Antitumor Activity of Natural Products and Related Compounds
Cancer is one of the leading causes of morbidity and mortality in humans today, and the number of people affected by cancer is growing. As a result, the search for new antitumor agents that may be more effective and secure than existing treatments is an ongoing effort. Nature provides a wide range o...
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| Формат: | Online |
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| Язык: | английский |
| Опубликовано: |
MDPI - Multidisciplinary Digital Publishing Institute
2024
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| Предметы: | |
| Online-ссылка: | ONIX_20240108_9783036597461_117 |
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Нет меток, Требуется 1-ая метка записи!
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| _version_ | 1869519561656631296 |
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| collection | Directory of Open Access Books |
| description | Cancer is one of the leading causes of morbidity and mortality in humans today, and the number of people affected by cancer is growing. As a result, the search for new antitumor agents that may be more effective and secure than existing treatments is an ongoing effort. Nature provides a wide range of compounds with a great variety of chemical scaffolds and distinct bioactivity profiles. Indeed, natural products are a rich source of bioactive molecules that, over the years, have found application in the treatment of many diseases, including cancer. Natural products have played an important role in chemotherapy and chemoprevention by providing antitumor drugs such as camptothecin, doxorubicin, paclitaxel, vinblastine, and vincristine, as well as understanding the cellular and molecular mechanisms underlying antitumor activity. Significant advances in natural source isolation and extraction techniques have enabled the identification of novel lead compounds as useful starting points for the generation of optimized molecules with enhanced therapeutic potential via semi-synthetic or synthetic processes. The focus of this Topic is on natural substances derived from plants or animals, as well as their synthetic derivatives, which have been investigated for their ability to counteract cancer progression. |
| format | Online |
| id | doab-20.500.12854ir-132458 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-1324582024-03-28T03:32:51Z Antitumor Activity of Natural Products and Related Compounds De Filippis, Barbara Ammazzalorso, Alessandra Fantacuzzi, Marialuigia natural compounds natural derivatives anticancer drug discovery antiproliferation thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry Cancer is one of the leading causes of morbidity and mortality in humans today, and the number of people affected by cancer is growing. As a result, the search for new antitumor agents that may be more effective and secure than existing treatments is an ongoing effort. Nature provides a wide range of compounds with a great variety of chemical scaffolds and distinct bioactivity profiles. Indeed, natural products are a rich source of bioactive molecules that, over the years, have found application in the treatment of many diseases, including cancer. Natural products have played an important role in chemotherapy and chemoprevention by providing antitumor drugs such as camptothecin, doxorubicin, paclitaxel, vinblastine, and vincristine, as well as understanding the cellular and molecular mechanisms underlying antitumor activity. Significant advances in natural source isolation and extraction techniques have enabled the identification of novel lead compounds as useful starting points for the generation of optimized molecules with enhanced therapeutic potential via semi-synthetic or synthetic processes. The focus of this Topic is on natural substances derived from plants or animals, as well as their synthetic derivatives, which have been investigated for their ability to counteract cancer progression. 2024-01-08T14:55:13Z 2024-01-08T14:55:13Z 2023 book ONIX_20240108_9783036597461_117 9783036597461 9783036597478 https://directory.doabooks.org/handle/20.500.12854/132458 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/topic/8498 https://mdpi.com/books/pdfview/topic/8498 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-9747-8 10.3390/books978-3-0365-9747-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036597461 9783036597478 616 Basel open access |
| spellingShingle | natural compounds natural derivatives anticancer drug discovery antiproliferation thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry Antitumor Activity of Natural Products and Related Compounds |
| title | Antitumor Activity of Natural Products and Related Compounds |
| title_full | Antitumor Activity of Natural Products and Related Compounds |
| title_fullStr | Antitumor Activity of Natural Products and Related Compounds |
| title_full_unstemmed | Antitumor Activity of Natural Products and Related Compounds |
| title_short | Antitumor Activity of Natural Products and Related Compounds |
| title_sort | antitumor activity of natural products and related compounds |
| topic | natural compounds natural derivatives anticancer drug discovery antiproliferation thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry |
| topic_facet | natural compounds natural derivatives anticancer drug discovery antiproliferation thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PN Chemistry |
| url | ONIX_20240108_9783036597461_117 |