Crohn’s Disease

Crohn’s disease (CD) is a subtype of inflammatory bowel disease (IBD) that can affect any part of the intestine and can lead to stricture, fistula, and abscess if left untreated. This book highlights the key aspects of the current state of the art of pathogenesis, diagnosis, and therapy for CD and i...

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Baskı/Yayın Bilgisi: IntechOpen 2024
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Online Erişim:ONIX_20240307_9781837680481_227
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description Crohn’s disease (CD) is a subtype of inflammatory bowel disease (IBD) that can affect any part of the intestine and can lead to stricture, fistula, and abscess if left untreated. This book highlights the key aspects of the current state of the art of pathogenesis, diagnosis, and therapy for CD and its unique complications. CD has evolved from clinical observations to a network of advanced therapies and quality of care. Among the pathogenetic factors, a significant proportion of the latest research is focused on the gut microbiome, as rapidly changing environmental factors exert their effects primarily by altering the microbiome. This book highlights the enigmatic crosstalk between the gut microbiome and CD. Going further, CD is a great mimicker that is important to differentiate from other diseases, especially intestinal tuberculosis, which is still a significant problem in tuberculosis-endemic countries. This book addresses this issue as well. Among the diagnostic modalities, capsule endoscopy is a non-invasive, radiation-free, and accurate modality for pan-enteric evaluation. The book examines the role of capsule endoscopy in suspected and established CD, including its pros and cons in these scenarios. It also highlights technical advancements in the field. Among the complications of CD, the most dreaded is fistula. Apart from traditional medical and surgical therapies, interventional inflammatory bowel disease (IIBD) therapies like endoscopic fistulotomy and abscess drainage can decrease surgical morbidity and improve patient outcomes. The book reviews the current role and details of such therapies. Overall, this book provides insights into current advances in CD pathogenesis, diagnosis, and management.
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spelling doab-20.500.12854ir-1353192024-03-31T22:44:23Z Crohn’s Disease Pal, Partha inflammatory bowel disease microbiome dysbiosis behçet’s disease tuberculosis autoimmune diseases thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJH Gastroenterology Crohn’s disease (CD) is a subtype of inflammatory bowel disease (IBD) that can affect any part of the intestine and can lead to stricture, fistula, and abscess if left untreated. This book highlights the key aspects of the current state of the art of pathogenesis, diagnosis, and therapy for CD and its unique complications. CD has evolved from clinical observations to a network of advanced therapies and quality of care. Among the pathogenetic factors, a significant proportion of the latest research is focused on the gut microbiome, as rapidly changing environmental factors exert their effects primarily by altering the microbiome. This book highlights the enigmatic crosstalk between the gut microbiome and CD. Going further, CD is a great mimicker that is important to differentiate from other diseases, especially intestinal tuberculosis, which is still a significant problem in tuberculosis-endemic countries. This book addresses this issue as well. Among the diagnostic modalities, capsule endoscopy is a non-invasive, radiation-free, and accurate modality for pan-enteric evaluation. The book examines the role of capsule endoscopy in suspected and established CD, including its pros and cons in these scenarios. It also highlights technical advancements in the field. Among the complications of CD, the most dreaded is fistula. Apart from traditional medical and surgical therapies, interventional inflammatory bowel disease (IIBD) therapies like endoscopic fistulotomy and abscess drainage can decrease surgical morbidity and improve patient outcomes. The book reviews the current role and details of such therapies. Overall, this book provides insights into current advances in CD pathogenesis, diagnosis, and management. 2024-03-07T17:08:50Z 2024-03-07T17:08:50Z 2023 book ONIX_20240307_9781837680481_227 9781837680481 9781837680474 9781837680498 https://directory.doabooks.org/handle/20.500.12854/135319 eng image/jpeg n/a https://www.intechopen.com/books/12185 https://mts.intechopen.com/storage/books/12185/authors_book/authors_book.pdf IntechOpen IntechOpen 10.5772/intechopen.104329 10.5772/intechopen.104329 78a36484-2c0c-47cb-ad67-2b9f5cd4a8f6 9781837680481 9781837680474 9781837680498 IntechOpen 112 open access
spellingShingle inflammatory bowel disease
microbiome
dysbiosis
behçet’s disease
tuberculosis
autoimmune diseases
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJH Gastroenterology
Crohn’s Disease
title Crohn’s Disease
title_full Crohn’s Disease
title_fullStr Crohn’s Disease
title_full_unstemmed Crohn’s Disease
title_short Crohn’s Disease
title_sort crohn s disease
topic inflammatory bowel disease
microbiome
dysbiosis
behçet’s disease
tuberculosis
autoimmune diseases
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJH Gastroenterology
topic_facet inflammatory bowel disease
microbiome
dysbiosis
behçet’s disease
tuberculosis
autoimmune diseases
thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJH Gastroenterology
url ONIX_20240307_9781837680481_227