Novel Approaches for Targeting Metalloproteinases
This Special Issue is a collection of eleven articles (five reviews and six studies) that describe a wide range of approaches to modulating metalloproteinase activity in disease. The techniques described are in vitro, in vivo, and ex vivo.
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| Formaat: | Online |
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| Taal: | Engels |
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MDPI - Multidisciplinary Digital Publishing Institute
2024
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| Online toegang: | ONIX_20240108_9783036597096_113 |
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| _version_ | 1869519506838126592 |
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| collection | Directory of Open Access Books |
| description | This Special Issue is a collection of eleven articles (five reviews and six studies) that describe a wide range of approaches to modulating metalloproteinase activity in disease. The techniques described are in vitro, in vivo, and ex vivo. |
| format | Online |
| id | doab-20.500.12854ir-132454 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1324542024-03-28T03:31:11Z Novel Approaches for Targeting Metalloproteinases Santamaria, Salvatore carbohydrates glycoconjugates MMPs ADAMs iminosugars metzincin inhibitors matrix metalloproteinases (MMPs), protease tissue inhibitors of metalloproteinases (TIMPs), exosite small molecule inhibitors monoclonal antibodies proteomics N-terminomics terminal amine isotopic labeling of substrates (TAILS) MMP-2 MMP-9 Alzheimer’s disease AD neurodegeneration neuroinflammation natural compounds marine compounds terrestrial compounds nutraceuticals Matrix Metalloproteinase inhibitors bone targeting bisphosphonates antitumor agents skeletal malignancies osteoarthritis cartilage metalloproteinase targeting meprin α meprin β zinc metalloproteinase medicinal chemistry probe development uHTS dipeptidyl peptidase III coumarin derivatives inhibitor molecular modeling β-blockers carvedilol matrix metalloproteinase-2 ischemia-reperfusion injury isolated heart perfusion kidney obeticholic acid ischemia/reperfusion liver metalloproteinases MMP-2 inhibitor cardiac dysfunction ischemia n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry This Special Issue is a collection of eleven articles (five reviews and six studies) that describe a wide range of approaches to modulating metalloproteinase activity in disease. The techniques described are in vitro, in vivo, and ex vivo. 2024-01-08T14:54:34Z 2024-01-08T14:54:34Z 2023 book ONIX_20240108_9783036597096_113 9783036597096 9783036597089 https://directory.doabooks.org/handle/20.500.12854/132454 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/8494 https://mdpi.com/books/pdfview/book/8494 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9708-9 10.3390/books978-3-0365-9708-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036597096 9783036597089 214 Basel open access |
| spellingShingle | carbohydrates glycoconjugates MMPs ADAMs iminosugars metzincin inhibitors matrix metalloproteinases (MMPs), protease tissue inhibitors of metalloproteinases (TIMPs), exosite small molecule inhibitors monoclonal antibodies proteomics N-terminomics terminal amine isotopic labeling of substrates (TAILS) MMP-2 MMP-9 Alzheimer’s disease AD neurodegeneration neuroinflammation natural compounds marine compounds terrestrial compounds nutraceuticals Matrix Metalloproteinase inhibitors bone targeting bisphosphonates antitumor agents skeletal malignancies osteoarthritis cartilage metalloproteinase targeting meprin α meprin β zinc metalloproteinase medicinal chemistry probe development uHTS dipeptidyl peptidase III coumarin derivatives inhibitor molecular modeling β-blockers carvedilol matrix metalloproteinase-2 ischemia-reperfusion injury isolated heart perfusion kidney obeticholic acid ischemia/reperfusion liver metalloproteinases MMP-2 inhibitor cardiac dysfunction ischemia n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry Novel Approaches for Targeting Metalloproteinases |
| title | Novel Approaches for Targeting Metalloproteinases |
| title_full | Novel Approaches for Targeting Metalloproteinases |
| title_fullStr | Novel Approaches for Targeting Metalloproteinases |
| title_full_unstemmed | Novel Approaches for Targeting Metalloproteinases |
| title_short | Novel Approaches for Targeting Metalloproteinases |
| title_sort | novel approaches for targeting metalloproteinases |
| topic | carbohydrates glycoconjugates MMPs ADAMs iminosugars metzincin inhibitors matrix metalloproteinases (MMPs), protease tissue inhibitors of metalloproteinases (TIMPs), exosite small molecule inhibitors monoclonal antibodies proteomics N-terminomics terminal amine isotopic labeling of substrates (TAILS) MMP-2 MMP-9 Alzheimer’s disease AD neurodegeneration neuroinflammation natural compounds marine compounds terrestrial compounds nutraceuticals Matrix Metalloproteinase inhibitors bone targeting bisphosphonates antitumor agents skeletal malignancies osteoarthritis cartilage metalloproteinase targeting meprin α meprin β zinc metalloproteinase medicinal chemistry probe development uHTS dipeptidyl peptidase III coumarin derivatives inhibitor molecular modeling β-blockers carvedilol matrix metalloproteinase-2 ischemia-reperfusion injury isolated heart perfusion kidney obeticholic acid ischemia/reperfusion liver metalloproteinases MMP-2 inhibitor cardiac dysfunction ischemia n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| topic_facet | carbohydrates glycoconjugates MMPs ADAMs iminosugars metzincin inhibitors matrix metalloproteinases (MMPs), protease tissue inhibitors of metalloproteinases (TIMPs), exosite small molecule inhibitors monoclonal antibodies proteomics N-terminomics terminal amine isotopic labeling of substrates (TAILS) MMP-2 MMP-9 Alzheimer’s disease AD neurodegeneration neuroinflammation natural compounds marine compounds terrestrial compounds nutraceuticals Matrix Metalloproteinase inhibitors bone targeting bisphosphonates antitumor agents skeletal malignancies osteoarthritis cartilage metalloproteinase targeting meprin α meprin β zinc metalloproteinase medicinal chemistry probe development uHTS dipeptidyl peptidase III coumarin derivatives inhibitor molecular modeling β-blockers carvedilol matrix metalloproteinase-2 ischemia-reperfusion injury isolated heart perfusion kidney obeticholic acid ischemia/reperfusion liver metalloproteinases MMP-2 inhibitor cardiac dysfunction ischemia n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry |
| url | ONIX_20240108_9783036597096_113 |