Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models
Translational research is required to uncover the underlying pathomechanisms of neurological and psychiatric disorders, search for new biomarkers, and develop novel therapeutics. Complex polygenic, multifactorial, and heterogeneous mechanisms have been elucidated using in vivo and in vitro models. A...
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| Materialtyp: | Online |
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| Språk: | engelska |
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MDPI - Multidisciplinary Digital Publishing Institute
2024
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| Länkar: | ONIX_20240108_9783036596563_9 |
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| _version_ | 1869529784032165888 |
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| collection | Directory of Open Access Books |
| description | Translational research is required to uncover the underlying pathomechanisms of neurological and psychiatric disorders, search for new biomarkers, and develop novel therapeutics. Complex polygenic, multifactorial, and heterogeneous mechanisms have been elucidated using in vivo and in vitro models. Advanced preclinical models have recently revealed an intriguing interaction between sex/gender and aging in the pathogenesis and clinical manifestations of neuropsychiatric disorders. Despite these advances, much work remains to be carried out to fully understand the underlying pathology of these conditions and to develop treatments that can significantly improve the lives of those who suffer from them. The current challenge in the field of neurological and psychiatric disorders is the development of disease-modifying, effective treatments for these complex and long-term debilitating conditions with a high malady burden. The first edition of this research topic, entitled 'Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models,' emphasizes the importance of translational research in bridging the gap between basic research and clinical applications. Furthermore, it provided a venue for researchers to share their findings and progress in translational research in this field. |
| format | Online |
| id | doab-20.500.12854ir-132350 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1323502024-03-31T13:08:33Z Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models Tanaka, Masaru Giménez-Llort, Lydia Alzheimer&rsquo s disease Parkinson&rsquo multiple sclerosis stroke migraine pain depressive disorder anxiety disorder autism spectrum disorder sleep wake disorders thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Translational research is required to uncover the underlying pathomechanisms of neurological and psychiatric disorders, search for new biomarkers, and develop novel therapeutics. Complex polygenic, multifactorial, and heterogeneous mechanisms have been elucidated using in vivo and in vitro models. Advanced preclinical models have recently revealed an intriguing interaction between sex/gender and aging in the pathogenesis and clinical manifestations of neuropsychiatric disorders. Despite these advances, much work remains to be carried out to fully understand the underlying pathology of these conditions and to develop treatments that can significantly improve the lives of those who suffer from them. The current challenge in the field of neurological and psychiatric disorders is the development of disease-modifying, effective treatments for these complex and long-term debilitating conditions with a high malady burden. The first edition of this research topic, entitled 'Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models,' emphasizes the importance of translational research in bridging the gap between basic research and clinical applications. Furthermore, it provided a venue for researchers to share their findings and progress in translational research in this field. 2024-01-08T14:37:41Z 2024-01-08T14:37:41Z 2023 book ONIX_20240108_9783036596563_9 9783036596563 9783036596570 https://directory.doabooks.org/handle/20.500.12854/132350 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/topic/8354 https://mdpi.com/books/pdfview/topic/8354 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9657-0 10.3390/books978-3-0365-9657-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036596563 9783036596570 522 Basel open access |
| spellingShingle | Alzheimer&rsquo s disease Parkinson&rsquo multiple sclerosis stroke migraine pain depressive disorder anxiety disorder autism spectrum disorder sleep wake disorders thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models |
| title | Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models |
| title_full | Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models |
| title_fullStr | Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models |
| title_full_unstemmed | Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models |
| title_short | Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models |
| title_sort | emerging translational research in neurological and psychiatric diseases from in vitro to in vivo models |
| topic | Alzheimer&rsquo s disease Parkinson&rsquo multiple sclerosis stroke migraine pain depressive disorder anxiety disorder autism spectrum disorder sleep wake disorders thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | Alzheimer&rsquo s disease Parkinson&rsquo multiple sclerosis stroke migraine pain depressive disorder anxiety disorder autism spectrum disorder sleep wake disorders thema EDItEUR::M Medicine and Nursing thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | ONIX_20240108_9783036596563_9 |