIX_20231201_9781839628153_2368 |